Methyladenosine modifications are the most abundant RNA modifications, including N6-methyladenosine (m6A), N1-methyladenosine (m1A), and 2’-O-methyladenosine (m6Am). As reversible epigenetic modifications, methyladenosine modifications in eukaryotic RNAs are not invariable. Drastic alterations of m6A are found in a variety of diseases, including cancers. Dynamic changes of m6A modification induced by abnormal methyltransferase, demethylases, and readers can regulate cancer progression via interfering with the splicing, localization, translation, and stability of mRNAs. Meanwhile, m6A, m1A, and m6Am modifications also exert regulatory effects on noncoding RNAs in cancer progression. In this paper, we reviewed recent findings concerning the underlying biomechanism of methyladenosine modifications in oncogenesis and metastasis and discussed the therapeutic potential of methyladenosine modifications in cancer treatments.

DCE-MRI is an accurate technique for the assessment of spinal tumor vascularity, which may have a potential value in the decision-making of preoperative embolization.

Northwest China includes Xinjiang Ugyur Autonomous Region, Qinghai Province, Gansu Province, Ningxia Hui Autonomous Region and Shaanxi Province, covering 308×10 4 km 2 . It is located in the warm-temperate zone and the climate is arid or semi-arid. Precipitation is very scarce but evaporation is extremely high. The climate is dry, the water resources are deficient, the eco-environment is fragile, and the distribution of water resources is uneven. In this region, precipitation is the only input, and evaporation is the only output in the inland rivers, and precipitation, surface water and groundwater change with each other for many times, which benefits the storage and utilization of water resources.The average precipitation in this region is 232 mm, the total precipitation amount is 7003×10 8 m 3 /a, the surface water resources are 1891×10 8 m 3 /a, the total natural groundwater resources are 1150×10 8 m 3 /a, the total available water resources are 438×10 8 m 3 /a, and the total water resources are 1996×10 8 m 3 /a and per capita water resources are 2278 m 3 /a. The water resources of the whole area are 5.94×10 4 m 3 /(a.km 2 ), being only one-fifth of the mean value in China. Now, the available water resources are 876×10 8 m 3 /a, among which groundwater is proximate 130×10 8 m 3 /a.

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The research on the present situation of soil and water development and utilization in Shiyang River Basin shows that water resources and eco-environment situation in this area are near the edge of collapse. Since the water crises occurred in the 1970s, problems caused by continuous decrease of water resources have been becoming serious year by year and eco-environment crisis occurred as a consequence. Up to now, 10 380ha of irrigated lands have been abandoned due to sand coverage and water shortage in the basin. Ground water was over exploded in Wuwei and Minqin because of water shortage. Ground water table in many places dropped under 5m (which is the ecology water table level), thus about 3000ha ofElaeagnus angustifolia forest come to dead and another 5800ha become feeble, and wind-drift sand near the oasis become alive. According to the current situation, if water utilization scope was not enlarged, a water transfer volume of600x 10hn3/a from other areas will be suitable to keep water resources and eco-environment safety in the basin, and also 70x 106m3/a will be left as spare water. Under this condition the water resources and eco-environment of the basin can reach the critical safety line of 2.032x 109m3/a; or if 180x 106m 3 of water can be transferred from other areas, the water resources can reach the safety warning line of 1.732× 10~m3/a.

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The hot corrosion behavior of Yb 2 Si 2 O 7 bulk exposed to NaVO 3 was investigated at 500-900°C. Results indicated that the hot corrosion reaction could occur at 500°C, the corrosion products were composed of YbVO 4 and SiO 2 at 500-900°C. The content of YbVO 4 and SiO 2 in the corrosion product at 500°C was small and the crystal size of YbVO 4 was fine. As temperature increased, a continuous and dense corrosion layer could be formed on the bulk surface, which prevented the hot corrosion reaction from occurring dramatically. The hot corrosion reaction products mainly consisted of rod-shaped YbVO 4 beyond 600°C. Since the corrosion reaction driving force increased with temperature, the rod-like YbVO 4 crystals tended to go from slender to plump; moreover, both ends changed from irregular lamination to regular quadrangular pyramid shape; also SiO 2 crystals partly changed from flocculent to ellipsoid shape. The hot corrosion mechanisms of Yb 2 Si 2 O 7 bulk exposed to NaVO 3 at 500-900°C were investigated based on the corrosion products.