Qualidade De Vida Nos Primeiros Seis Meses Pós-Transplante De Células-Tronco Hematopoéticas

Abstract

Objective: to evaluate the quality of life of adult patients with hematologic cancers undergoing hematopoietic stem cell transplantation in the first six months and comparing the transplant modalities.Method: an observational longitudinal study with 55 participants followed during pre-transplantation, after 100 days, and after 180 days in a reference teaching hospital for this treatment in Brazil. Two international instruments were used for the evaluation, both validated and translated into Portuguese (Brazil): The Quality of Life Questionnaire-Core 30 and the Functional Assessment Cancer Therapy-Bone Marrow Transplantation. Results:The results showed that the average age of the participants was 36 years old; 65% (n=36) had a diagnosis of leukemia, and 71% (n=39) underwent allogeneic transplantation. Regarding the Quality of Life Questionnaire-Core 30 instrument, social function and fatigue were significant results, while the functional well-being and treatment outcome evaluation index for the Functional Assessment Cancer Therapy-Bone Marrow Transplantation questionnaire had significant domains between the first and the second stage.Conclusions: despite transplantation being a complex and aggressive treatment, it can be noticed that patients generally perceive their quality of life as satisfactory throughout the therapeutic process. The findings of the study show that a significant portion (69% of patients) recover their quality of life after the first six months of treatment. DESCRIPTORS: QUALIDADE DE VIDA NOS PRIMEIROS SEIS MESES PÓS-TRANSPLANTE DE CÉLULAS-TRONCO HEMATOPOÉTICAS CALIDAD DE VIDA EN LOS PRIMEROS SEIS MESES POST-TRANSPLANTES DE CÉLULAS-TRONCO HEMATOPOÉTICAS RESUMENObjetivo: evaluar la calidad de vida de los pacientes adultos con cáncer hematológico sometidos al transplante de células madre hematopoyéticas en los primeros seis meses y comparar entre las modalidades de trasplante.Método: estudio observacional, longitudinal, con 55 participantes, acompañados en las etapas pre-trasplante, después de 100 días y después de 180 días, en un hospital de enseñanza, referencia en Brasil para este tratamiento. Para la evaluación se utilizaron dos instrumentos internacionales, ambos validados y traducidos a la lengua portuguesa (

Bone marrow transplantation and adverse reactions present in post-transplantation patients: a literature review

“…In a study conducted by MARQUES et al (2017), patients presented symptoms of fatigue, insomnia and loss of appetite, interfering in physical, emotional and social functions, correlating the side effects of treatment causing an impact on the quality of life of patients. The loss of appetite had greater intensity in autologous transplants in the pretransplant period, allogeneic patients presented in the post-100-day stage.…”

“…The loss of appetite had greater intensity in autologous transplants in the pretransplant period, allogeneic patients presented in the post-100-day stage. The clinical alteration in autologous and allogeneic patients were similar in quality of life, however, there is a lack of materials that objective to analyze the differences in quality of life among patients undergoing this therapy (MARQUES et al, 2017).…”

“…However, after performing the transplant, immunity weakens due to the stages that patients are submitted, in the period of pancytopenia, when all blood cells decrease red blood cells, platelets and leukocytes, the patient becomes quite fragile subject to possible infections, organ involvement, in addition to psychological problems. For transplantation to occur it is necessary to destroy the bone marrow, with the following reconstitution of the same that can last for years or months, it will depend on the cell line (MARQUES et al, 2017).…”

Transplante de medula óssea - Prevenção de infecção de cateter central

“…Segundo estudo 21 , os autores abordam sobre dimensionamento e cooperação entre as equipes multidisciplinares durante as fases do procedimento, e destaca a enfermagem como sendo o profissional com mais acesso ao paciente para prestar cuidados, além de desempenhar outras funções, como: supervisionar as atividades e educação em saúde. Para isso, exigem do enfermeiro conhecimentos técnico científico, competências e habilidades para detectar e intervir em reações adversas.…”

Enfermagem em Transplante de Células Tronco Hematopoiéticas: estudo bibliométrico

“…Essa fala é endossada por Marques et al (2017), para quem o apoio familiar é substancial para o paciente que se submete ao TCTH. O autor enfatiza que é fundamental para esse paciente ter a certeza de que não está sozinho para enfrentar todas as dificuldades relacionadas ao tratamento, o qual, por sua vez, não é instantâneo, mas complexo, intenso e lento.…”