2001
DOI: 10.1590/s1415-52732001000300007
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Vitamina K: metabolismo e nutrição

Abstract: RESUMO RESUMO RESUMO RESUMO RESUMO O objetivo desta revisão foi discutir aspectos que envolvem a compreensão do metabolismo da vitamina

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Cited by 15 publications
(47 citation statements)
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References 51 publications
(50 reference statements)
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“…Osteocalcin is a low-weight molecular protein with three GLA residues produced by osteoblasts during bone matrix formation (Mijares et al, 1998). As one of the most abundant noncollagenous proteins of the extracellular bone matrix, its dosage in the blood is an important seric marker of bone formation (Dôres et al, 2001). Low level of vitamin K induces the synthesis of non-carboxyled osteocalcin that presents poor affinity for hidroxiapatite, leading to a deficient bone mineralization.…”
Section: Introductionmentioning
confidence: 99%
“…Osteocalcin is a low-weight molecular protein with three GLA residues produced by osteoblasts during bone matrix formation (Mijares et al, 1998). As one of the most abundant noncollagenous proteins of the extracellular bone matrix, its dosage in the blood is an important seric marker of bone formation (Dôres et al, 2001). Low level of vitamin K induces the synthesis of non-carboxyled osteocalcin that presents poor affinity for hidroxiapatite, leading to a deficient bone mineralization.…”
Section: Introductionmentioning
confidence: 99%
“…Dôres et al 42 relataram, em sua revisão, que a eficiência de absorção da vitamina K foi mensurada em 40% a 80%, dependendo do veículo no qual a vitamina é administrada, e que a fração excretada não depende da dose administrada.…”
Section: B I O D I S P O N I B I L I D a D E D A V I T A M I N A Kunclassified
“…Posteriormente, um estudo demonstrou que ratos alimentados com uma dieta deficiente em vitamina K apresentavam sinais de deficiência dessa vitamina, apesar de a quantidade de menaquinona encontrada no cólon estar aumentada, quando comparada ao grupo com dieta normal 46 . A importância da vitamina K, na alimentação, foi posteriormente confirmada em outros estudos [41][42][43] ; a maioria dos trabalhos não confirmou que a menaquinona, sintetizada pela microflora intestinal, é diretamente absorvida no cólon.…”
Section: B I O D I S P O N I B I L I D a D E D A V I T A M I N A Kunclassified
“…However, separation and detection by HPLC with electrochemical and fluorescence detectors after post-column reduction is relatively convenient and stable, and provides enough sensitivity and selectivity for analysing phylloquinone in plant products (Pérez-Ruiz et al, 2007;Jakob, Elmadfa, 2000). Brazil still has no tables Page 2 / 8 of phylloquinone levels for nationally produced foods (Dôres, Paiva, Campana, 2001). There is therefore a need to analyse Vitamin K levels in foods grown in Brazilian soil to assist researchers in the nutrition area, as studies have shown that geography can influence phylloquinone levels in analysed foods (Otles, Cagindi, 2007;Ferland, Sadawski, 1992).…”
Section: Introductionmentioning
confidence: 99%