Atividade antimicrobiana in vitro de produtos vegetais em otite externa aguda

Abstract

Acut e Otitis Externa is an inflammation of the outer auditory meatus, and according to popular saying, medicinal plant extracts can be used in its treatment. Aim: to assess the in vitro antimicrobial activity of the following plants: Aleolanthus suaveolens; Caryophyllus aromaticus; Cymbopogon citratus; Matricaria chamomila; Pithecellobium avaremotemo; Plectranthus amboinicus and Ruta graveolens on the germs that cause otitis externa. Materials and Methods: the minimum inhibitory concentration of extracts and oils from these plants was obtained from otitis externa samples. Results: Staphylococcus aureus in 10 cultures, Pseudomonas aeruginosa in 8, Pseudomonas aeruginosa and Staphylococcus aureus together in 5 cultures and Candida albicans and Candida krusei in 4 cultures. P. aeruginosa was resistant to all oils and extracts tested; extracts from A. suaveolens, P. avaremotemo and R. graveolens were inactive; the essential oil from C. aromaticus and M. chamomila were active against 3 strains of S. aureus and the Candida strains; seven of the S. aureus strains were sensitive to the P. amboinicus extract; however, the oil was inactive against 4 S. aureus strains and the Candida strains were sensitive to the R. graveolens essential oil. Conclusion: depending on the etiological agent, some plants presented satisfactory results, however we still need more detailed studies in order to better use these plants.

A screening for antimicrobial activities of Caribbean herbal remedies

“…For instance, the antimicrobial effects of hydroalcoholic extracts from the leaves of Plectranthus amboinicus have been reported against S. aureus with a MIC of 9.3 mg/mL [35]. In another study [36], seven out of ten S. aureus strains obtained from exudates of otitis externa were sensitive to P. amboinicus extracts at concentrations ranging from 1.25 to 5.0 mg/mL. In particular, the essential oil of P. amboinicus was active against two of the strains tested at 4% and 8% (w/V).…”

Atividade antimicrobiana de extratos hidroalcoolicos das folhas de alecrim- pimenta, aroeira, barbatimão, erva baleeira e do farelo da casca de pequi

“…Outros estudos relatam a ação antimicrobiana de extratos de barbatimão (COWAN, 1999;QUEIROZ et al, 2002;CUNHA, 2006) e, na medicina popular, ele é usado no tratamento de úlceras, afecções vaginais e gonorreia, devido às suas propriedades cicatrizantes, anti-inflamatórias, hemostáticas, anti-sépticas, anti-diarreicas e antiedematogênicas (QUEIROZ et al, 2002). A maior parte dos trabalhos que confirmam a atividade antimicrobiana do barbatimão tem sido realizada com cascas e raízes (ORLANDO, 2005;SANTOS et al, 2007;NOGUEIRA et al, 2008), sendo que, no presente estudo, esta propriedade foi comprovada com as folhas da espécie.…”

Interferência de extratos da Baccharis dracunculifolia DC., Asteraceae, sobre a atividade de antibióticos usados na clínica

“…O óleo essencial foi estudado na concentração de 8%, correspondendo a CIM determinada em pesquisas anteriores (Ceballos et al, 1993;Lima et al, 2003;Araújo et al, 2004;Nogueira, 2004;Ferronato et al, 2007aFerronato et al, , 2007b, incluindo os mesmos microrganismos ensaiados neste estudo, já em relação às concentrações dos dois extratos foram utilizadas as (CIM) recomendadas em pesquisas anteriores (Pires, 2008), que indicaram 50% para o extrato hidroalcoólico e 25% para a fração apolar.…”