T. Yakaiah scite author profile

Fused pyrimidine derivatives R 0515Synthesis Leading to Novel 2,4,6-Trisubstituted Quinazoline Derivatives, Their Antibacterial and Cytotoxic Activity Against THP-1, HL-60 and A375 Cell Lines.-Twelve 2,4,6-Trisubstituted quinazoline derivatives of type (V) are prepared and screened for their antibacterial and cytotoxic effects against the title cell lines. Derivative (Vd) exhibits the highest activity against THP-1 and HL-60 cell lines, whereas (Va) and (Vb) show moderate activity. -(CHANDRIKA, P. M.; YAKAIAH, T.; NARSAIAH*, B.; SRIDHAR, V.; VENUGOPAL, G.; RAO, J. V.; KUMAR, K. P.; MURTHY, U. S. N.; RAO, A. R. R.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 48 (2009) 6, 840-847; Fluoroorg. Div., Indian Inst. Chem. Technol., Hyderabad 500 007, India; Eng.) -M. Bohle 43-171

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Synthesis and structure–activity relationships of novel pyrimido[1,2-b]indazoles as potential anticancer agents against A-549 cell lines

Yakaiah

Lingaiah

Narsaiah

et al. 2007

Bioorganic & Medicinal Chemistry Letters

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Click chemistry: Studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation – Theoretical and experimental validation

Chandrika

Yakaiah

Gayatri

et al. 2010

European Journal of Medicinal Chemistry

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Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines – Their potential as adenosine receptor ligands

Sirisha

Narsaiah

Yakaiah

et al. 2010

European Journal of Medicinal Chemistry

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Regioselective addition of Grignard reagents to 2,6-dicyanoanilines and cyclization to new quinazoline derivatives under thermal/microwave irradiation conditions

Maitraie

Yakaiah

Srinivas

et al. 2006

Journal of Fluorine Chemistry

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GdCl3 catalysed Grieco condensation: A facile approach for the synthesis of novel pyrimidine and annulated pyrimidine fused indazole derivatives in single pot under mild conditions and their anti-microbial activity

Yakaiah

Lingaiah

Narsaiah

et al. 2008

European Journal of Medicinal Chemistry

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ZnBr₂‐Catalyzed Efficient Oxidative Homo Coupling of Aryl Magnesium Bromides

Kanth¹,

Reddy²,

Yakaiah³

et al. 2006

Synthetic Communications

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T. Yakaiah

Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines☆

ChemInform Abstract: Synthesis Leading to Novel 2,4,6‐Trisubstituted Quinazoline Derivatives, Their Antibacterial and Cytotoxic Activity Against THP‐1, HL‐60 and A375 Cell Lines.

Synthesis and structure–activity relationships of novel pyrimido[1,2-b]indazoles as potential anticancer agents against A-549 cell lines

Click chemistry: Studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation – Theoretical and experimental validation

Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines – Their potential as adenosine receptor ligands

Regioselective addition of Grignard reagents to 2,6-dicyanoanilines and cyclization to new quinazoline derivatives under thermal/microwave irradiation conditions

GdCl3 catalysed Grieco condensation: A facile approach for the synthesis of novel pyrimidine and annulated pyrimidine fused indazole derivatives in single pot under mild conditions and their anti-microbial activity

ZnBr₂‐Catalyzed Efficient Oxidative Homo Coupling of Aryl Magnesium Bromides

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T. Yakaiah

Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines☆

ChemInform Abstract: Synthesis Leading to Novel 2,4,6‐Trisubstituted Quinazoline Derivatives, Their Antibacterial and Cytotoxic Activity Against THP‐1, HL‐60 and A375 Cell Lines.

Synthesis and structure–activity relationships of novel pyrimido[1,2-b]indazoles as potential anticancer agents against A-549 cell lines

Click chemistry: Studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation – Theoretical and experimental validation

Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines – Their potential as adenosine receptor ligands

Regioselective addition of Grignard reagents to 2,6-dicyanoanilines and cyclization to new quinazoline derivatives under thermal/microwave irradiation conditions

GdCl3 catalysed Grieco condensation: A facile approach for the synthesis of novel pyrimidine and annulated pyrimidine fused indazole derivatives in single pot under mild conditions and their anti-microbial activity

ZnBr2‐Catalyzed Efficient Oxidative Homo Coupling of Aryl Magnesium Bromides

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ZnBr₂‐Catalyzed Efficient Oxidative Homo Coupling of Aryl Magnesium Bromides