BACKGROUND: The presence of a coronavirus disease 2019 (COVID-19) vaccine is very important to produce an immune response that slows down the pandemic. AIM: This study aims to find out more about the perspective of the Indonesian people which is predicted to affect vaccine acceptance by the public. METHODS: Quantitative research was conducted using an online survey via a Google form. The survey was conducted from January to February 2021. RESULTS: There were 225 respondents. The attitude of the community towards the COVID-19 vaccination program, almost all respondents know the free vaccination program (94.4%) and know the purpose of the program (91.8%). There were 23% of respondents who felt that after being vaccinated they would be free from COVID-19 infection and 2.4% stated that they no longer needed to apply health protocols after being vaccinated. There were 8.2% who did not agree with the reasons they did not know its effectiveness, were worried about the side effects and were unsure about the safety of the COVID-19 vaccine. CONCLUSION: In general, self-confidence, comfort, calculation of benefits versus disadvantages, and shared responsibility, influence a person’s decision to refuse or accept the vaccine.
The bacteria Staphylococcus aureus are round bacteria that are shaped like a cocci, and are Gram-positive. These bacteria can be found on the skin, genitals, nasal cavity, mouth and around the anus. One of the pharmaceutical products that can maintain skin health and protect the skin is soap. The leaves of noni (M. citrifolia L.) contain various compounds such as flavonoids, tannins, saponins, alkaloids, and triterpenoids which are capable of being antibacterial. This study aims to make a liquid soap formulation from M. citrifolia L. leaf extract and its activity as an antibacterial to S aureus. The leaves of M. citrifolia L. were extracted using 96% ethanol solvent by maceration method until a thick extract was obtained. Soap formulations are made with a concentration of 20% 40% and 60%. Evaluation of soap quality includes organoleptic test, high foam test and pH test. The method of antibacterial testing is carried out in vitro by means of well diffusion. The results on the quality test of the liquid soap formulation showed that the pH and height of the foam had good results and had met the SNI 1996 Standards. From the results showed that formulation III with an extract content of 60% had a large antimicrobial activity with a value of 16.83 mm which was categorized as strong. In positive control (Dettol) 60% antimicrobial activity showed a value of 14.83 mm. The results of statistical tests were carried out by One-Way ANOVA analysis followed by LSD analysis Post hoc, liquid soap extract of M. citrifolia L. had greater antimicrobial potential than the positive control (Dettol).
Antioxidants are chemical compounds that donate one or more electrons to free radicals to inhibit free radical reactions. One of the potential antioxidant sources is gandaria fruit (Bouea Macrophylla Griff). This research aims to determine the antioxidant activity and vitamin C content of the gandaria fruit extract. Gandaria fruit was macerated with ethanol as a solvent. Furthermore, the rotated extract was carried out for the phytochemical screening. The results of the phytochemical screening of the gandaria fruit extract showed a positive of flavonoids, terpenoids, tannins, saponins, and phenolics. The gandaria fruit extract was tested for antioxidants and quantitative analysis of vitamin C levels to obtain IC50 values and vitamin C levels using spectrophotometry UV-Vis at a wavelength of 517nm with vitamin C as a positive control. The results of spectrophotometric measurements revealed that the gandaria fruit extract had an IC50 value of 5.72 g/ml, and vitamin C had an IC50 value of 2.260 g/ml, indicating that the gandaria fruit extract and vitamin C had very strong antioxidants. The value of vitamin C levels was 0.526 mg.
The bacteria that cause infections that can lead to high morbidity and mortality, the bacterium Pseudomonas aeruginosa. Bangle has a pharmacological activity as antibacterial, laxative, pancreatic lipase inhibitor, and protect cells from damage caused by oxidative stress. The purpose of this study are: to know the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Can be efficacious as an antibacterial and knowing Minimal Inhibitory concentration (MIC) of the extracts of leaves bangle against Pseudomonas aeruginosa. Tests on the leaf extracts for antibacterial activity against Pseudomonas aeruginosa bangle made by the method of Kirby Bauer and solvents used are DMSO. Test solution with a concentration of leaf extract bangle 200, 400, 600, 800 and 1,000 ppm, the positive control solution (ciprofoxacin) and the solution negative control (DMSO). The results showed that the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Are flavonoids, saponins, tannins, alkaloids and steroids. Value Minimum Inhibitory Concentration (MIC) of ethanol extract of the leaf bangle S bacteria Pseudomonas aeruginosa is a concentration of 40 % with an average diameter of 5.44 mm inhibitory. MIC extract ethanol extract of leaf bangle belonging to the bacterial activity that is strong enough..
Indonesia merupakan negara tropis dengan dua musim yaitu musim kemarau dan musim penghujan. Dimusim penghujan merupakan waktu untuk penyebaran penyakit demam berdarah dengue (DBD) oleh nyamuk Aedes aegypti. Kecombrang sudah lama digunakan sebagai bahan pangan dan bahan obat. Bagian bunga, daun, batang, dan rimpang kcombrang mengandung senyawa alkaloid, saponin, tanin, fenolik, flavonoid, triterpenoid, steroid, dan glikosida. Daun beluntas mengandung tannin dan alkaloid, selain itu juga mengandung flavonoid, fenol, saponin, dan minyak atsiri. Tujuan penelitian ini ialah untuk mengetahui efektvitas ekstrak daun kecombrang (Etlingera elatior) dan daun beluntas (Pluchea indica) sebagai biolarvasida terhadap larva nyamuk A.aegypti. Manfaat dari penelitian ini yaitu dapat mengetahui potensi dari ekstrak etanol daun kecombrang dan daun beluntas sebagai biolarvasida untuk A.aegypti. Penelitian ini diharapkan dapat digunakan sebagai sumber pengetahun dari daun kecombrang dan daun beluntas sebagai bahan biolarvasida. Bahan yang digunakan menggunakan air sumur, daun kecombrang, daun beluntas, larva nyamuk A.aegypti, dan ethanol 96%. Penelitian ini merupakan penelitian eksperimental dengan menggunakan rancangan acak lengkap (RAL) dengan tujuh perlakuan dan ulangan sebanyak empat kali. Pengamatan dilakukan setelah 24 jam dengan cara menghitung larva yang mati dan dinyatakan dalam persen kematian. Selanjutnya hasil dianalisis menggunakan analisis probit untuk mengetahui nilai LC50. Hasil dari penelitian ini yaitu ekstrak daun kecombrang (E.elatior) dan daun beluntas (P.indica) positif mengandung alkaloid, flavonoid, terpenoid/steroid, dan tannin serta negatif mengandung saponin. Kesimpulan dari penelitian ini yaitu kombinasi dari kedua ekstrak ini memiliki potensi sebagai biolarvasida dengan nilai LC50 sebesar 910 ppm.
The purpose of this study was to determine the extracts of beluntas leaves (P. indica) and kecombrang leaves (E. elatior) that could be useful as antibacteria for Pseudomonas aeruginosa and Propionibacterium acnes and to determine the inhibition zone produced from extracts of beluntas leaves (P. indica) and kecombrang leaves (E. elatior) which is used as an antibacterial for P. aeruginosa and P. acnes. The results of this study indicate that the combined extract concentration has significantly different results in the combination treatment of beluntas and kecombrang leaves extracts which were tested on the test bacteria P. acnes producing an inhibition zone of 0 mm (negative control); 7.13 mm (combination of 5% extract concentration); 8.2 mm (combination of 10% extract concentration); 11.18 mm (combination of 50% extract concentration) and positive control clindamycin is 26.3 mm. The results of the test combination of the extract with the test bacteria P. aeruginosa there was no inhibition zone, except for the positive control of 12.1 mm chloramphenicol. Tujuan dari penelitian ini yaitu untuk mengetahui ekstrak daun beluntas (P. indica) dan daun kecombrang (E. elatior) dapat bermanfaat sebagai antibakteri Pseudomonas aeruginosa dan Propionibacterium acnes dan untuk mengetahui zona hambat yang dihasilkan dari ekstrak daun beluntas (P. indica) dan daun kecombrang (E. elatior) yang digunakan sebagai antibakteri P. aeruginosa dan P. acnes. Hasil dari penelitian ini menunjukkan bahwa pada konsentrasi kombinasi ekstrak memiliki hasil yang berbeda secara signifikan pada perlakuan kombinasi ekstrak daun beluntas dan kecombrang yang dilakukan uji pada bakteri uji P. acnes yang menghasilkan daya hambat berturut-turut sebesar 0 mm (kontrol negatif); 7,13 mm (kombinasi konsentrsai ekstrak 5%); 8,2 mm (kombinasi konsentrasi ekstrak 10%); 11,18 mm (kombinasi konsentrasi ekstrak 50%.) dan kontrol positif klindamisin 26,3 mm. Hasil dari pengujian kombinasi konsentrasi ekstrak dengan bakteri uji P. aeruginosa tidak terdapat zona hambat, kecuali pada kontrol positifnya yaitu kloramfenikol sebesar 12,1 mm.
The purpose of this study was to find out how students perceive online learning during this pandemic. This study uses a qualitative descriptive method consisting of data collection, data reduction, data presentation and drawing conclusions. The subjects of this study were active Pharmacy students of STIKes Salsabila Serang from semesters 2, 4, 6 and 8, totaling 376 respondents. The data in this study were obtained using a questionnaire instrument distributed through Google Form with a Likert scale from 1 to 5: 1 means strongly disagree and 5 means strongly agree. There are three aspects of questions in the questionnaire distributed, these aspects are 1) aspects of teaching and learning, 2) aspects of lecturer competence, and 3) aspects of facilities and infrastructure. Of the three aspects, aspect 1 is in the Medium category with an average perception value of 3.40, aspect 2 is in the high category with an average perception of 3.94, and aspect 3 is in the high category with an average perception of 3.85. Furthermore, from the results of the recapitulation of the percentage of respondents' answers as a whole, it can be concluded that in general, Pharmacy students at STIKes Salsabila Serang have high perception of online learning with a perception average value of 3.72. Tujuan penelitian ini adalah untuk mengetahui bagaimana persepsi mahasiswa terhadap pembelajaran secara daring di masa pandemi ini. Penelitian ini menggunakan metode deskriptif kualitatif yang terdiri dari pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Subjek penelitian ini adalah mahasiswa aktif STIKes Salsabila Serang pada prodi S1-Farmasi dari semester 2, 4, 6 dan 8 yang berjumlah 376 responden. Data dalam penelitian ini diperoleh dengan menggunakan instrument angket yang disebar melalui Google Form dengan skala likert dari 1 sampai 5: 1 berarti sangat tidak setuju dan 5 berarti sangat setuju. Terdapat tiga aspek pertanyaan yang ada pada angket yang disebar, aspek tersebut yaitu 1) aspek belajar mengajar, 2) aspek kompetensi dosen, dan 3) aspek sarana dan prasarana. Dari ketiga aspek tersebut, aspek 1 masuk dalam kategori Sedang dengan nilai rerata persepsi 3,40, aspek 2 masuk kategori tinggi dengan rerata persepsi 3,94, dan aspek 3 masuk kategori tinggi dengan rerata persepsi 3,85. Selanjutnya, dari hasil rekapitulasi persentase jawaban reponden secara keseluruhan dapat disimpulkan bahwa secara umum mahasiswa STIKes Salsabila prodi S1-Farmasi memiliki persepsi tinggi pada pembelajaran daring dengan persentase nilai rerata persepsi 3,72.
The level of Indonesian people's awareness of personal hygiene are still poor. One effective way to maintain a healthy body is to keep your hands clean. Hand sanitizer is one of the antiseptic ingredients in the form of a gel that is often used by the public as a practical hand washing medium. Determine consumer interest in the use of hand sanitizers in the Margahayu Raya Resident was the purpose of this research. This research was conducted using a questionnaire method that is distributed online. The sampling technique used a total sampling method with a total of 40 respondents. The method used to analyze consumer interest in The Use of Hand Sanitizers is descriptive analysis with the help of SPSS version 26 software. Based on the results of the study, it is stated that respondents have an interest in the use of hand sanitizers> 4 times a day, liquid / spray packaging, price < Rp. 25,000, information from social media, the hand sanitizer brand that is often used is Antis, and feels refreshing when used. Respondents are also very interested in using hand sanitizers to keep their hands clean and feel comfortable when it used. Tingkat kesadaran masyarakat Indonesia terhadap kebersihan diri masih sangat rendah. Salah satu cara yang sangat efektif untuk menjaga kesehatan tubuh adalah dengan menjaga kebersihan tangan. Hand sanitizer merupakan salah satu bahan antiseptik berupa gel yang sering digunakan masyarakat sebagai media pencuci tangan yang praktis. Tujuan dari penelitian ini yaitu untuk mengetahui minat konsumen terhadap penggunaan hand sanitizer di Komplek Margahayu Raya. Penelitian ini dilakukan menggunakan metode kuesioner yang disebar secara online. Teknik pengambilan sampel menggunakan metode total sampling dengan jumlah responden sebanyak 40 orang. Metode yang digunakan untuk menganalisis minat konsumen terhadap penggunaan hand sanitizer yaitu dengan analisis deskriptif dengan bantuan software SPSS versi 26. Berdasarkan hasil penelitian menyatakan bahwa responden memiliki minat terhadap penggunaan hand sanitizer sebanyak 4 kali dalam sehari, kemasan berbentuk cair/spray, harga < Rp. 25.000, media informasi dari media sosial, merk hand sanitizer yang sering digunakan antis dan rasa menyegarkan saat digunakan. Responden juga sangat tertarik dalam penggunaan hand sanitizer untuk menjaga kebersihan tangan dan rasa yang nyaman saat digunakan.
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