Contribuição ao estudo fitoquímico de Dorstenia multiformis Miquel (Moraceae) com abordagem em atividade antioxidante

Balestrin, Luciana; Dias, June Ferraz; Miguel, Obdúlio Gomes; Dall'Stella, Daniela Saboia Gruber; Miguel, Marílis Dallarmi

doi:10.1590/s0102-695x2008000200016

Cited by 24 publications

(22 citation statements)

References 17 publications

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“…23,24 Comparison of the sample with a standard mixture of a-and b-amyrin by gas chromatography confirmed the presence of these two structures (b-amyrin Tr = 19.1 min and a-amyrin Tr = 20.7 min), and the b-amyrin was found in greater quantity, at a ratio of 3:1. Retention times were similar to those observed when these triterpenes were analyzed in mixture.…”

Section: Resultsmentioning

confidence: 83%

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Magina¹,

Dalmarco²,

Dalmarco³

et al. 2012

Quím. Nova

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Recebido em 10/10/11; aceito em 17/1/12; publicado na web em 15/5/12 A chemical investigation of Eugenia brasiliensis Lam. (Myrtaceae) leaves led to the isolation of a-amyrin and b-amyrin (in a mixture), betulin, 29-hydroxy-oleanolic acid, quercetin, catechin and gallocatechin. Herein, the identification of 29-hydroxy-oleanolic acid is reported for the first time in the Myrtaceae family. Moreover, in this study, the extract, fractions and six of the seven compounds were monitored for toxicity toward Artemia salina, antibacterial and acetylcholinesterase inhibitory activity. The crude ethanol extract of the leaves and fractions were found be active on A. salina toxicity bioassay.

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Section: Resultsmentioning

confidence: 83%

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Magina¹,

Dalmarco²,

Dalmarco³

et al. 2012

Quím. Nova

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“…De acordo com a literatura, estudos mostram que tanto óleos essenciais (Souza et al, 2007) como componentes não voláteis (extratos), extraídos de plantas (Balestrin et al, 2008, Nunes et al, 2008, têm sido estudados quanto à a avaliação do seu potencial antioxidante, demonstrando alta eficiência.…”

Section: Introductionunclassified

Metabólitos Secundários e ação antioxidante de Croton helliotripifolius e Croton blanchetianus

et al. 2017

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ResumoAntioxidantes são compostos que reagem com os radicais livres controlando o estresse oxidativo. Muitas doenças estão associadas à produção de radicais livres, os quais tem estimulado investigações do potencial antioxidante de diversas famílias da flora mundial. Essa pesquisa teve como objetivo identificar as principais classes de metabólitos secundários presentes nos estratos etanólicos das folhas de Croton blanchetianus (Marmeleiro) e Croton heliotropiifolius (Velame), e avaliar o seu potencial antioxidante. Os estratos etanólicos foram obtidos das folhas, apresentou um rendimento de 3,29% e 3,26%. Em seguida, os estratos foram submetidos a análise fitoquímica, nos quais foi possível identificar a presença de taninos condensados, flavonoides, flavononas, flavonóis, flavononóis, catequinas e xantonas. A atividade antioxidante dos estratos foi determinada pelo método fotocolorimétrico in vitro realizada por meio do sequestro de radicais livres, usando o DPPH (1,1-difenil-2-picrilhidraliza). Ambos os estratos foram capazes de sequestrar o radical livre DPPH, sendo que o estrato de Croton blanquetianus mostrou ser mais eficiente do que o BHT (Hidroxitolueno butilado; controle positivo), com CE50 = 6,5 ± 0,5 mg mL -1 . Contudo, os resultados observados para os estratos etanólicos, possivelmente sejam atribuídas à presença e a concentração de compostos fenólicos pertencentes as classes dos taninos e flavonoides, os quais foram identificados nesse estudo. Palavras-chave: Radicais livres, fitoquímica, fotocolorimétrico Secondary metabolites and antioxidant action of Croton heliotropiifolius andCroton blanchetianus Abstract Antioxidants are compounds that, at optimal concentrations in relation to oxidable substrates, react with free radicals preventing or reducing oxidative stress. Many diseases and degenerative processes are associated with overproduction of free radicals. This stimulated several research groups to investigate the antioxidant potential of substances produced by several families of the world flora. This study identified the major classes of secondary metabolites present in ethanol leaf extracts of C. blanchetianus (Marmeleiro) and C. heliotropiifolius (Velame), and assessed their antioxidant potential. Ethanol extracts were obtained by the exhaustive extraction method cold and resulted in 3.29% and 3.26% extraction efficiency. Then phytochemical analyses were performed on the extracts to investigate the presence of tannins, flavonoids, flavonones, flavonols, catechins and xanthones. The antioxidant activity of extracts was determined by in vitro photocolorimetric method based on the sequestration of free radicals, using DPPH (1,1-diphenyl-2-picryl-hydrazyl). Both extracts were able to sequestrate DPPH free radical. Croton blanchetianus extract activity showed to be more efficient than BHT (Butylated Hidroxytoluene) (positive control), with EC50 = 6.5 ± 0.5 mg mL -1 . Croton heliotropiifolius extracts showed lower antioxidant activity, with EC50 = 50.15 ± 0.21 but still higher than that observed fo...

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“…Tanto óleos essenciais (Baratta et al, 1998;Ruberto & Baratta, 2000;Morais et al, 2006;Souza et al, 2007) como componentes não voláteis (extratos), extraídos de plantas (Weng & Wang, 2000;Fenglin et al, 2004;Miliauskas et al, 2004;Andrade et al, 2007;Sousa et al, 2007;Balestrin et al, 2008;Nunes et al, 2008), têm sido estudados quanto à avaliação do seu potencial antioxidante, demonstrando alta eficiência.…”

Section: Introductionunclassified

Ação antioxidante de chás e condimentos de grande consumo no Brasil

Morais¹,

Cavalcanti²,

Costa³

et al. 2009

Rev. bras. farmacogn.

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"Antioxidant action of teas and seasonings more consumed in Brazil". Antioxidants are compounds that remove free-radicals or minimize their availability to generate oxidative stress. Teas are popular beverages providing a significant source of phenolic compounds, important components of the human diet due to their antioxidant properties. The present work had the objective of evaluate the antioxidant action of teas and seasonings more consumed in Brazil. The analysed teas were from the plants: Pneumus boldus Mold., Matricaria recutita L., Cymbopogon citratus (DC) Stapf, Baccharis trimera (Less.) DC, Camelia sinensis (L) O. Kuntze (fermented), Camelia sinensis (not-fermented), Lippia alba N.E. Brown, Mentha arvensis L. and Pyrus malus L. The studied seasonings were: Eugenia aromatica Baill, Cinnamonum zeylanicum Blume, Laurus nobilis L. and Origanum vulgare L. The antioxidant activity was measured by the DPPH free radical scavenging method. All analysed samples demonstrated antioxidant activities. Camelia sinensis (not-fermented) (IC 50 = 0.14 mg/mL), was the most active and active principles are epicalocatechins. The stronger antioxidant seasonings were Cinnamonum zeylanicum (IC 50 = 0.37 mg/mL), Eugenia aromatica Baill (IC 50 = 0.46 mg/ mL and Laurus nobilis (IC 50 = 0.76 mg/mL), which presented as main antioxidant component eugenol.

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Contribuição ao estudo fitoquímico de Dorstenia multiformis Miquel (Moraceae) com abordagem em atividade antioxidante

Cited by 24 publications

References 17 publications

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Metabólitos Secundários e ação antioxidante de Croton helliotripifolius e Croton blanchetianus

Ação antioxidante de chás e condimentos de grande consumo no Brasil

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