2005
DOI: 10.1590/s0365-05962005000100011
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Pioderma gangrenoso e artrite reumatóide: relato de caso

Abstract: The case is described of a 15-year-old patient that presented several pyoderma gangrenosum lesions 16 months before onset of rheumatoid arthritis manifestations. There was an excellent response to therapeutics using clofazimine. Keywords: Arthritis; Arthritis, reumatoid; Clofazimine; Clofazimine/therapeutic use; Pyoderma gangrenosum/drug therapy; Pyoderma gangrenosum/therapy; Case report. Resumo

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Cited by 10 publications
(12 citation statements)
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References 9 publications
(15 reference statements)
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“…In up to 25% of cases of PG, the appearance of new lesions may have been triggered by trauma such as insect bites, intravenous injections or biopsy, a phenomenon known as pathergy. 6,7 The present study reports on a case of extensive PG of difficult diagnosis in which an excellent response to treatment was achieved with corticoids, initially associated with clofazimine and dapsone and, later, with azathioprine.…”
Section: -4mentioning
confidence: 89%
“…In up to 25% of cases of PG, the appearance of new lesions may have been triggered by trauma such as insect bites, intravenous injections or biopsy, a phenomenon known as pathergy. 6,7 The present study reports on a case of extensive PG of difficult diagnosis in which an excellent response to treatment was achieved with corticoids, initially associated with clofazimine and dapsone and, later, with azathioprine.…”
Section: -4mentioning
confidence: 89%
“…Em monoterapia: buloses (quando há restrição ao uso de corticosteroide) 48,49 , pioderma gangrenoso; 50 Combinada com outras drogas: vasculites, colagenoses.…”
Section: Micofenolato Mofetilunclassified
“…1-3 É uma dermatose inflamatória crônica e recidivante, relativamente infrequente, não infecciosa, idiopática, de caráter destrutivo local, geralmente associada a outras afecções locais ou sistêmicas. 4 É mais frequente em adultos, mas crianças também podem ser afetadas em raros casos. 2 A faixa etária mais acometida é a dos 25 aos 55 anos, mais frequente em mulheres.…”
Section: Introductionunclassified
“…Disfunção neutrofílica, especialmente defeitos na quimiotaxia, tem sido sugerida como possível causa do PG. 1,2,4 O PG apresenta acometimento predominantemente dos membros inferiores, mas pode afetar também tronco, abdome e face. 2 Clinicamente, observa-se a presença de pústulas hemorrágicas, nódulos dolorosos ou múltiplas vesicopústulas.…”
Section: Introductionunclassified
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