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Protective effect of remote ischemic per-conditioning in the Protective effect of remote ischemic per-conditioning in the Protective effect of remote ischemic per-conditioning in the Protective effect of remote ischemic per-conditioning in the Protective effect of remote ischemic per-conditioning in the ischemia and reperfusion-induce renal injury in rats ischemia and reperfusion-induce renal injury in rats ischemia and reperfusion-induce renal injury in rats ischemia and reperfusion-induce renal injury in rats ischemia and reperfusion-induce renal injury in rats Efeito protetor do per-condicionamento isquêmico remoto nas lesões da Efeito protetor do per-condicionamento isquêmico remoto nas lesões da Efeito protetor do per-condicionamento isquêmico remoto nas lesões da Efeito protetor do per-condicionamento isquêmico remoto nas lesões da Efeito protetor do per-condicionamento isquêmico remoto nas lesões da síndrome de isquemia e reperfusão renal em ratos síndrome de isquemia e reperfusão renal em ratos síndrome de isquemia e reperfusão renal em ratos síndrome de isquemia e reperfusão renal em ratos síndrome de isquemia e reperfusão renal em ratos Fifteen rats (Rattus norvegicus) were randomized into three groups (n = 5): Group Normality (GN), ControlIschemia and Reperfusion (GIR) and Group remote ischemic per-conditioning (GPER). With the exception of the GN group, all others underwent renal ischemia for 30 minutes. In group GPER we performed the ischemic remote per-conditioning, consisting of three cycles of ischemia and reperfusion applied every five minutes during the ischemic period, to the left hindlimb of the rats by means of a tourniquet. To quantify the lesions we measured serum levels of creatinine and urea, as well as analyzed renal histopathology. Results Results ResultsResults Results: The GPER group presented with better levels of urea (83.74 ± 14.58%) and creatinine (0.72 ± 26.14%) when compared to GIR group, approaching the GN group. Histopathologically, the lower levels of medullary congestion and hydropic degeneration were found in group GPER. Conclusion Conclusion Conclusion Conclusion Conclusion: The remote ischemic per-conditioning had a significant protective effect on renal ischemia and reperfusion.

Objective: To evaluate the influence of the understanding of brain death in relation to organ donation in patients from the Marco School Health Center, which is linked to the Universidade do Estado do Pará.Methods: A total of 136 patients were interviewed based on a research protocol. The interview results were subsequently analyzed with regard to the understanding of brain death and organ donation in addition to the collection of sociodemographic data.Results: The majority of patients were female and were in favor of organ donation, with a mean age of 39 years being observed. Only 19.9% of the patients understood the meaning of brain death, and 85.3% believed that physicians may be mistaken in confirming the status of brain death of a patient, while 18.4% trusted the diagnosis of brain death. A statistically significant (p < 0.01) correlation was observed between the degree of confidence in the diagnosis of brain death and the person's agreement to donate his/her organs after death.Conclusion: The majority of the population under study did not understand the meaning of brain death and had a low degree of confidence in the diagnosis of brain death. This lack of understanding and confidence negatively influences the desire to donate organs.

The impact factor is a determinant factor on the ethics included in the instructions to authors of articles in scientific journals, showing that higher-quality journals seek better-designed articles that are conscientious at the beginning of the research.

Gonçalves Gonçalves Gonçalves Gonçalves GonçalvesEffects of splenic allograft in lipid profile of non-splenectomized rats: the immune and metabolic role of the "double spleen"Original Article Original Article Original Article Original Article Original Article Effects of splenic allograft in lipid profile of non-splenectomized Effects of splenic allograft in lipid profile of non-splenectomized Effects of splenic allograft in lipid profile of non-splenectomized Effects of splenic allograft in lipid profile of non-splenectomized Effects of splenic allograft in lipid profile of non-splenectomized rats: the immune and metabolic role of the "double spleen" rats: the immune and metabolic role of the "double spleen" rats: the immune and metabolic role of the "double spleen" rats: the immune and metabolic role of the "double spleen" rats: the immune and metabolic role of the "double spleen"Efeitos do aloenxerto esplênico no lipidograma de ratos não esplenectomizados: Efeitos do aloenxerto esplênico no lipidograma de ratos não esplenectomizados: Efeitos do aloenxerto esplênico no lipidograma de ratos não esplenectomizados: Efeitos do aloenxerto esplênico no lipidograma de ratos não esplenectomizados: Efeitos do aloenxerto esplênico no lipidograma de ratos não esplenectomizados: papel imunológico e metabólico do "baço duplo" papel imunológico e metabólico do "baço duplo" papel imunológico e metabólico do "baço duplo" papel imunológico e metabólico do "baço duplo" papel imunológico e metabólico do "baço duplo" (1), total splenectomy group (2), splenectomy and implantation of allograft group (3) and double spleen group (4). Each group was subdivided into two subgroups: A and B, based on the death of the animals after 30 or 120 days of monitoring. The procedures in groups 2, 3 and 4 were made simultaneously, and splenectomized animals, groups 2 and 3 were donors, respectively, for the animals of groups 3 and 4. In group 4 the spleen was preserved and the animals received implants from the spleens of rats from group 3. The regeneration of splenic tissue was evaluated by macroscopic and microscopic analyzes of the grafts and own spleens, as well as with measurements of VLDL, HDL, LDL, total cholesterol and triglycerides. Results Results ResultsResults Results: after 120 days, Group 4 showed levels of total cholesterol and LDL lower than the other groups. Group 1 had higher levels of lipids. Conclusion Conclusion Conclusion Conclusion Conclusion: The technique of double spleen was effective in the control of lipid metabolism, corroborating the function of the spleen as a reserve of lipids.

<strong>Neste artigo, foram utilizadas técnicas de gerência de materiais no planejamento de ressuprimento de materiais no almoxarifado de uma empresa do setor elétrico, cujo processo de aquisição se dá aos moldes de compras públicas. Este estudo objetivou analisar e propor melhorias ao processo de ressuprimento de materiais, de modo que a empresa tivesse suas solicitações atendidas com redução de capital imobilizado em estoques e aumento da eficiência em seus processos de aquisição de materiais. Para tanto, utilizou-se de uma análise do histórico de Requisições de Compras (RC), Atas de Registro de Preço (ARP) e Documentos Formais de Compras (DFC) que serviram de base para a coleta de dados. A partir desses dados, juntamente com o mapeamento do processo de compras, foram sugeridas alterações na forma de inclusão de novos dados no ERP (Enterprise Resource Planning) da empresa, além de definições de famílias de materiais e a criação de ferramentas para geração de sugestões de RC e controle de ARP. Além disso, foi sugerido outro modelo de reposição de estoques para a empresa. A fim de verificar a eficácia do sistema proposto, foi apresentada uma avaliação comparativa entre a situação atual de alguns itens existentes nos estoques e um contexto potencial, obtido com a implementação das melhorias propostas nesta pesquisa. Como resultado, concluiu-se que o sistema proposto apresentaria vantagens significavas em relação ao sistema atual da empresa que considera outras possíveis formas de aquisição contempladas na administração pública.</strong>

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