The article presents an overview and summarizes the accumulated international and national experience, highlighting the formation and main stages of the development of the theoretical foundations and practical significance of the use of biomarkers in medico-ecological studies and evaluations in terms of influence of harmful chemical factors on the human organism. It is shown that in order to increase the effectiveness of evidentiary causal relationships of developing negative effects and modifying the mechanism of their development with the adverse effects of environmental factors, the need to expand scientific research in the field of biomarkers, their selection criteria, and justification of reference levels is becoming more urgent. In accordance with the opinion of experts from the Ad Hoc Collaborating Organizations on Biomarkers (UNEP, ILO and WHO), biomarkers of three classes were identified - exposure biomarkers, reflecting exposure, sensitivity, characterizing the degree of organism susceptibility to exposure and markers of negative effects, indicating the development of the body's response to the effects of risk factors. Based on the currently existing international approaches and taking into account national competencies, a characteristic was given and the practical significance of each class of biological markers was shown when solving problems of substantiating cause-effect relationships in the system «environment - human health» and making adequate management decisions.
Effects produced by hazardous occupational factors on workers employed in oil extraction often occur under low temperatures when workers have to perform their tasks outdoors. Our research goal was to assess a contribution made by cooling meteorological factors into health risks for workers performing their job tasks outdoors during a cold season in order to substantiate priority prevention activities. The research was performed on workers employed by a large oil extracting company who spent different amount of time outdoors during a cold season. A posteriori group risk was assessed according to the Guide as per results obtained via periodical medical examinations in 2017–2018. Working conditions were assessed basing on a report obtained via special assessment of working conditions and industrial control results. Cooling microclimate was assessed according to G 2.2.2006-05. Basing on the results of a priori group risk assessment, work places were ranked as per health disorders probability. It was shown that in-plant noise was the leading factor causing health risks. Besides, when working experience exceeded 20 years, cooling meteorological conditions also made a substantial contribution into risks occurrence. Obtained results indicate that it is necessary to develop medical and prevention activities for workers who have to spend a lot of time outdoors in areas with cold climatic conditions.
In the article, there have been presented literature data and given results of the authors’ own studies related to description of natural-climatic and anthropogenic health deterioration risk factors for population living in the Arctic. There have been singled out two main groups of risk factors specific for the Arctic regions.
Purpose: to study the socioeconomic and behavioral risk factors of disabilities among indigenous population of Far North and make proposals for their prevention. Methods: The study tested the level of income, employment, education and alcohol consumption on the basis of the survey and analyzed the data of the official statistics. We used Statistica v.12 and IBM SPSS Statistics v.22 for calculating the chi-square, Wilcoxon signed- rank test criteria, T-test for paired samples and made regression and correlation analysis. Results: We did not discover significant differences in income levels, unemployment and alcohol consumption in the cohort study (2001-2010) of indigenous population in Chukotka Autonomous Region. In addition, the income of the natives is still low, unemployment and alcohol consumption are high. There is a correlation between the socioeconomic and behavioral factors and health indicators. We also propose a mathematical model which allows to suggest that the level of income above the subsistence level in 6-7 times is sufficient to minimize the impact of socioeconomic factors on population health. Conclusion: In order to prevent irreversible process of indigenous population health deterioration and society degradation it is necessary to create the accessible vocational education, increase employment and number of leisure centers. These measures will lead to income growth, increase in life expectancy and infant mortality decrease.
According to a systematic review of published data in both the national and international scientific indexing systems, including the results of our own researches, there have been selected evidence-based criteria and internal genotype-phenotype risk determinants for assessing the individual susceptibility to the acute cold exposure. In accordance with these criteria, the list of cold-related health conditions was defined. This list includes 33 classes and groups of diseases and conditions by ICD-10 codes, arising from or tightly associated with the cold exposure. According to the comorbidity principles, the novel quantitative predictive model for assessing the individual susceptibility to the acute cold exposure was developed and validated. This assessment takes into account, in addition to the meteorological risk factors, also internal risk determinants, including physical status, behavioral, pathogenic and functional disorders, as well as receiving thermoregulation-altering pharmaceuticals prescribed by recommended therapeutic doses. The algorithm for calculating the individual health risk and recommended time limits based on the use of suggested comorbidity index for the acute exposure to cold in an open area or in unheated premises without special active thermal protection is described.
The aim of the study was to assess the factors affecting total mortality of the population of the Republic of Bashkortostan (RB). Methods. The study was conducted using the method of regression analysis according to panel data. The official statistical materials of the Territorial Body of the Federal State Statistics Service for the Republic of Bashkortostan (Table C 51; databases on demography and statistical yearbooks "Social and Economic Situation of Municipal Districts and Urban Districts of the Republic"; annual statistical reports in the form of "2TP - Air "); Rosstat were used as sources of secondary data. Data from 54 municipalities and 21 cities of the Republic of Bashkortostan from 2002 to 2017 were used. Altogether, 17 indicators were used for data analysis. Results. On the basis of regression analysis of panel data, risk factors for total mortality were identified: primary adult disability, number of pensioners, unemployment, crimes. It is noted that a decrease in the mortality rate is affected by an improvement in the quality of medical services, an increase in the number of enterprises, and population density. The effect of these factors varies for men and women. Conclusion. The results of the assessment allow us to identify areas of activity to reduce mortality, as well as to determine the priorities of socioeconomic policy on the regional level.
Introduction. The relevance of the study is determined by the tasks set in the National project “Demography” (Federal project “Older generation”), and is the need to take into account the functional and psycho-physiological characteristics of older age groups in the system of measures to preserve their health and efficiency in connection with the upcoming increase in the age, giving the right to retire for the majority of the working population.The aim of study was to determine the main patterns in the changes in indicators characterizing the quality of life (QL) and postural balance in women of older age groups who continue to work in their profession.Materials and methods. 166 working women aged 55–64 years (mean age 59±2.8 years) were examined. The sample included women who agreed to participate in the study and who, 12 months after the survey, continued to work and did not plan to stop working during the following year. The first age group (AG) consisted of women whose calendar age (CA) was within 55–59 years (n=89), the second — women aged 60–64 years (n=77). The physical (PCS) and psychological (MCS) components of health-related QOL were determined by the SF–36v2 questionnaire. To evaluate the components of postural balance (CPB), a sensory Organization Test (SOT) was conducted using a computer posturographic (stabilometric) complex “Smart Equitest Balance Manager”.Results. It was found that all medians of QL components in the examined women were above 50 points, i.e. exceeded the general population norm. Comparison of PCS values in AG 55–59 years and 60–64 years showed differences at the level of statistical trend (0.05>p≤0.1). When comparing MCS, no statistically significant differences between the groups were found. The study of the SOT PBC revealed that women aged 60–64 had a slight decrease in the quality of the equilibrium function in functional samples 1 (p=0.008) and 2 (p=0.009), but the quality of the equilibrium function in sample 6 (p=0.005) was higher than in women aged 55–59, which makes it possible to consider this indicator as a predictor that has a positive eff ecton the continuation of employment over 59 years.Conclusions. Thus, the physical and psychological components of QL in working women 55–64 years exceed the general population norm. However, after 59 years there is a decrease in the physical component of QL and there is no decrease in the psychological component of QL, which suggests that the psychological health of women 60 years and older becomes crucial in predicting retirement. After 59 years, working women experience a decrease in the quality of the equilibrium function in functional samples 1 and 2, indicating the beginning of age-related changes in the PBC, which justifies the need to develop and implement physical education and health programs aimed at maintaining the postural balance in 60-year-old women.
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