Polyphenols profile and antioxidant activity of some Romanian Ranunculus species

Neag, Teodora Alina; Toma, Claudia Crina; Oláh, Neli-Kinga; Ardelean, Aurel

doi:10.24193/subbchem.2017.3.06

Cited by 9 publications

(12 citation statements)

References 6 publications

(7 reference statements)

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“…DPPH radical scavenging effect of R. sprunerianus hexane, ethyl acetate, methanol and aqueous extracts was found to be 27.60% ±0.06, 37.20% ±0.09, 85.34% ± 0.33 and 61.09% ± 0.29, respectively (Kaya et al, 2010). The IC50 value of the DPPH radical scavenging effect of R. ficaria extract obtained from glycerol-ethanol and hydroalcoholic solvents was calculated as 1.9 and 243.4 µl, respectively (Neag et al, 2017). When the results of this study are compared with A. hupehensis, A. spicata, C. europaea, H. foetidus, A. vulparia, T. altissimus, C. racemosa, R. sceleratus, R. marginatus var.…”

Section: Discussionmentioning

confidence: 86%

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Antimicrobial and Antioxidant effect of Ficaria verna Huds.

İnci

Eren

Kırbağ

et al. 2021

Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi

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Ficaria verna Huds. is a plant belonging to the Ranunculaceae family, known as mole grass and celandine among the people. It is known to have antiinflammatory and anti-haemorrhagic pharmaceutical effects. In this study, it was aimed to determine the antimicrobial effect of different concentrations of F. verna extracts obtained from methanol, ethanol and chloroform and the antioxidant activity of different concentrations of the extract obtained from methanol. In the results obtained, the best antimicrobial effect (17-20 mm) against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus megaterium, Salmonella thypii and Candida albicans was determined in the methanol extract of F. verna at a concentration of 1000 µg. It was observed that the scavenging effect of the DPPH radical of F. verna increased depending on increasing concentrations.

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Section: Discussionmentioning

confidence: 86%

“…Ficaria verna Huds., which belongs to the Ranunculaceae family, is used in folk medicine for anti-inflammatory and anti-haemorrhagic effects. Especially, tuberous and dry root parts of the plant are used in treatment (Neag et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antioxidant effect of Ficaria verna Huds.

İnci

Eren

Kırbağ

et al. 2021

Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi

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“…It was concluded that both the plant part and the extraction solvent created a significant difference. Especially, the difference in species significantly caused variability in the antioxidant activity and phenolic content (Neag et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Ranunculus gracilis Clarke Rizomunun In Vitro Biyolojik Aktiviteleri

Çil

Kasurka

Ayvaz

2022

Journal of Anatolian Environmental and Animal Sciences

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Ranunculus gracilis rhizomes were picked from Yenice Forests Karabük province in Turkey. Ethanol was chosen for extraction solvent. Disc diffusion method including filamentous and non-filamentous Gram-positive bacteria, Gram-negative bacteria, and yeast strains was used to evaluate the antimicrobial activity of the extract. 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and ferric reducing antioxidant power analysis were performed to determine antioxidant activity. The Folin-Ciocalteu method for determining the total phenolic amount and the AlCl3 method for the total flavonoid content of the extract was chosen. Mean diameters of inhibition zones (IZD) of the bacteria were found in the range of 8.2 mm to 24.45 mm. This value was measured as 17.82 mm and 18.69 mm for yeasts. The total antioxidant activity value of the extract was calculated as 7.08 mg AAE/g extract. The IC50 value was found as 9.097 mg/mL for DPPH free radical scavenging activity. The FRAP value indicated that the reducing power of 1 gram of sample was equivalent to 4.66 μmol of Trolox. The total phenolic content of ethanol extract of R. gracilis rhizomes was determined as 0.414 mg GAE/g, while the flavonoid content was calculated as 0.68 mgQE/g. This study is the first report demonstrating the biological activities of R. gracilis in the literature. The analyzed ethanolic extract of R. gracilis rhizomes demonstrated that the biological activity level could be considered significant according to the obtained results.

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“…The FRAP method evaluates the antioxidant capacity of a natural extract and is based on the change in color from light yellowish-green to blue of ferric tripyridyltriazine complex (Fe(III)TPTZ) and on the reduction of the ferric ion to the ferrous iron (Fe(II)) by a reductant, at an acid pH [ 78 ]. The calibration curve was made for concentrations between 0 and 300 μM, having a correlation coefficient R 2 = 0.9956 and the regression equation (y = 0.0017x + 0.0848), where y represents absorbance performed at 595 nm.…”

Section: Methodsmentioning

confidence: 99%

Physalis alkekengi L. Extract Reduces the Oxidative Stress, Inflammation and Apoptosis in Endothelial Vascular Cells Exposed to Hyperglycemia

et al. 2020

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To find new natural remedies in diabetes, this study investigated the biological activity of two extracts obtained from the fruits (PhyF) and herba (PhyH) of Physalis alkekengi var. franchetii L. on human umbilical vein endothelial cells (HUVECs) exposed to normo- and hyperglycemic conditions. The biological effect was quantified by malondialdehyde, IL-31 and IL-33 levels in correlation with physico-chemical characterization and antioxidant activity. Additionally, from PhyP extract, the caspase-3, IL-6, IL-10, tumor necrosis factor (TNF)-α and nuclear transcription factor NFkB expressions were evaluated. HPLC analysis revealed a significant number of phenolic compounds, especially in PhyF extract, with a good antioxidant activity as highlighted by TEAC, CUPRAC or DPPH methods. On HUVECS cells, the extracts were not toxic even at high concentrations. Particularly PhyF extract, diminished lipid peroxidation and inhibited the IL-31 and IL-33 secretions induced by hyperglycemia. The inhibitory effect on proinflammatory cytokines was noticed after both doses of PhyF extract in parallel with the upregulation of anti-inflammatory cytokine IL-10. Moreover, PhyF, especially in a low dose, reduced caspase-3 active form. These experimental findings suggest that Physalis fruits extract exerted beneficial effects in hyperglycemia by inhibition of oxidative stress, inflammation and apoptosis being a good adjuvant option in diabetes.

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Polyphenols profile and antioxidant activity of some Romanian Ranunculus species

Cited by 9 publications

References 6 publications

Antimicrobial and Antioxidant effect of Ficaria verna Huds.

Antimicrobial and Antioxidant effect of Ficaria verna Huds.

Ranunculus gracilis Clarke Rizomunun In Vitro Biyolojik Aktiviteleri

Physalis alkekengi L. Extract Reduces the Oxidative Stress, Inflammation and Apoptosis in Endothelial Vascular Cells Exposed to Hyperglycemia

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