Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method

Huang, Hong; Yang, Xiurong

doi:10.1016/j.carres.2004.08.005

Cited by 647 publications

(338 citation statements)

References 27 publications

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“…Biodegradable polymers like chitosan [24], cellulose [25] starch [26] and gum arabic [27]- [33] were also used as stabilizing agents in the preparation of AuNPs. Recently, lower concentrations of AuNPs have been explored by researchers for biomedical applications as it does not modify the chemical and photo-physical properties.…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

Parida¹,

Biswal²,

Bindhani³

2014

ABC

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In this investigation, the anticancer potentiality and biological mechanism of gold nanoparticles (AuNPs) was studied in SUDHL-4 cell line. Metallic AuNPs were prepared and stabilized with ethanol clove (Syzygium aromaticum) extract. The green synthesis of AuNPs was characterized and evaluated by UV-Visible Spectroscopic, X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS) and biological activities using various biochemical assays. Green synthesis of AuNPs was confirmed by instrument method. The TEM images show polydisperse, mostly spherical AuNPs particles of 12 -20 nm. AuNPs were decreased the growth and viability of SU-DHL-4 cell line and increased the apoptosis. The treatments of SU-DHL-4 cells with AuNPs resulted in a moderate considerably increase in Reactive oxygen species (ROS) production. We measured apoptosis by Annexin-V/propidium iodide (PI) in the existence and nonexistence of the antioxidant N-acetyl-Lcysteine (NAC), the glutathione-depleting agent buthionine sulfoximine (BSO), or caspase inhibitors to determine the mechanism of cell death. AuNPs are unique potential anticancer agents that cause ROS-dependent apoptosis in SUDHL-4 cell line which was improved by depletion of glutathione (GHS) and inhibited by N-acetyl-L-cysteine on Z-VAD-FMK.

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Section: Introductionmentioning

confidence: 99%

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

Parida¹,

Biswal²,

Bindhani³

2014

ABC

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“…Meanwhile, chitosan, is widely used (a natural polysaccharide deriving from chitin) because of its excellent properties, such as nontoxicity, biodegradability, biocompatibility and antibacterial character [23][24][25]. Another important property of chitosan is that the amino and hydroxyl groups can form chelate complex with silver ion [26].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of antimicrobial polymer composition and in vitro drugs release study

Tudorachi

2008

E-Polymers

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Abstract:The study presents a procedure to acquire a colloidal silver-based antimicrobial polymer composition. Carboxymethylstarch (CMS) as polymer matrix, and colloidal silver particles (Ag 0 ) obtained by in situ synthesis with silver nitrate and sodium citrate as reducing agent, were used. In solution, the presence of COOH and OH groups in carboxymethylstarch directs to silver complexation and acquirement of a stable suspension of silver particles. Due to the presence of colloidal silver particles, the composition presents bacteriostatic activity and in association with some drugs (acetylsalicylic acid or diclofenac sodium) pharmaceutical compositions can be obtained, which are useful in the prevention and treatment of some infections or diseases. The compositions were characterized by FTIR spectroscopy, UV-vis spectrophotometry, particle size analysis and zeta potential measurements. Drug release tests were done in vitro in phosphate buffer solution (pH=7.4, at 37 0 C).

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“…Metal nanoparticles preparation represents major area in nanoscale science and engineering to give unusual physical and chemical properties specially its catalytic activity, novel electronic and magnetic properties and their potential applications in bio nanotechnology [1,2].…”

Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

“…Metal nanoparticles generally prepared by chemical reduction of metal salts with chemical reducing agents such as citric acids, borohydrides, or other organic compounds [1,[3][4][5].These reducing agents cause cytotoxicity towards biological hazards. Green chemistry used to minimize or eliminate the waste and implement sustainable process [6].So that biological method used for prepare AuNPs.…”

Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

Green Synthesis, Cytotoxicity and Utilization of Carboxymethylchitosan-Stabilized Gold Nanoparticles.

Ibrahim¹,

Dakrory²,

Tawfik³

et al. 2017

IJAR

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Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method

Cited by 647 publications

References 27 publications

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

Synthesis of antimicrobial polymer composition and in vitro drugs release study

Green Synthesis, Cytotoxicity and Utilization of Carboxymethylchitosan-Stabilized Gold Nanoparticles.

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