Objective:to evaluate the quality of life of adult patients with hematological cancer comparing Hematopoietic Stem Cell Transplantation modalities during the first year of treatment. Method:this is an observational and longitudinal research with 55 participants. Data collection was performed in six steps: before transplantation, pancytopenia, before hospital discharge, after 100, 180 and 360 days, in a reference hospital in Brazil for this treatment. The international instruments Quality of Life Questionnaire - Core 30 and Functional Assessment Cancer Therapy - Bone Marrow Transplantation were validated and translated into Portuguese (Brazil). Results:the mean age of participants was 36 years, 65% (n = 36) had leukemia diagnosis and 71% (n = 39) had undergone allogenic transplantation. In the Quality of Life Questionnarie - Core30 instrument, the pain symptom was significant between the first and second stages, and loss of appetite between the third and fourth stages, both in the allogenic group. In the Functional Assessment Cancer Therapy - Bone Marrow Transplantation, the functional well-being domain was significant between the third and fourth stages, also in the allogenic group. Conclusions:although the aggressiveness of treatment affects quality of life, patients consider it satisfactory after the first year. There are few significant differences between autologous and allogenic patients, and both groups have recovered in the course of the process.
RESUMO Objetivo: Avaliar os efeitos da intervenção acupressura auricular na qualidade de vida de mulheres com câncer de mama em tratamento quimioterápico, em comparação com as que não utilizaram a intervenção. Método: Ensaio clínico randomizado com 54 mulheres, acompanhadas semanalmente por 12 semanas, sendo 27 no grupo intervenção, que utilizou esferas de cristal em seis acupontos (shenmen, rim, estômago, cárdia, tronco cerebral e endócrino), e 27 no grupo controle. A qualidade de vida foi mensurada em cinco etapas; a primeira, antes de iniciar a intervenção e as seguintes, a cada três semanas, com os instrumentos Quality of Life Questionnaire Core 30 e Quality of Life Questionnaire – Breast Cancer BR-23. Resultados: Houve melhora em todos os domínios relacionados à qualidade de vida; porém, a significância foi para náusea, vômito e sintomas da mama no grupo intervenção. Conclusão: Acupressura auricular mostrou-se como um método seguro, eficaz, de baixo custo, sem efeitos colaterais, facilmente aplicável por enfermeiros treinados. Pode ser recomendada como terapia complementar no tratamento do câncer de mama para melhorar a qualidade de vida dessas mulheres. A pesquisa foi cadastrada no Registro Brasileiro de Ensaios Clínicos com o código n° RBR-36zcfg.
Objective To reflect on the understanding of financial toxicity, as an adverse event of cancer diagnosis and treatment, and its implications on the quality of life of these patients. Method Reflexive study, based on the international literature about the concept of financial toxicity and its relationship with quality of life. Results Financial toxicity is related to the financial difficulties associated with cancer and its treatment, which occur in the lives of patients and family members. Its consequences include: possible worsening of the clinical symptoms, indebtedness, loss of professional opportunities, changes in family habits and decline in quality of life. Final considerations Measures to minimize financial toxicity should also be a concern of the state and be part of the therapeutic itinerary of cancer patients. Dialogue can become an essential tool for the health team to clarify the therapeutic options and their costs. This attitude shows respect and preserves the patient’s autonomy, which can minimize the feeling of helplessness in the face of the disease.
Objective: to evaluate the quality of life of adult patients with hematologic cancers undergoing hematopoietic stem cell transplantation in the first six months and comparing the transplant modalities.Method: an observational longitudinal study with 55 participants followed during pre-transplantation, after 100 days, and after 180 days in a reference teaching hospital for this treatment in Brazil. Two international instruments were used for the evaluation, both validated and translated into Portuguese (Brazil): The Quality of Life Questionnaire-Core 30 and the Functional Assessment Cancer Therapy-Bone Marrow Transplantation. Results:The results showed that the average age of the participants was 36 years old; 65% (n=36) had a diagnosis of leukemia, and 71% (n=39) underwent allogeneic transplantation. Regarding the Quality of Life Questionnaire-Core 30 instrument, social function and fatigue were significant results, while the functional well-being and treatment outcome evaluation index for the Functional Assessment Cancer Therapy-Bone Marrow Transplantation questionnaire had significant domains between the first and the second stage.Conclusions: despite transplantation being a complex and aggressive treatment, it can be noticed that patients generally perceive their quality of life as satisfactory throughout the therapeutic process. The findings of the study show that a significant portion (69% of patients) recover their quality of life after the first six months of treatment. DESCRIPTORS: QUALIDADE DE VIDA NOS PRIMEIROS SEIS MESES PÓS-TRANSPLANTE DE CÉLULAS-TRONCO HEMATOPOÉTICAS CALIDAD DE VIDA EN LOS PRIMEROS SEIS MESES POST-TRANSPLANTES DE CÉLULAS-TRONCO HEMATOPOÉTICAS RESUMENObjetivo: evaluar la calidad de vida de los pacientes adultos con cáncer hematológico sometidos al transplante de células madre hematopoyéticas en los primeros seis meses y comparar entre las modalidades de trasplante.Método: estudio observacional, longitudinal, con 55 participantes, acompañados en las etapas pre-trasplante, después de 100 días y después de 180 días, en un hospital de enseñanza, referencia en Brasil para este tratamiento. Para la evaluación se utilizaron dos instrumentos internacionales, ambos validados y traducidos a la lengua portuguesa (
Objective: to evaluate the impairment of social and emotional domains of hospitalized patients undergoing hematopoietic stem cells transplantation. Method: an observational, longitudinal study with 25 participants evaluated in the period of pre-transplant, pancytopenia and pre-hospital discharge between September 2013 and September 2014, in a reference hospital for this treatment modality in Brazil. Two international instruments were used, both of which translated and adapted to Portuguese (Brazil): Quality of Life Questionnaire-Core 30 and Functional Assessment Cancer Therapy -Bone Marrow Transplantation. Results: patients have shown a statistically signifi cant decrease in the social domain, and stability of the emotional function along the course of treatment. Conclusion: hematopoietic stem cell transplantation changes the social function of patients with hematologic cancer during hospitalization stage. Thus, patients should receive guidance addressing the social domain in order that it can be less affected.
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