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SARS-CoV-2 is a causative agent of Coronavirus disease-19 (COVID-19), which is considered as a fatal disease for public health apprehension worldwide. This pathogenic virus can present everywhere. As it is a virus it can extend easily and cause severe illness to humans. Hence, an efficient international attentiveness of plan is necessary to cure and prevent. In this review, epidemic outbreak, clinical findings, prevention recommendations of COVID-19 and suggestive medicinal value of south Indian plant sources have been discussed. Though the varieties of improved approaches have been taken in scientific and medicinal concern, we have to pay attention to the medicinal value of the plant-based sources to prevent these types of pandemic diseases. This is one of the suggestive and effective ways to control the spreading of viruses. In the future, it is required to provide medicinal plant-based clinical products (Masks, sanitizers, soap, etc.,) with better techniques by clinicians to contend the scarcity and expose towards the nature-based medicine rather than chemical drugs. This may be a benchmark for the economical clinical trials of specific plant material to treat the viral diseases in the future.

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A field experiment to study the “Comparative efficiency of organics and biofertilizers on growth and yield of maize (Zea mays L.)” was conducted during Kharif 2011 at farmer field in Beluguli village, Chikkanayakanahalli taluk (Tumkur district). The maize cultivar Nithyashree (NAH 2049) was used in the study. The field experiment was laid out in Randomized Complete Block Design with fourteen treatments and three replications. Results of the treatment (T13) having recommended dose of NPK + Azotobacter chroococcum + Bacillus megaterium + Pseudomonas fluorescence + enriched compost has showed highest plant height at 30, 60, 90 days after sowing and at harvest (120 days) (31.70, 180.93, 186.07 and 188.13 cm respectively). The highest total dry matter production at harvest (375.80 g) and yield parameters like Weight of cob (207.63 g), Grain yield per plant (158.93 g), Grain yield per ha (54.53 q) and Test weight of seeds (33.10 g) was also found highest in this treatment and available nutrient content in soil after crop harvest i.e., nitrogen (185.40 Kg ha-1), phosphorous (38.83 Kg ha-1) and potassium (181.47 Kg ha-1) was also found highest in the same treatment combination.

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Microbial polysaccharides produced by marine species play a key role in food and cosmetic industry, as they are nontoxic and biodegradable polymers. This investigation reports the isolation of exopolysaccharide from Bacillus licheniformis Dahb1 and its biomedical applications. Bacillus licheniformis Dahb1 exopolysaccharide (Bl-EPS) was extracted using the ethanol precipitation method and structurally characterized. FTIR and H-NMR pointed out the presence of various functional groups and primary aromatic compounds, respectively. Bl-EPS exhibited strong antioxidant potential confirmed via DPPH radical, reducing power and superoxide anion scavenging assays. Microscopic analysis revealed that the antibiofilm activity of Bl-EPS (75 μg/ml) was higher against Gram-negative (Pseudomonas aeruginosa and Proteus vulgaris) bacteria over Gram-positive species (Bacillus subtilis and Bacillus pumilus). Bl-EPS led to biofilm inhibition against Candida albicans when tested at 75 μg/ml. The hemolytic assay showed low cytotoxicity of Bl-EPS at 5 mg/ml. Besides, Bl-EPS achieved LC values < 80 μg/ml against larvae of mosquito vectors Anopheles stephensi and Aedes aegypti. Overall, our findings pointed out the multipurpose bioactivity of Bl-EPS, which deserves further consideration for pharmaceutical, environmental and entomological applications.

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