Low Quality Assurance in Pharmacy Award Ipilo Gorontalo include pharmaceutical, security, procurement, storage, and distribution or drug delivery, drug management, on a prescription drug services, drug information services, as well as drug development, medicinal materials and traditional medicine. The impact of the implementation of activities in the pharmacy pharmacy services Anugerah Ipilo errors may occur treatment (medication errors) in the service process. Quality Assurance (QA) is one dimension that is used in the measurement of quality of service, where the application of QA in pharmacies Ipilo Award aims to provide quality assurance of pharmaceutical products and the quality of services provided to patients. This research is descriptive, the source of primary data obtained from the questionnaires with QA standard indicator framework on pharmaceutical services in pharmacies Anugerah Ipilo. The assessment results then classified based on criteria appropriate, relatively appropriate and not appropriate. The results showed that the Quality Assurance (Quality Assurance) on the quality of the equipment and the safety assurance of Pharmaceutical Services in Pharmacy Award Ipilo there are seven questions (70%) had a very good criteria, three questions (30%) had a good criterion. Quality Assurance (Quality Assurance) on the Process of Pharmaceutical Services in Pharmacy Award Ipilo there are 4 questions (40%) had a very good criteria, one question (10%) had a pretty good and 5 questions (50%) had less good. Pharmacies merely focused on the administration and management of medication alone is not the overall pharmacy services, in addition because the pharmacy Anugerah Ipilo prefer the function of the economy (business) rather than its social function, which pharmacies are required to gain / profit in business.
A recent outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease also called Coronavirus disease 2019 in China, has rapidly spread to other countries of the world. The medical and scientific communities are working tirelessly to produce a vaccine due to the lethal nature of this virus. COVID-19 is a novel virus that requires immediate emergency therapy, thereby leading to massive fear of infection, social problems in the community, and an increase in the number of infected people. Therefore, scientists and researchers need to determine the epidemiological cases of the virus, such as its mode of transmission, effective preventive measures, and the nature of the life cycle. In addition, there need to be current literature advances in diagnostic development such as reverse transcription polymerase chain reaction (RT-PCR), computed tomography san (CT-Scan), ELISA as well as clinical researches on modern and herbal drugs for the treatment of infected patients. This treatment technique is classified from antiviral drugs such as entry, replication, nucleosides, nucleotides, and protease inhibitors, along with the use of heterocyclic drugs, monoclonal antibodies therapy, vaccine development and herbal formulations that have been pre-clinically tested in vitro and molecular docking. Chemical drug molecules with prospective applications in the treatment of COVID-19 have been included in this review.
Off-label drugs can be interpreted as drugs that are used not in accordance with drug information, distribution permits and sales licenses from the Marketing Authorization (MA) related to indications, age, dosage, route of administration and contraindications. The use of off-label drugs in children occurs because of incomplete data on pharmacokinetics, pharmacodynamics and side effect of a drug. It is because clinical research in children is quite difficult and not in accordance with research ethics and morals, so it has the potential to cause errors in treatment and unwanted drug reactions. This study aims to describe the use of off-label drugs in hospitalized pediatric patients at RSUD of Dr. M.M Dunda Limboto, Gorontalo District, Gorontalo Province. This is an obsevational study using cross sectional design and retrospective data collection. The sampling technique applies a purposive sampling technique with a total of 155 patiens who meet the inclusion criteria during the January-June 2020 period. The finding shows that from 155 patient medical records, there are 172 (16,51%) off-label drug used with a total of 1042 drugs. The off-label drugs used in the indication category are 64,53%, the off-label drugs used in dose category are 17,44%, the off-label drugs used in age category are 14,53%, the off-label drugs used in route of administration category are 3,49% and the off-label drugs used in contraindictions category are not found. The are the most off-label drugs used in each category, including domperidone (off-label in indications and dose), rhinofed (off-label in age) and salbutamol (off-label in route of administration).
Hypertension is a disease that continues to increase every year, where the keys to success for its treatment are selection and use of the drugs. The treatment failure occurred if the selection and use of medication are inappropriate with the condition of patients followed by DRPs. Unresolved hypertension can cause heart attack, kidney failure and stroke. The research aimed to identify DRPs at hypertension patients with or whitout comorbidity reviewed from the drug without indication, indication without drug, high doses, low doses, and drug interaction. The research was non-experimental descriptive research which applied cross-sectional design by collecting data through a retrospective at hypertension with or without comorbidity at Multazam Hospital of Gorontalo City for January-December 2018 periods. The samples were selected by purposive sampling and obtained 79 patients who were qualified as samples. The obtained data were analyzed with univariate. The finding of research showed that the use of medication at hypertension patient with or without comorbidity at Multazam Hospital of Gorontalo City for January-Desember 2018 periods based on five categories were drug without indication was 3.08%, indication without drug was 33,84%, high doses was 27,70%, low doses was 4,62% and drug interaction was 30,76%. The identification of DRPs of use of hypertension medication with or without comorbidity at Multazam Hospital of Gorontalo City for January-December 2018 periods was categorized good.
An emergency kit is life-saving drug storage that is immediately required for helping patients with a sudden decline in health status. Therefore, the management of an emergency kit should be taken into concern. This qualitative descriptive research is devoted to determining the management of the emergency kit (trolley) from the aspects of recording and reporting, arrangement, human resources, facilities, and infrastructure in Regional Public Hospital RSUD Hasri Ainun Habibie in 2019. The obtained data were analyzed based on the Regulation of the Minister of Health Number 72 of 2016 Concerning Standards of Pharmaceutical Services in Hospitals and the Standard Operating Procedures of the hospital mentioned earlier. Further, this study involved pharmacy staff as the responsible person of the Trolley and Emergency Trolley themselves as the sample. The results indicate that the wards, in terms of the recording and reporting processes, have not reached good management. It is revealed that out of seven wards that provide emergency trolley, 100% of them have not fulfilled the sub-variable on recording the taking of emergency stocks in the aspect of recording and reporting; 100% have not satisfied the sub-variable on using the key of disposable trolley in the aspect of arrangement; in the aspect of human resources, 100% and 50% have not met the sub-variables on the signing of the handover letter and trolley locking, respectively, and 25% have done the gradual stocks checking; in the aspect of facilities and infrastructure, 100% have not fulfilled the sub-variable on disposable lock document.
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