Cosmetics and detergents may facilitate contact sensitization because of a (too) high MI concentration, and mislabelling may make its avoidance extremely difficult. Safer use concentrations and correct labelling should be ensured by adequate quality control.

A 61-year-old woman with a history of asymptomatic oral lichen planus, proven by mucosal biopsy 15 years previously, was referred to us with oral complaints that had occurred in September 2013, shortly after the placement of a new upper dental prosthesis (consisting of a metal frame made of a Vitallium ® alloy, containing cobalt, chromium, and molybdenum, and acrylate tooth material made of polymerized methyl methacrylate (PMMA); Fig. 1). The prosthesis was used by the patient without any fixative. After a few weeks, the wearing of the prosthesis had resulted in intraoral swelling, vesicles, and small, painful, aphthous ulcers, accompanied by a metallic taste and a dry mouth. Whenever she removed the prosthesis, the complaints settled after several hours, only to recur

A combination of NES, FCT and FTT shows promising results as a clinical tool in daily practice to differentiate schizophrenia from other psychotic disorders. Future prospective studies to confirm these results are necessary.

No abstract

Voedselallergie is een veel voorkomend probleem, zowel bij huisdieren als bij de mens. Zo wordt in de diergeneeskunde vaak voedselallergie vastgesteld bij de hond. Verschillende allergenen, zoals vlees, eieren en melk, worden aangeduid als boosdoener bij de hond en soms wordt er kruisreactiviteit gezien tussen verschillende allergenen. Bij de mens zijn vooral pinda’s, noten en koemelk bekend als veelvoorkomende antigenen. De symptomen variëren zowel bij de hond als bij de mens van huidklachten tot gastro-intestinale symptomen. De diagnosestelling van voedselallergie bij de hond gebeurt het beste door middel van een testdieet, bestaande uit twee fasen: de eliminatie- en provocatiefase. Andere testen, zoals de intradermale huidtest, serologie, de basofieldegranulatietest en gastroscopische voedselovergevoeligheidstest zijn ook beschikbaar. Echter, deze testen geven vaak weinig betrouwbare resultaten. De behandeling van voedselallergie berust in de eerste plaats op de eliminatie van het allergeen in de voeding. Dit kan eventueel worden aangevuld met medicatie, zoals corticosteroïden en antihistaminica.

We provide a new method to source fatty alcohols from poly(ethylene) (PE) pyrolysis oil. To this end, we have developed a new one-pot process to obtain fatty alcohols from a mixture of long chain alkenes and alkanes (C10–C20) that is obtained from pyrolyzed PE. Hydroboration–oxidation methods with and without an isomerization step were investigated for converting all types of alkenes present in the PE pyrolysis oil to primary alcohols only, following the anti-Markovnikov rule. Our process showed 91%–98% conversion of the alkenes to alcohols in a one-pot reaction at a scale of 50 g at low temperature (10–25 °C) under ambient pressure. In addition, the efficiency of the process was confirmed by testing several types of pyrolysis oil derived from commercial waste PE where alcohol recovery reached 83%–92% based on the amount of alkenes in the PE pyrolysis oil. As fatty alcohols are commodity chemicals, our study can pave the way for converting waste plastics into high value chemicals, a welcome energy and materials saving shortcut to the specialty chemicals market.