COVID-19 adalah penyakit menular disebabkan SARS-CoV-2 yang telah menyebar menjadi pandemi di seluruh dunia termasuk Indonesia. COVID-19 dapat berupa penyakit ringan atau sampai kematian dan obat untuk COVID-19 belum ada. Indonesia merupakan negara yang kaya akan tanaman herbal, yang sudah banyak digunakan di masyarakat. Dua tanaman herbal yang sering digunakan adalah jahe dan serai. Berdasarkan penelitian tanaman ini dapat memelihara kesehatan dan meningkatkan sistem imun. Tujuan pengabdian masyarakat ini adalah untuk memberikan pengetahuan tentang manfaat jahe serai dan keterampilan membuat wedang jahe serai dalam rangka peningkatan sistem imun pada masa pandemi COVID-19. Metode yang digunakan adalah penyuluhan dan demonstrasi pembuatan wedang jahe serai serta mengikutsertakan responden untuk berpartisipasi aktif dalam pembuatan wedang jahe serai. Pada pengabdian masyarakat ini didapatkan hasil adanya peningkatan pengetahuan responden mengenai manfaat wedang jahe serai dan cara pembuatannya. Diharapkan setelah pengabdian masyarakat ini responden dapat menerapkan dan mengaplikaskan pengetahuan yang didapatkan dalam rangka meningkatkan sistem imun pada masa pandemi COVID-19
This study aims to prove that the administration of red dragon fruit extract (Hylocereus polyrhizus) has an effect on membrane lipid peroxidation and liver tissue damage triggered by hyperlipidemia in white rats (Rattus norvegicus). This study used trueexperimental design with using 30 male Wistar rats which were divided into 5 groups. Group K1-K4 was given treatment for 8 weeks and group K5 for 16 weeks. The group consists of K1 negative control (standard diet); K2 positive control (standard diet and quail eggs 10 ml / kgBW); K3 (standard diet, quail eggs 10 ml / kgBW and simvastatin 0.72 mg / day); K4 (standard diet, quail eggs 10 ml / kgBW and red dragon fruit extract dose 60 mg / day) for 8 weeks and K5 (standard diet, quail eggs 10 ml / kgBW and red dragon fruit extract dose 60 mg / day) for 16 weeks. Data was analyzed by One Way ANOVA test, followed by the Wilcoxon Man-Whitney Post Hoc test (P-value <0.05) in 8 weeks treatment. K3 and K4 groups showed improvement in MDA concentration and improvement of liver tissue (P-value <0.05) compared to K2. Red dragon fruit extract 60 mg/day has a potential effect in repairing lipid peroxidation damage on liver cell membrane in hyperlipidemia conditions with high fat diet.
Tobacco plants are one of the main trade commodities in Indonesia. At present, the main production of tobacco is cigarettes. However, tobacco has active antibacterial compounds, such as phenols, alkaloids, and essential oils. Therefore, tobacco can be used in the health sector. This study was conducted to determine the effectiveness of the pyrolysis extract of Nicotiana tabacum L. var Virginia in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. This study uses a true experimental research design with tobacco extract samples obtained by pyrolysis at concentrations of 20%, 40%, 60%, 80%, and 100%. The antibacterial test carried out was the Kirby-Bauer diffusion method on Mueller Hinton Agar (MHA) media. One-Way ANOVA test results with p < 0.05 indicate the effectiveness of tobacco pyrolysis extract in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. The average yield of inhibition zones found in Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa were 6.35 mm, 5.9 mm, 3.97 mm, and 5.025 mm. From these results, Staphylococcus aureus bacteria became the most sensitive bacteria with Virginia tobacco pyrolysis extract.
ABSTRAKKasus Demam Berdarah Dengue (DBD) di Desa Pabean Udik Kabupaten Indramayu masih tinggi. Penyakit Demam Berdarah Dengue (DBD) merupakan penyakit menular yang masih banyak menimbulkan kesakitan dan kematian. Sampai saat ini belum ada pengobatan penyebab, hanya pengobatan simptomatis dan suportif. Tujuan kegiatan adalah untuk meningkatkan tingkat pengetahuan tentang DBD dan tanaman obat pada masyarakat pesisir desa Pabean Udik Indramayu sebagai upaya pengendalian dan pencegahan DBD. Metode kegiatan berupa penyuluhan tentang DBD dan tanaman TOGA, pelatihan pemantauan jentik (JUMANTIK), dan pemberian beberapa jenis TOGA untuk ditanam di lingkungan rumah. Sebelum kegiatan dilakukan pretes dan setelah penyuluhan dilakukan posttest untuk mengetahui keberhasilan kegiatan. Lokasi penelitian di Desa Pabean Udik Kabupaten Indramayu pada bulan Oktober 2022 dengan peserta berjumlah 30 orang dan menggunakan media penyuluhan PowerPoint. Hasil pengabdian didapatkan bahwa karakteristik peserta sebagian besar responden berusia 36-45 tahun (33,3%), berpendidikan SD (40,7%). Terdapat peningkatan tingkat pengetahuan 10,19 (16.79 %), dimana nilai rata-rata setelah promosi kesehatan 70,89 sedangkan nilai rata-rata sebelum kesehatan promosi 60,70. Pelatihan ini akan dapat membantu tercapainya lingkungan yang sehat sehingga nyamuk tidak berkembang biak dan kejadian demam berdarah akan dapat berkurang. Kata kunci: DBD; pengetahuan; promosi kesehatan ABSTRACTDengue Hemorrhagic Fever (DHF) is an infectious disease that still causes a lot of morbidity and mortality. Until now, there has been no causative treatment, only symptomatic and supportive treatment. According to a report from the Indramayu District Health Office, DHF cases in Pabean Udik Village are still high. The purpose of this study was to determine the level of knowledge before and after health promotion. This study used an observational analytic design with a cross-sectional approach. The research location was in Pabean Udik Village, Indramayu Regency, in October 2022. Respondents were residents of Pabean Udik Village, Indramayu Regency, totaling 30 people. The dependent variable is the level of knowledge. The independent variable is health promotion using PowerPoint. Data collection using a questionnaire. Most of the respondents were aged 36-45 years (33.3%), had primary school education (40.7%), The average value after health promotion was (Mean = 70.89; SD = 1.805; p = 0.000) while the average value before health promotion (Mean = 60.70; SD = 1.708 ; p = 0.000) answers to questions that increased sharply about first aid if were felt by DHF syndrome. Health promotion increases the level of knowledge of the residents of Pabean Udik Village, Indramayu Regency Keywords: DHF; knowledge; health promotion
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