Non-occupational sensitization to OIT from leather may occur. Patch test concentrations of >250 ppm pet. may be necessary for diagnosis, and to show cross-reactivity with MI. Safer use limits for OIT in the leather industry may be needed.

Cosmetics and detergents may facilitate contact sensitization because of a (too) high MI concentration, and mislabelling may make its avoidance extremely difficult. Safer use concentrations and correct labelling should be ensured by adequate quality control.

No abstract

A 61-year-old woman with a history of asymptomatic oral lichen planus, proven by mucosal biopsy 15 years previously, was referred to us with oral complaints that had occurred in September 2013, shortly after the placement of a new upper dental prosthesis (consisting of a metal frame made of a Vitallium ® alloy, containing cobalt, chromium, and molybdenum, and acrylate tooth material made of polymerized methyl methacrylate (PMMA); Fig. 1). The prosthesis was used by the patient without any fixative. After a few weeks, the wearing of the prosthesis had resulted in intraoral swelling, vesicles, and small, painful, aphthous ulcers, accompanied by a metallic taste and a dry mouth. Whenever she removed the prosthesis, the complaints settled after several hours, only to recur

Based on the obtained results, it can be concluded that the newly developed method is suitable for its purpose, namely the determination of ellagic acid in the crude extract of P. amarus.

Rate‐adaptive single chamber pacemakers with accelerometer, closed loop stimulation (CLS), and remote monitoring functionality (Eluna 8 SR‐T, Biotronik, SE & Co, Germany) were implanted in 3 miniature donkeys with third‐degree atrioventricular block and syncope. After recovery, different pacemaker programming modes were tested at rest, during stress without physical exercise and during physical exercise. Pacing rates were compared to actual atrial rates and showed that CLS functionality allowed physiological heart rate adaptation. A transmitter installed in the stable provided wireless connection of the pacemaker to the internet. Home monitoring was activated which performed daily wireless transmission of pacemaker functional measurements to an online server allowing diagnosis of pathological arrhythmias and pacemaker malfunction from a distance. Closed loop stimulation and remote monitoring functionality resulted in nearly physiological rate adaptation and allowed remote “from‐the‐stable” patient follow‐up.