Aktivitas Ekstrak Daun Bangle (zingiber purpureum roxb.) Terhadap Pertumbuhan Bakteri Pseudomonas aeruginosa

Abstract

The bacteria that cause infections that can lead to high morbidity and mortality, the bacterium Pseudomonas aeruginosa. Bangle has a pharmacological activity as antibacterial, laxative, pancreatic lipase inhibitor, and protect cells from damage caused by oxidative stress. The purpose of this study are: to know the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Can be efficacious as an antibacterial and knowing Minimal Inhibitory concentration (MIC) of the extracts of leaves bangle against Pseudomonas aeruginosa. Tests on the leaf extracts for antibacterial activity against Pseudomonas aeruginosa bangle made by the method of Kirby Bauer and solvents used are DMSO. Test solution with a concentration of leaf extract bangle 200, 400, 600, 800 and 1,000 ppm, the positive control solution (ciprofoxacin) and the solution negative control (DMSO). The results showed that the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Are flavonoids, saponins, tannins, alkaloids and steroids. Value Minimum Inhibitory Concentration (MIC) of ethanol extract of the leaf bangle S bacteria Pseudomonas aeruginosa is a concentration of 40 % with an average diameter of 5.44 mm inhibitory. MIC extract ethanol extract of leaf bangle belonging to the bacterial activity that is strong enough..

In vitro Antibacterial Activity of Seribu kuman Leaf (Rhinacanthus nasutus (l.) Kurz) Extracts Against Staphylococcus aureus and Pseudomonas aeruginosa

“…Research by Noviyanto et al (2020) examined that bangle leaves (Zingiber purpureum roxb) at a concentration of 100% showed the most significant activity against the growth of P. aeruginosa bacteria with an inhibition zone of 10 mm (Noviyanto et al, 2020).…”

Inventarisasi Tanaman Berkhasiat Obat di Desa Muara Baru Kecamatan Kota Kayu Agung Kabupaten Ogan Komering Ilir (OKI)

“…Bangle mengandung saponin, flavonoid, minyak atsiri, tanin, steroid, triterpenoid, antioksidan seperti Vitamin C, vitamin E, karoten, dan senyawa fenolik. Berdasarkan hasil penelitian ekstrak rimpang bangle memiliki aktivitas farmakologi sebagai antibakteri, laksatif, inhibitor lipase pankreas, dan melindungi sel dari kerusakan akibat stress oksidatif oleh H2O (Noviyanto et al, 2020).…”

Ethnobotanical Study of Medicinal Plants in Maridan Village, Panajm Paser Utara District, East Kalimantan, Indonesia

“…The following table contains medicinal plant compounds which have been summarized from various sources: (Source: Shanbhag et al 2011;Arie et al, 2014;Amanah et al, 2018;Dharmayati. 2019;Essa et al 2020;Mufida and Puspitasari 2020;Noviyanto et al, 2020;Saputra, 2021);Fatikhurokhmah 2022;Nurhaini et al, 2022;Rosyida et al, The plant organs most widely used as medicine by the people of Maridan Village are the leaves.…”