2009
DOI: 10.1590/s1808-18512009000300015
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Effects of hyperbaric oxygen therapy after spinal cord injury: systematic review

Abstract: OBJECTIVE: to conduct a systematic review of experimental and clinical studies evaluating the effect of hyperbaric oxygen therapy on the spinal cord injury. METHODS: ninety-three studies were identified in the database Pubmed. Among these, through a set of inclusion/exclusion criteria, 11 articles published between 1963 and 2009 were selected. In the nine experimental studies, different ways to apply the treatment were observed. The measured outcomes were: functional, histological, biochemical and electrophysi… Show more

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Cited by 8 publications
(7 citation statements)
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“…After the primary mechanical lesion on the spinal cord, a cascade of events leads to secondary degeneration and death of the potentially viable neuronal tissue [16][17][18] . Among the components of the secondary lesion, hypoxia/ischemia is considered of utmost importance to spinal tissue injury, impairing the physiological medullar mechanism and its encephalic connections.…”
Section: Infertility On the Sci Patientmentioning
confidence: 99%
See 2 more Smart Citations
“…After the primary mechanical lesion on the spinal cord, a cascade of events leads to secondary degeneration and death of the potentially viable neuronal tissue [16][17][18] . Among the components of the secondary lesion, hypoxia/ischemia is considered of utmost importance to spinal tissue injury, impairing the physiological medullar mechanism and its encephalic connections.…”
Section: Infertility On the Sci Patientmentioning
confidence: 99%
“…The healing process of the tissues damaged by trauma is divided into three phases: inflammatory, proliferative and remodeling. It is important to note that oxygen is an indispensable component of the repairing process 16 .…”
Section: Infertility Therapymentioning
confidence: 99%
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“…A incidência desse tipo de lesão é bastante variada nos diferentes países, e ainda não é bem definida no Brasil por não ter uma notificação eficaz dos casos e pela escassez de estudos epidemiológicos significativos 2 . Existem poucos dados sobre o TRM no Brasil, onde se estima uma incidência de 10.000 novos casos por ano, principalmente devido ao trauma 4 . Em muitos países a lesão da medula espinhal ocorre em uma taxa anual de 20-40 indivíduos por milhão.…”
Section: Revisão Introduçãounclassified
“…Em relação à fisiopatologia do TRM, após a lesão mecânica primária, uma cascata de eventos é observada, o que leva à degeneração e morte do tecido potencialmente viável neuronal. Entre os componentes a lesão secundária, isquemia/hipóxia é considerado um dos fatores mais importantes implicados na lesão do tecido neuronal 4 . Na maioria dos casos de trauma raquimedular o mecanismo da lesão primária é a compressão aguda ou a laceração da medula espinal devido ao deslocamento ósseo ou hérnia de disco, após o deslocamento ou explosão da fratura 3 .…”
Section: Revisão Introduçãounclassified