Remote ischemic perconditioning was more effective reducing renal ischemia-reperfusion injury than administration of tramadol or association of both treatments.
The use of andiroba in topical form may be associated with reduced intensity of OM. Seek therapeutic alternatives to minimize the pain and suffering that these side effects cause cancer patients is an important scientific step.
Continuous versus interrupted suture technique in microvascular anastomosis in rats 1
1-Experimental SurgeryActa Cir Bras. 2017;32(9):691-696
AbstractPurpose: To compare the continuous and interrupted suture technique on femoral artery on rats after vessel repair and 14 days after. Methods: Twenty rats were operated randomly divided into two group matched according to the suture technique used: interrupted or continuous. We performed a femoral anastomosis on the right femoral artery. We analyzed weight, arterial caliber, anastomosis time and patency after vessel repair and 14 days after. Results: There was no significant difference between groups in the weight (p=0.64), diameter of the femoral artery (p=0.95) and patency (p=1.00). The time spent in the anastomosis was 451 seconds in the continuous group and 718 seconds in the interrupted group, presenting significant difference (p<0.01).
Conclusion:The continuous suture technique shows a similar patency rates than interrupted technique, however with a shorter time to perform the anastomosis.
IVPerconditioning associated to hypertonic saline solution on liver function improvement after ischemia/reperfusion injury 1
6-Experimental Surgery
949Perconditioning associated to hypertonic saline solution on liver function improvement after ischemia/reperfusion injury Ribeiro Júnior RFG et al. Acta Cir Bras. 2017;32(11):949-955
preparation, English version. V Graduate student, UEPA, Belem-PA, Brazil. Care of the animals, technical procedures, interpretation of data, manuscript preparation. VI MD, Graduated from Centro Universitário do Estado do Pará. Brazil. Care of animals, technical procedures, interpretation of data, manuscript preparation.
Background: Intensive care units (ICUs) admissions due to sepsis represent 2 to 11%. Although there are well stablished therapeutic available, it still is the major cause of death in most ICUs and the leading cause of acute kidney injury. The objective of this work was to evaluate the role of Aloe vera extract on survival rates and kidney histopathology of mice submitted to sepsis induced by cecal ligation and puncture.
Methods and Findings:Twenty six mice were distributed into four groups: Sham -surgery simulation (N=5); Control -Cecal ligation and puncture was performed (N=7); Aloe -Surgery simulation and treatment with Aloe vera extract (N=7); and Sepsis + Aloe -Cecal ligation and puncture was performed followed by treatment with Aloe vera extract (N=7). The animals were observed until death. Kidneys were analysed by histopathology. Kruskall-Wallis test was used to compare the histopathological results. Survival analysis was assessed by Kaplan-Meier statistics and compared using log rank test. A significance level of 5% was adopted. The survival time ranged from 19 hours for the Control group up to 24 hours for the animals of Sepsis + Aloe group, corresponding to a survival time of 1.26 times greater (p<0.01). There were no difference between the Sham and Aloe groups and between Control and Sepsis + Aloe groups according to the four parameters analyzed (p>0.05).
Conclusions:Aloe vera delays mortality but does not attenuate kidney injury.
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