diagnostic value of US significantly exceeds the clinical examination when scrotal edema has developed. Conclusions. In summary, the Doppler US is a highly sensitive preoperative diagnostic tool for scrotal pain. The sensitivity and specificity of physical examination signs of the acute scrotum in the absence of scrotal edema in children are higher than the US findings, but significantly drops after the onset of scrotal edema. 8. Schalamon J., Ainoedhofer H., Schleef .J et al. Management of acute scrotum in children the impact of Doppler ultrasound.

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S mallheart anomalies are a heterogeneous group of cardiovascular system development disorder in the form of anatomical abnormalities of heart structure and great vessels which occurred in embryoor ontogenesis [8,10]. Small heart anomalies are usually being interpreted as pathology only in cases of overt forms (arrhythmias, clinically significant valvular regurgitation, etc) and rarely being considered from these positions in relation to young people -even on a stage of occupational guidance or military medical examination. Meanwhile, small heart anomalies are one of the pathologies which caused high-frequency of rhythm disorder (from 50 % up to 90 %) including young age and development of sudden arrhythmic death [11]. This is precisely why timely detection is important in population of small heart anomalies of patients with high risk of cardiovascular complications, first of all, arrhythmia.One of the risk factor of dangerous arrhythmia and sudden cardiac death is long/short QT interval [5,12]. In case of hereditary QT prolongation one can observe specific gene mutations, disorder of genetic control of ion channel proteins with electrophysiological consequences. Data comparison of genetic research with associated phenotypic manifestations of different molecular genetic variations of long and short QT syndrome made it possible to refine their diagnostics on the stage proceeding to genotyping. In recent years there is an active search for new mutations takes place and diagnostics of so called «silent» pathology forms which are being manifested under certain conditions is still actual [9]. In addition to this, there is lack of information in literature about frequency and clinical significance of changes

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Yagoda a. V., gladkikh n. n. stavropol state Medical University, russia Выявлена взаимосвязь плазменных E-, L-, P-селектинов, молекулы межклеточной адгезии 1 типа (ICAM-1), тромбоцитарно-эндотелиальной адгезивной молекулы 1 типа (РЕСАМ-1) и сосудистой молекулы адгезии 1 типа (VCAM-1) с различными типами геометрии левого желудочка при пролапсе митрального клапана (ПМК). Обследовано 89 пациентов (68 мужчин и 21 женщина, средний возраст 22,1±4,4 лет) с ПМК. Контрольную группу составили 10 здоровых людей, сопоставимых по полу и возрасту. У 79,8 % пациентов с ПМК отмечена нормальная геометрия левого желудочка, у 19,1 %-эксцентрическая гипертрофия и у 1,1 %-концентрическая гипертрофия. В случаях ПМК с эксцентрической гипертрофией левого желудочка уровень ICAM-1 был максимальным. Показатели Е-селектина и VCAM-1 характеризовались высокими значениями независимо от типа геометрической модели левого желудочка. Уровни L-, Р-селектинов и РЕСАМ-1 не имели достоверных различий с контролем. Таким образом, эксцентрическая гипертрофия миокарда левого желудочка у пациентов с ПМК ассоциирована с гиперпродукцией ICAM-1. Ключевые слова: пролапс митрального клапана, молекулы адгезии, ремоделирование миокарда To determine the relation of plasma E-, L-, P-selectines, type 1intercellular adhesion molecule (ICAM-1), type 1 platelet-endothelial cell adhesion molecule (PECAM-1) and type 1vascular cell adhesion molecule (VCAM-1) with different types of the left ventricular geometry in patients with mitral valve prolapse (MVP). 89 patients (68 male and 21 women, aged 22.1±4.4 years) with MVP were examined. The control group consisted of 10 age-and sex-matched healthy subjects. The normal geometry of the left ventricle was found in 79.8 % of patients with MVP, eccentric and concentric hypertrophy were found in 19.1 % and 1.1 % of cases, respectively. The maximum level of ICAM-1 was observed in patients with MVP and eccentric hypertrophy of the left ventricle. The concentrations of E-selectin and Сведения об авторах:

epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages.

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Ставропольский государственный медицинский университет 2 Ставропольская краевая клиническая больница МЕДИЦИНСКИЙ ВЕСТНИК СЕВЕРНОГО КАВКАЗА 2014. Т. 9. № 4 Medical news of north caucasus 2014. Vоl. 9. iss. 4 МЕДИЦИНСКИЙ ВЕСТНИК СЕВЕРНОГО КАВКАЗА 2014. Т. 9. № 4 Medical news of north caucasus 2014. Vоl. 9. iss. 4 МЕДИЦИНСКИЙ ВЕСТНИК СЕВЕРНОГО КАВКАЗА 2014. Т. 9. № 4 Medical news of north caucasus 2014. Vоl. 9. iss. 4