Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Silva, Nairléia dos Santos; Groff, Ana Cláudia Mello; Vidor, Ana Carla Martins; Grisi-Filho, José Henrique Hildebrand; Heinemann, Marcos Bryan; Dias, Ricardo Augusto; Telles, Evelise Oliveira; Gonçalves, Vı́tor Salvador Picão; Amaku, Marcos; Ferreira, Fernando; Neto, José Soares Ferreira

doi:10.5433/1679-0359.2016v37n5supl2p3519

Cited by 20 publications

(25 citation statements)

References 22 publications

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“…The states of Santa Catarina, São Paulo, Minas Gerais, Rondônia, Mato Grosso, Mato Grosso do Sul, and Rio Grande do Sul carried out a second study on the prevalence of brucellosis. Of the 7 states included in this study a decrease in the prevalence of infected herds, as a consequence of the immunization program, was observed only in the states of Mato Grosso, Mato Grosso do Sul, Minas Gerais, and Rondônia (BARDDAL et al;BAUMGARTEN et al, 2016;DIAS et al, 2016;INLAMEA et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016;SILVA et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

Anzai

Costa²,

Said

et al. 2016

SCA

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A cross-sectional study was carried out between January 2012 and May 2014 to estimate the prevalence of bovine brucellosis in the state of Espírito Santo, Brazil. This study was carried out 11 years after the implementation of the immunization program for heifers with a vaccine derived from the S19 strain of Brucella abortus. The state was divided into two regions. Three hundred farms from each region, with reproductive activity, were randomly chosen and included as primary sample units. A fixed number of cows were randomly selected and tested for antibodies against Brucella spp. A farm was considered to be infected when at least one female tested positive for Brucella spp. In the selected farms, an epidemiological questionnaire based survey, focused on herd traits as well as husbandry and sanitary practices, was conducted, to evaluate the factors associated with the risk of infection. The overall prevalence of infected herds was 9.3% (95% confidence interval, 95% CI = 7.1-11.8%), varying from 8.7% (95% CI = 5.7-12.6%) in region 2 to 9.7% (95% CI = 6.8-13.4%) in region 1. There was no significant difference in the prevalence between the regions. The apparent prevalence of Brucella spp. positive farms across the regions and the state was similar to the prevalence observed 11 years earlier.The prevalence of positive animals was 3.8% (95% CI = 0.9-10.1%), varying from 1.5% (95% CI = 0.8-2.4%) in region 1 to 7.9% (95% CI = 1.9-20.3%) in region 2, without a significant difference between the regions. There was no difference in the number of Brucella spp. positive animals after 11 years of the immunization program. The risk factors associated with brucellosis were (i) more than 10 cows per herd (OR = 5.0; 95% CI =2.5-11.1) and (ii) equipment, feedstock, or personnel sharing (OR = 2.2; 95% CI = 1.1-4.2). The state of Espírito Santo should seek systematic vaccination coverage targeting more than 80% of the eligible heifers. An efficient animal health program, which educates the farmers to test replacement animals for brucellosis before introducing them to their herds, to avoid equipment, personnel or feedstock sharing with farms of unknown sanitary conditions, and to increase awareness of the importance of good sanitary procedures during artificial insemination, should be implemented. Anzai, E. K. et al. ResumoPara estimar a prevalência e os fatores de risco da brucelose bovina no Estado do Espírito Santo (Brasil), foi realizado um estudo transversal entre janeiro de 2012 e maio de 2014. Esse estudo foi realizado 11 anos após a implementação de um programa de imunização em novilhas utilizando uma vacina derivada da estirpe S19 de Brucella abortus. O estado foi dividido em duas regiões. Trezentas propriedades com atividade reprodutiva foram aleatoriamente selecionadas em cada região e incluídas como unidades primárias de amostragem. Um número fixo de fêmeas adultas foi aleatoriamente selecionado em cada propriedade. Os animais foram testados para anticorpos contra Brucella spp. Um questionário epidemiológico foi ...

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Section: Introductionmentioning

confidence: 99%

An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

Anzai

Costa²,

Said

et al. 2016

SCA

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“…The States of São Paulo, Minas Gerais, Espírito Santo, Rondônia, Mato Grosso, Mato Grosso do Sul, and Rio Grande do Sul have conducted a second prevalence study of brucellosis to assess the effectiveness of their vaccination programs; however, a decrease in prevalence of infected herds was only confirmed in Mato Grosso, Mato Grosso do Sul, Minas Gerais and Rondônia (BARDDAL et al;DIAS et al, 2016;ANZAI et al, 2016;INLAMEA et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016;SILVA et al, 2016). The very low prevalence found in Santa Catarina led the MAPA to prohibit vaccination with the B19 strain in the state and encouraged it to build strategies for the eradication of the disease.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors for bovine brucellosis in the State of Santa Catarina, Brazil

Baumgarten

Veloso

Grisi-Filho

et al. 2016

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A study was conducted to verify that the State of Santa Catarina has maintained a low prevalence of bovine brucellosis, which would allow the state to move forward with implementing strategies for disease eradication. The state was divided into five regions. In each region, a predetermined number of randomly selected properties was sampled. In each property, blood samples were collected from randomly selected cows with ages equal to or greater than 24 months. Sera from the animals were submitted to a serial testing protocol, with screening by the buffered acidified antigen test and confirmation by the 2-mercaptoethanol test. In each property, a questionnaire was used to identify the risk factors associated with the disease. In the state, the prevalence rate of infected herds was 0.912% [0.297 -2.11] and infected animals was 1.21% [0.09 -4.97]. Relative to the earlier study in 2002, there was no difference. The risk factors associated with the condition of a herd infected with brucellosis were as follows: herd size ≥ 12 cows (OR = 7.47 [2.14 -34.34]) and the presence of flooded areas ). In view of the low prevalence, it is recommended that the state proceed with the implementation of eradication strategies that are based on a surveillance system structured to detect and eliminate infected herds, and supported by an effective compensation fund for the replacement of seropositive animals. Additionally, the State should make a significant effort to educate and supervise producers to ensure the testing of breeding animals for brucellosis before introducing them into their properties. Key words: Brucellosis. Prevalence. Risk factors. Surveillance System. Santa Catarina. Brazil. ResumoFoi realizado um estudo para verificar se Santa Catarina continua com baixas prevalências de brucelose bovina, permitindo ao estado avançar de forma segura no seu projeto de implementação de estratégias de erradicação da doença. O estado foi divido em cinco regiões e em cada uma delas foi amostrado um número preestabelecido de propriedades, aleatoriamente selecionadas. Em cada propriedade foram colhidas amostras de sangue de fêmeas com idade igual ou superior a 24 meses, também selecionadas aleatoriamente. Os soros dos animais foram submetidos a um protocolo de testes em série, com triagem (OR = 7,47 [2,34]) e a presença de áreas alagadiças (OR = 5,68 [1,13]). Tendo em vista a baixa prevalência, recomenda-se que estado deve dar seguimento à implementação de estratégias de erradicação, baseadas na estruturação de sistema de vigilância para detecção e saneamento de focos, apoiado por eficiente fundo de indenização para a reposição de animais positivos aos testes sorológicos. Adicionalmente, o estado deveria realizar um grande esforço de educação e de fiscalização, para que os produtores testem os animais de reprodução para brucelose antes de introduzi-los em suas propriedades. Palavras-chave: Brucelose. Prevalência. Fatores de risco. Sistema de vigilância. Santa Catarina. Brasil.

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“…The States of São Paulo, Minas Gerais, Espírito Santo, Mato Grosso, Mato Grosso do Sul and Rio Grande do Sul have conducted a second study of the prevalence of brucellosis to verify the effectiveness of their vaccination programs, however, a decrease in prevalence of infected herds was only verified in Mato Grosso, Mato Grosso do Sul and Minas Gerais (BARDDAL et al, 2016;DIAS et al, 2016;ANZAI et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016;SILVA et al, 2016). The State of Santa Catarina, which had the lowest prevalence of infected herds and animals, and prohibited vaccination and initiated the implementation of eradication strategies, also conducted a second prevalence study that revealed no change (BAUMGARTEN et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Effect of vaccination in lowering bovine brucellosis in the State of Rondônia, Brazil

Inlamea

Rocha²,

Ferreira

et al. 2016

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The study was carried out to evaluate the effectiveness of the vaccination program against bovine brucellosis, implemented by the State of Rondônia, using prevalence rates as an indicator. The State was divided into three regions. For each region, a pre-determined number of herds were selected and at each herds, blood samples were collected from randomly chosen females with 24 months age or more. Sera from animals were submitted to a serial testing protocol, with screening performed using the buffered acidified antigen test and confirmation by the complement fixation test. A epidemiological questionnaire was administered to each farm property to identify the risk factors associated with the disease. The prevalence rates of infected herds and infected animal at the state were 12.3% [10.3-14.6] and was 1.9% [1.4-2.5], respectively. Between the regions, the prevalence of infected herds varied from 11.6% to 12.8% and the prevalence of infected animals ranged between 1.4% and 2.6%. Bovine brucellosis in Rondônia State is associated with the beef herd, a larger number of cows and the presence of flooded pastures. There was an important reduction in prevalence rates of infected herds and infected animals since 2004, however further reduction could still be achieved with vaccination. Thus, the State should continue its vaccination program, placing emphasis on ensuring the quality of the process. In addition, it should also promote the use of a vaccine that does not induce antibody formation. Additionally, the State must carry out a great effort of education so that producers test breeding animals for brucellosis before introducing them onto their properties and, where possible, prevent calved cows from having access to areas that are flooded. Key words: Bovine brucellosis. Vaccination. Prevalence. Risk factors. Rondônia. Brazil. ResumoO estudo foi realizado para se verificar a eficácia do programa de vacinação contra brucelose bovina implementado pelo estado de Rondônia, utilizando-se a prevalência como indicador. O Estado

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Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Cited by 20 publications

References 22 publications

An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

Prevalence and risk factors for bovine brucellosis in the State of Santa Catarina, Brazil

Effect of vaccination in lowering bovine brucellosis in the State of Rondônia, Brazil

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