Abstract:ResumoNos últimos anos, tem havido um interesse crescente a respeito de uma melhor compreensão sobre o comportamento anti-social. O aumento da criminalidade e violência urbanas pode ter contribuído para esse maior interesse. Além de fatores psicossociais, outros biológicos têm sido implicados na fisiopatogenia do transtorno de personalidade anti-social (TPAS). Estudos de neuroimagem apontam o envolvimento de estruturas cerebrais frontais, especialmente o córtex orbitofrontal, e a amígdala. Também tem sido suge… Show more
“…Abnormalities within the anterior-inferior regions of the temporal lobes are associated with violence. 4,7 Results of this research may serve as support to the growing evidence of brain dysfunction underlying the diagnosis of ASPD in subject authors of crimes. The use of non-invasive technology like the EEG appears to allow accurate identification of substantial CNS abnormalities.…”
Section: Discussionmentioning
confidence: 61%
“…1 Several studies indicate an interaction between biological factors and social factors in the development of antisocial behaviour. [2][3][4][5][6][7] In the last years there has been an increased interest in studying the neurobiology of personality disorders [8][9][10] , and in particular ASPD. 11,12 The brain regions more compromised in antisocial populations include frontal and temporal lobes.…”
“…Abnormalities within the anterior-inferior regions of the temporal lobes are associated with violence. 4,7 Results of this research may serve as support to the growing evidence of brain dysfunction underlying the diagnosis of ASPD in subject authors of crimes. The use of non-invasive technology like the EEG appears to allow accurate identification of substantial CNS abnormalities.…”
Section: Discussionmentioning
confidence: 61%
“…1 Several studies indicate an interaction between biological factors and social factors in the development of antisocial behaviour. [2][3][4][5][6][7] In the last years there has been an increased interest in studying the neurobiology of personality disorders [8][9][10] , and in particular ASPD. 11,12 The brain regions more compromised in antisocial populations include frontal and temporal lobes.…”
“…Tal transtorno constitui um padrão invasivo de desrespeito e violação dos direitos, iniciando na infância ou adolescência e continua na idade adulta (APA, 2002). Além disso, caracteriza-se pela impulsividade, expressa na dificuldade de planejar o futuro, através de escolhas que tragam a satisfação imediata e desconsideram as consequências e leis (Del-Bem, 2005). Desta forma, os tratamentos necessitam contemplar tanto o Transtorno por Uso de Substâncias, como o de Personalidade Anti-Social (Bordin & Offord, 2000).…”
Objetiva-se compreender o uso do crack e as características clínicas de mulheres, através da perspectiva de gênero. Trata-se de um estudo de caso, de caráter qualitativo. Participou deste estudo uma gestante usuária de crack, em internação hospitalar. Os instrumentos foram: entrevista semiestruturada; MINI 5.0; Screening Cognitivo do WAIS-III e SCID-II. As comorbidades encontradas foram: transtorno de ansiedade generalizada, episódio (hipo)maníaco passado e transtorno de personalidade antissocial. As funções cognitivas estavam preservadas. A gestação motivou a internação e a trajetória de vida permeada por violências e vulnerabilidades foi evidenciada, onde o preconceito dificultou o acesso ao tratamento.
“…1 It has a role in physiological (nerve transmission, immune response) and pathological processes (depression, stress, and sleep and appetite disorders) 2 and therefore its plasma levels are linked to changes in mood, behavior, anxiety, sleep, fatigue and appetite suppression. 3 These characteristics have led research centers to focus their studies on the creation of methods allowing the determination and quantification of this amino acid, as well as the identification of possible relationships between plasma levels of tryptophan with diseases and metabolic disorders.…”
Recebido em 15/6/11; aceito em 16/9/11; publicado na web em 3/11/11 A simple, rapid and selective method using high-performance liquid chromatography with ultraviolet detection (267 nm) was applied for the determination of tryptophan in plasma. Separation was carried out on a C18 column (150 x 4.6 mm internal diameter) in 6 min. The mobile phase consisted of 5 mM the sodium acetate and acetonitrile (92:8, v/v). The method was shown to be precise and accurate, and good recovery of analyte was achieved, characterizing the method as efficient and reliable for use in laboratory analysis.
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