Exercise can be an effective treatment for depression. Although the efficacy of exercise is well established, little is known concerning the biological changes associated with the antidepressant effects of exercise. A randomized, controlled trial was conducted to evaluate the effects of adding exercise to the usual treatment on the thiobarbituric acid-reactive substances (TBARS) and brain-derived neurotrophic factor (BDNF) serum levels of severely depressed inpatients. Twenty-six participants were randomized to an exercise group (n=15, exercise+treatment as usual) or a control group (n=11, treatment as usual). The participants in the exercise group completed a targeted dose of 16.5 kcal/kg/week of aerobic exercise, three times per week, throughout their hospitalizations. The control group did not exercise during their hospitalizations. The mean hospitalization length was of 21.63 (4.5)×23.82 (5.7) days for exercise and control groups, respectively. The exercise group performed a median of nine sessions. After adjusting for previous tobacco use, a significant group×time interaction was found for TBARS serum levels (p=0.02). A post hoc Bonferroni test revealed differences between the exercise and control groups at discharge. A significant time effect (p<0.001) but no group×time interaction was found (p=0.13) for BDNF serum levels. Adding exercise to the usual treatment of severely depressed inpatients decreases the TBARS serum levels of severely depressed inpatients after 3 weeks. Adding exercise had no additional effects on BDNF serum levels.
Reformulación curricular de los cursos de Terapia Ocupacional: resultados y desafíos de un recorrido (resumen: p. 16) Este artigo relata o processo de reformulação curricular do Curso de Terapia Ocupacional da Universidade Federal do Paraná ocorrido no período de 2013 a 2016. As justificativas para a reformulação foram: a necessidade de alinhamento com as atuais políticas públicas nacionais e os parâmetros nacionais e internacionais para formação profissional. O processo ocorreu de modo participativo e problematizador, culminando em uma matriz curricular delineada por eixos e ênfases específicas, com 3.305 horas distribuídas em cinco anos. A proposta pedagógica contempla a diversidade teórico-prática e didático-metodológica dos docentes. Consideraram-se também: a especificidade da formação em período noturno, o perfil dos estudantes ingressantes, a necessidade de redução nos índices de retenção e evasão, e as mudanças no mercado de trabalho. O desafio agora é a implantação gradativa e a avaliação continuada do novo currículo, de modo a garantir a formação esperada.Palavras-chave: Currículo. Terapia Ocupacional. Ensino superior.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.