2018
DOI: 10.14300/mnnc.2018.13044
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Anemia in rheumatoid arthritis: correlation with hepcidin and adhesion molecules

Abstract: epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages.

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“…Activation/dysfunction of endothelium plays key role in the pathogenesis of RA, its manifestation, including the hyperproduction of adhesion molecules [6][7][8], responsible for the cellular migration, accumulation of immune cells and fibroblasts involved in the processes of destruction and proliferation of synovial membrane. Thus, in patients with RA increased plasma concentrations of molecules of immunoglobulin superfamily and selectins in severe course of disease was noticed, including with systemic (hematological) manifestations [6,7,9,10], which was not shared by other researchers [8].…”
mentioning
confidence: 87%
“…Activation/dysfunction of endothelium plays key role in the pathogenesis of RA, its manifestation, including the hyperproduction of adhesion molecules [6][7][8], responsible for the cellular migration, accumulation of immune cells and fibroblasts involved in the processes of destruction and proliferation of synovial membrane. Thus, in patients with RA increased plasma concentrations of molecules of immunoglobulin superfamily and selectins in severe course of disease was noticed, including with systemic (hematological) manifestations [6,7,9,10], which was not shared by other researchers [8].…”
mentioning
confidence: 87%