An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

Anzai, Eleine Kuroki; Costa, Daniele da; Said, Alba Luisa Pereira Ribeiro; Grisi-Filho, José Henrique Hildebrand; Amaku, Marcos; Dias, Ricardo Augusto; Ferreira, Fernando; Galvis, Jason A.; Gonçalves, Vı́tor Salvador Picão; Heinemann, Marcos Bryan; Telles, Evelise Oliveira; Neto, José Soares Ferreira

doi:10.5433/1679-0359.2016v37n5supl2p3437

Cited by 23 publications

(26 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, the vaccination program developed by the state did not result in lower prevalence rates. Similar results have been reported for São Paulo and Espírito Santo ANZAI et al, 2016). Thus, it is recommended that Rio Grande do Sul continue with their vaccination program, targeting vaccination coverage around 80% , with an emphasis on the quality of the process, from marketing the vaccine to its application.…”

Section: Discussionsupporting

confidence: 68%

“…The states of São Paulo, Minas Gerais, Espirito Santo, Rondônia, Mato Grosso, and Mato Grosso do Sul conducted a second brucellosis prevalence study in order to verify the effectiveness of their immunization programs. However, only in Mato Grosso, Mato Grosso do Sul, Minas Gerais, and Rondônia was a decrease in the prevalence of infected herds confirmed (BARDDAL et al, 2016;DIAS et al, 2016;ANZAI et al, 2016;INLAMEA et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016). The state of Santa Catarina, which had the lowest prevalence of infected herds and animals, prohibited vaccinations and initiated the implementation of eradication strategies.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Silva

Groff

Vidor

et al. 2016

SCA

Self Cite

View full text Add to dashboard Cite

This study aimed to evaluate the effectiveness of a bovine brucellosis vaccination program in Rio Grande do Sul, with prevalence as the indicator, and to identify risk factors for the disease. The state was divided into seven regions. For each region, a predetermined number of properties were randomly sampled, in which a pre-established number of randomly selected females aged over 24 months were tested. The serodiagnosis protocol consisted of a screening test using buffered acidified antigen, followed by a confirmatory test using 2-mercaptoethanol. An epidemiological questionnaire was utilized to identify possible risk factors associated with bovine brucellosis. In the state of Rio Grande do Sul, the prevalence of infected herds was found to be 3.54% [2.49-4.88], and the prevalence of infected animals was 0.98% [0.57-1.57]. In assessments of specific regions, the infected herd prevalence ranged from 0.66% to 3.09%, and among the animals, from 0.06% to 2.03%. In herds comprising 15 or more cows, beef type and pasture sharing emerged as risk factors for bovine brucellosis in the state. The epidemiological status of bovine brucellosis in Rio Grande do Sul has remained unchanged since 2004, even though adequate vaccination coverage has been recorded since 2009. Thus, the state should continue its vaccination program, with emphasis on the quality of the process and on encouraging the use of nonantibody inducing vaccines. In addition, the state must make a greater effort to educate producers on the importance of testing for brucellosis in breeding animals before introducing them onto their properties, and on the importance of avoiding shared grazing among herds whose health conditions are unknown. preestabelecido de propriedades nas quais foi testado um número também preestabelecido de fêmeas com idade igual ou superior a 24 meses, aleatoriamente selecionadas. O protocolo do sorodiagnóstico foi composto de triagem com o teste do antígeno acidificado tamponado, seguido de teste confirmatório dos positivos com o teste 2-Mercaptoetanol. Nas propriedades foi aplicado um questionário epidemiológico sobre possíveis fatores de riscos associados à brucelose bovina. No estado do Rio Grande do Sul, a prevalência de focos foi de 3.54% [2.49 -4.88] e a de animais 0.98% [0.57 -1.57]. Nas regiões, as prevalências de focos variaram de 0.66% a 9.03% e a de animais de 0.06% a 2.03%. Rebanhos com 15 ou mais vacas, tipologia corte e compartilhamento de pastagens emergiram como fatores de risco para brucelose bovina no estado. A situação epidemiológica da brucelose bovina no Rio Grande do Sul manteve-se estável desde 2004, a despeito de boas coberturas vacinais terem sido registradas a partir de 2009. Assim, o estado deve continuar seu programa de vacinação, dando ênfase para a qualidade do processo e estimulando a utilização da vacina não indutora de anticorpos. Adicionalmente, o estado deve realizar um grande esforço de educação para que os produtores testem os animais de reprodução para brucelose antes de introduzi-los em sua...

show abstract

Section: Discussionsupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Silva

Groff

Vidor

et al. 2016

SCA

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, a decrease in the prevalence of infected herds was found only in Mato Grosso, Mato Grosso do Sul, Minas Gerais and Rondônia (BARDDAL et al, 2016;ANZAI et al, 2016;INLAMEA et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016;. The state of Santa Catarina, which had exhibited the lowest prevalence of infected herds and animals, had prohibited the vaccination and had, instead, implemented eradication strategies.…”

Section: Introductionmentioning

confidence: 99%

Mathematical modeling of bovine brucellosis control using the RB51 vaccine

Souza

Neto

Amaku

et al. 2016

SCA

Self Cite

View full text Add to dashboard Cite

The Brazilian Ministry of Agriculture, Livestock and Food Supply established the National Program for Control and Eradication of Brucellosis and Tuberculosis (PNCEBT) in 2001. One of the main strategies adopted by the program is the mandatory vaccination of heifers between three and eight months of age with the B19 strain. In 2007, Brazil allowed the use of RB51 vaccine in bovine females over 8 months of age as an option for the producer, but kept the B19 strain as a mandatory vaccine. This decision is based on the assumption that combining the two vaccines allows to achieve significant vaccination coverage sooner and, consequently, accelerates the fall speed of prevalence. Thus, this study aimed to measure the impact of the combined use of these two vaccines in reducing the prevalence, using as a tool the mathematical modeling. It was concluded that vaccination by RB51, if adopted as a complement to vaccination by B19, mean decrease in the prevalence of bovine brucellosis in less time. Key words: Bovine brucellosis. Thematical modeling. Vaccine. B19. RB51. ResumoO Ministério da Agricultura Pecuária e Abastecimento brasileiro instituiu o Programa Nacional de Controle e Erradicação da Brucelose e da Tuberculose Animal em 2001. Uma das principais medidas adotadas pelo programa é a vacinação obrigatória de fêmeas entre três e oito meses de idade com a cepa B19. Em 2007, o Brasil permitiu a utilização da vacina RB51 em fêmeas bovinas com mais de 8 anos de idade como uma opção para o produtor, porém manteve como vacina obrigatória a B19 em bezerras de 3 a 8 meses de idade. Essa decisão parte do princípio de que combinando as duas vacinas abrevia-se o tempo para a obtenção de coberturas vacinais expressivas na população de fêmeas em idade de procriar e, consequentemente, acelera-se a velocidade de queda da prevalência. Assim, o presente estudo objetivou medir o impacto do uso combinado dessas duas vacinas na redução da prevalência, utilizando como instrumento a modelagem matemática. Concluiu-se que a vacinação pela RB51, se adotada de forma complementar à vacinação pela B19, significaria queda da prevalência da brucelose bovina em menor intervalo de tempo. Palavras-chave: Brucelose bovina. Modelagem matemática. Vacina. B19. RB51

show abstract

“…The States of São Paulo, Minas Gerais, Espírito Santo, Mato Grosso, Mato Grosso do Sul and Rio Grande do Sul have conducted a second study of the prevalence of brucellosis to verify the effectiveness of their vaccination programs, however, a decrease in prevalence of infected herds was only verified in Mato Grosso, Mato Grosso do Sul and Minas Gerais (BARDDAL et al, 2016;DIAS et al, 2016;ANZAI et al, 2016;LEAL FILHO et al, 2016;OLIVEIRA et al, 2016;SILVA et al, 2016). The State of Santa Catarina, which had the lowest prevalence of infected herds and animals, and prohibited vaccination and initiated the implementation of eradication strategies, also conducted a second prevalence study that revealed no change (BAUMGARTEN et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Effect of vaccination in lowering bovine brucellosis in the State of Rondônia, Brazil

Inlamea

Rocha²,

Ferreira

et al. 2016

SCA

Self Cite

View full text Add to dashboard Cite

The study was carried out to evaluate the effectiveness of the vaccination program against bovine brucellosis, implemented by the State of Rondônia, using prevalence rates as an indicator. The State was divided into three regions. For each region, a pre-determined number of herds were selected and at each herds, blood samples were collected from randomly chosen females with 24 months age or more. Sera from animals were submitted to a serial testing protocol, with screening performed using the buffered acidified antigen test and confirmation by the complement fixation test. A epidemiological questionnaire was administered to each farm property to identify the risk factors associated with the disease. The prevalence rates of infected herds and infected animal at the state were 12.3% [10.3-14.6] and was 1.9% [1.4-2.5], respectively. Between the regions, the prevalence of infected herds varied from 11.6% to 12.8% and the prevalence of infected animals ranged between 1.4% and 2.6%. Bovine brucellosis in Rondônia State is associated with the beef herd, a larger number of cows and the presence of flooded pastures. There was an important reduction in prevalence rates of infected herds and infected animals since 2004, however further reduction could still be achieved with vaccination. Thus, the State should continue its vaccination program, placing emphasis on ensuring the quality of the process. In addition, it should also promote the use of a vaccine that does not induce antibody formation. Additionally, the State must carry out a great effort of education so that producers test breeding animals for brucellosis before introducing them onto their properties and, where possible, prevent calved cows from having access to areas that are flooded. Key words: Bovine brucellosis. Vaccination. Prevalence. Risk factors. Rondônia. Brazil. ResumoO estudo foi realizado para se verificar a eficácia do programa de vacinação contra brucelose bovina implementado pelo estado de Rondônia, utilizando-se a prevalência como indicador. O Estado

show abstract

An update on the epidemiologic situation of bovine brucellosis in the State of Espírito Santo, Brazil

Cited by 23 publications

References 24 publications

Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Epidemiological situation of bovine brucellosis after implementation of a vaccination program in Rio Grande do Sul State, Brazil

Mathematical modeling of bovine brucellosis control using the RB51 vaccine

Effect of vaccination in lowering bovine brucellosis in the State of Rondônia, Brazil

Contact Info

Product

Resources

About