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Introduction: Saurauia plant has been widely used to treat a variety of diseases suffered by villagers at various places in the world. These species are widely used traditionally by the community as antidiabetic and digestive problems' remedy. This paper will present various uses and researches ever carried out by researchers in the world on various types of the genus Saurauia. Methods: The Information was collected from scientific journals, books, and reports. Results: This review summarizes the existing information on several species of Saurauia in relation to their chemical compounds and biological activity. There are some of chemical compounds present and identified in Saurauia, i.e. 3β-hydroxy-Olean-12-en-28oic acid; 3,19-Dihydroxyurs-12-en-28-oic acid; 3-hidroksi, 12(13)-en, 28-oleanolat acid; actinidin; several monoterpene lactones; seven triterpenoids, namely, cis-3-O-p-hydroxycinnamoyl ursolic acid; trans-3-O-p-hydroxycinnamoyl ursolic acid; ursolic acid; oleanolic acid; corosolic acid; maslinic acid; and β-amyrin; and two steroids, stigmasterol; and β-sitosterol. There are several biological activities afforded by Saurauia i.e. antioxidant activity, anti-cholesterol, antidiabetic activity, antihyperlipidemic, analgetic activity, antimicrobial activity, wound-healing activity and immunostimulatory activity.

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The bioactively rich soursop leaf extract can be encapsulated inside several natural coating materials. The extract of soursop leaf has been found to contain many bioactive compounds such as various phenolic compounds that are beneficial for anticancer, antidiabetic and many other health benefits. However due to the sensitive nature of the bioactive molecules, encapsulation procedure was applied to prolong the activity of the biomolecules. Capsule materials used in this experiment were obtained from natural extract of Okra mucilage, Aloe vera mucilage and Maltodextrin-WPI mixture to protect the unstable bioactive compounds. Homogenation time using ultrasonication and Core to Coating ratio was differed to observe the optimum encapsulation process. The encapsulation efficiency, release factor ability, size distribution and its correlation with bioactive stability are observed using Total Phenolic methods and Antioxidant Activity before and after encapsulation. Aloe vera gave best encapsulation efficiency (88-91%) while microcapsule made with Okra gave the best antioxidant activity (DPPH IC50 633-710ppm), and maltodextrin-WPI gave best powder recovery (yield 70-73%). Keywords: aloe mucilage, antioxidant activity,  encapsulation, okra mucilage, soursop tea extract

Resveratrol derivatives have been reported to have important bioactivities. Synthesis of monomeric resveratrol derivatives has been a challenging topic in both organic and medicinal chemistry. A Synthesis of prenylated resveratrol was developed through prenylation between resveratrol (3,5,4'-trihydroxystilbene) and prenyl bromide (3,3-dimethyl allyl bromide) using heterogeneous superbase catalyst γ-Al2O3/NaOH/Na. The aim of this research is to obtain prenylated resveratrol compound that has important bioactivity and to identify a type of prenylation, O-or C-prenylation. Characterization of the product was carried out using liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance ( 1 H-NMR). The antioxidant activity of the samples was determined using DPPH radical scavenging assay. The results of LC-MS analysis of the product showed the molecular ion peak at m/z 365.38 [M+H] + that indicated the presence of prenylated resveratrol with two prenyl (C5H9-) substituent. The 1 H-NMR spectrum of the product indicated that the addition of two prenyl substituent occurs at the hydroxyl group on the structure of resveratrol (O-prenylation). Prenylation caused decreasing free radical scavenging activity of the product (IC50 = 102,75 ppm) compared to resveratrol (IC50 = 63,52 ppm) and it means that the addition of prenyl substituents occurs through O-prenylation.

A heterogeneous base catalyst, Na-CaO, was prepared by wet impregnation of NaOH solution on CaO solid support originated from chicken eggshells waste. Material characterization using TGA, FTIR, XRD, SEM, EDAX and BET surface area has confirmed the formation of Na-CaO. The catalyst was applied in chalcone syntheses between acetophenone and vanillin at several reaction conditions, such as various weight of catalyst, temperature, type of solvents and reaction time. The highest yield of product (97%) was obtained from the reaction in ethanol, with 0.3 g of catalyst at 60 o C for 1 hour. This research provides a new route of chalcone syntheses by green environmentally catalyst support of chicken eggshells waste.

Guttiferron F and essential oil were isolated from extract n-hexane of Garcinia cf bancana Miq. Antioxidant activity was done by DPPH method to  n-hexane, methanol, ethyl acetate, n-butanol extracts and Guttiferron F, showed activity with IC50  24.5, 22.4, 29.2, 37.6 and 25.8 µg/mL respectively. The structure elucidation of Guttiferon F  based on spectroscopy data of IR, NMR of 1H and 13C.Keywords: Antioxidant, Garcinia  cf bancana Miq., Essential oil and  Guttiferon-F.

Antioksidan adalah suatu senyawa yang dapat menangkap radikal bebas. Salah satu sumber anti oksidan alami adalah dari tumbuh-tumbuhan. Dalam usaha pencarian antioksidan baru, telah dilakukan identifikasi senyawa antioksidan dari ekstrak n-heksana kulit batang Garcinia bancana Miq dengan metode 1,1-difenil-2-pikrilhidrazil (DPPH). Metode isolasi dilakukan dengan cara  kombinasi kromatografi (Kromatografi kolom vacum, kromatografi kolom gravitasi, kromatografi lapis tipis  sentrifugal dan kromatografi lempeng tipis)  Penentuan struktur molekul berdasarkan analisis data spektroskopi UV-VIS, IR, LC-MS, NMR proton dan karbon. Dari  hasil isolasi didapatkan suatu senyawa isoprenil bezofenon dengan bobot molekul 466,22 dan  rumus molekul C28H34O6 dengan nama IUPAC 3-(3,4-dihidroksibenzoil)-4-hidroksi-8-8-dimetil-1,7-bis(3-metilbut-2enil) bisiklo (3.3.1) non-3-ene-2,9-dione atau disebut bacanone yang diduga senyawa baru. Dari proses isolasi juga ditemukan senyawa atsiri b- caryophyllene, α-humulene dan b-cadinene serta stigmasterol. Hasil uji aktivitas antioksidan ekstrak n-heksana dan hasil isolat murni menunjukkan IC50 berturut-turut 17,78 ppm dan 12,79 ppm dimana pembanding kuersetin adalah 9,90 ppm.Kata kunci:  Garcinia bancana, antioksidan, DPPH, 3-(3,4-dihidroksibenzoil)-4-hidroksi-8-8-dimetil-1,7-bis(3-metilbut-2enil)bisiklo(3.3.1)no-3-ene-2,9-dione, bacanone. Antioxidants are compounds that can capture free radicals. One source of natural antioxidant is from plants. On searching  for new antioxidant, identification of antioxidant compound of the n-hexane extract of the stem bark of Garciniabancana Miq was done by  1.1-diphenyl-2-pikrilhidrazil (DPPH) method. Isolation active compound were done by combination of chromatographic methods (Flash column chromatography, gravitation column chromatography, cetrifugal thin layer chromatography and thin layer chromatography) .Determination of molecular structure by analysis spectroscopic data of UV-VIS, IR, LC-MS, NMR proton and carbon.Isolation results were      isophrenyl bezophenon with molecular weight 466.22 and the molecular formula is C28H34O6 IUPAC name 3 - (3,4-dihydroxybenzoil)-4-hydroxy-8-8-dimethyl-1,7-bis (3-methylbut-2enyl) bicyclo (3.3.1) non-3-ene-2,9-dione or named bacanone wich is suspected as a new compound. From the isolation were also found of known volatile compounds b - caryophyllene, α-humulene and b-cadinene and stigmasterol. The test results of antioxidant activity of  n-hexane extract and pure compound  showed IC50 respectively 17.78 ppm and 12.79 ppm which comparison with  quercetin is 9.90 ppm. Key words :  Garcinia bancana Miq., antioxidant, DPPH, 3-(3,4-dihydroxybenzoil)-4-hidroxy-8-8-dimethyl-1,7-bis (3-methylbut-2enil)bisiklo(3.3.1)no-3-ene-2,9-dione, bacanone.