PURPOSE:To evaluate the effects of copaiba oil on the correction of abdominal defect treated with the use of polypropylene/ polyglecaprone mesh in rats.
METHODS:A defect in the abdominal wall was created and corrected with polypropylene/polyglecaprone mesh in 36 rats. They were randomly distributed into three groups: control, copaiba by oral administration (gavage) and copaiba oil dip in the mesh. Euthanasia was performed after seven, 14 and 21 post-operative days. The healing process was analyzed regarding the meshes and macroscopic and microscopic aspects.
RESULTS:All animals had abdominal adhesions, which were smaller in the copaiba (gavage) group (p<0.05). In microscopy, all animals had an acute inflammation stage and the inflammatory response was best characterized by foreign body-type granulomas around the mesh fragments, which was not found in the mesh fragments within the copaiba dip group. There was a greater area of necrosis and fibrosis in the copaiba dip group compared to the control group (p<0.05). The copaiba (gavage) group had a greater quantity of collagen fibers compared to the control group.
CONCLUSION:Copaiba oil administered by gavage decreased the amount of abdominal adhesions, besides accelerating the process of collagen fibers formation, without damages within the early stages of healing. However, when used by dip directly on the mesh, it had corrosive effects compromising the healing process of the abdominal wall.
Objective: To evaluate the influence of the understanding of brain death in relation to organ donation in patients from the Marco School Health Center, which is linked to the Universidade do Estado do Pará.Methods: A total of 136 patients were interviewed based on a research protocol. The interview results were subsequently analyzed with regard to the understanding of brain death and organ donation in addition to the collection of sociodemographic data.Results: The majority of patients were female and were in favor of organ donation, with a mean age of 39 years being observed. Only 19.9% of the patients understood the meaning of brain death, and 85.3% believed that physicians may be mistaken in confirming the status of brain death of a patient, while 18.4% trusted the diagnosis of brain death. A statistically significant (p < 0.01) correlation was observed between the degree of confidence in the diagnosis of brain death and the person's agreement to donate his/her organs after death.Conclusion: The majority of the population under study did not understand the meaning of brain death and had a low degree of confidence in the diagnosis of brain death. This lack of understanding and confidence negatively influences the desire to donate organs.
Vascular anastomoses are common procedures and are performed by most surgeons. Training is primarily conducted in human beings, which violates current ethical principles. This is because current training models are expensive and in short supply. This study was designed to investigate the feasibility of three vegetable models of vascular anastomosis. Five units each of scallions, green beans, and yardlong beans were used. An end-to-end anastomosis was attempted with each specimen. Anastomoses were only successful in green beans and yardlong beans. Since they are narrower, the yardlong beans are the most similar to human vessels.Keywords: surgery; medical education; training; training by simulation.
ResumoAnastomoses vasculares são procedimentos comuns realizados por grande parte dos cirurgiões e cujo treinamento ocorre principalmente em seres humanos, contrariando os princípios éticos vigentes. Esse fato se deve, sobretudo, à carência e ao alto custo relacionados aos atuais modelos de treinamento. Assim, este estudo visa avaliar a viabilidade de três vegetais para a realização de anastomoses vasculares. Foram utilizadas cinco unidades de cebolinha, vagem e feijão-verde. Em cada uma tentou-se realizar uma anastomose término-terminal. Conseguiu-se a realização da anastomose apenas na vagem e no
The very high rates of poorly completed medical certificates of death highlights a significant failure in the medical schools' curriculum, as well as a lack of continuing medical education programs addressing such topic of paramount importance. The results demonstrated neglect or lack of knowledge on the pathophysiology of diseases by physicians.
Dentre os conceitos relacionados à terminalidade da vida, encontram-se a distanásia e a ortotanásia. Distanásia significa a obstinação terapêutica para adiar a morte iminente. Ortotanásia significa morte em seu processo natural, não prolongando o tratamento. Este estudo objetivou analisar a percepção de familiares de pacientes internados acerca da ortotanásia e distanásia, avaliando a alternativa mais aceita. Trata-se de estudo transversal e observacional, no qual foram entrevistados 190 familiares por meio de questionário padronizado contendo perguntas sobre aspectos sociais e conhecimento da temática. A maioria (64,2%) manifestou preferência pela distanásia como conduta para seu familiar. Entre 122 participantes que desconheciam o significado de "estado terminal", 85,2% optariam pela distanásia. Porém, entre os que conheciam o significado, 70,9% optariam pela ortotanásia. O estudo indica a necessidade de trazer o tema para discussão da sociedade, sensibilizando-a a entender implicações individuais e coletivas do prolongamento da vida em situação de sofrimento.
Background. Smartphone cameras are continuously improving. The present study aimed to evaluate the possibility of using smartphones' magnification system to perform microanastomosis in rats. Methods. Fifteen rats were randomly divided into 3 groups, according to the magnification system used: Microscope, iPhone 7 smartphone, and Galaxy S7 smartphone. In the microscope group, a DFVasconcelos microsurgery microscope was used. In both smartphone groups, the magnifications systems were connected to a 55-inch television through the mirror function. Animals in both groups underwent femoral artery anastomosis in the right forepaw and femoral nerve neurorrhaphy in the left hindleg. The body weight, arterial and nerve caliber, and anastomosis time and patency were immediately analyzed. Results. No significant differences were observed between the groups regarding body weight, arterial, or nerve caliber. The smartphones did not provide a sufficient quality of image for an adequate identification of the arterial walls. Therefore, neither arterial anastomosis nor neurorrhaphy could be completed, even after 3 hours of surgery. The first steps toward anastomosis or raffia were performed with difficulty. Conclusion. The current video resolution and lack of stereoscopic image of available smartphones is not sufficient to perform video-assisted anastomosis of femoral arteries or nerves.
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