2004
DOI: 10.1590/s1516-84842004000100008
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Transplante de células-tronco hematopoéticas no diabete melito do tipo I

Abstract: Transplante de células-tronco hematopoéticas no diabete melito do tipo I Autologous hematopoietic stem cell transplantation in type I diabetes mellitus Júlio C. Voltarelli Transplantes autólogos de células-tronco hematopoéticas (TACTH) para doenças auto-imunes (DAÍ) graves e refratárias à terapia convencional têm sido realizados desde 1996, principalmente dirigidos a doenças reumáticas e neurológicas, com resultados encorajadores. De modo geral, dois terços dos pacientes alcançam remissão duradoura da doença a… Show more

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Cited by 13 publications
(14 citation statements)
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References 6 publications
(7 reference statements)
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“…É realizada então a coleta propriamente dita, que pode ser com placenta intrauterina ou extrauterina e mista, em qualquer tipo de parto (Brasil, 2004;Voltarelli, Pasquini & Ortega, 2009;Santos, Marti, Ribeiro, Conti & Barros, 2011).…”
Section: Conhecimentosunclassified
“…É realizada então a coleta propriamente dita, que pode ser com placenta intrauterina ou extrauterina e mista, em qualquer tipo de parto (Brasil, 2004;Voltarelli, Pasquini & Ortega, 2009;Santos, Marti, Ribeiro, Conti & Barros, 2011).…”
Section: Conhecimentosunclassified
“…[8][9] The conditioning phase can be highlighted among the decisive steps throughout the HSCT process, in which the patient receives chemotherapy and/or radiotherapy to cause medullary aplasia and induce immunosuppression with the purpose of avoiding rejection of the new grafted bone marrow. [10][11] At this stage, the patient suffers from symptomatologies arising from the administered drugs, and gastrointestinal disorders are common.…”
Section: Introductionmentioning
confidence: 99%
“…[11][12] At this stage, mucositis can be intensified causing pain and discomfort, making speech and swallowing difficult. These symptoms have disabling potential and weaken the patient, negatively interfering in their QoL.…”
Section: Introductionmentioning
confidence: 99%
“…The Hematopoietic Stem Cell Transplantation (HSCT) is a treatment modality used more frequently for oncology and hematological diseases genetically inherited or acquired [1][2]. The HSCT may occur by autologous transplantation, when Hematopoietic Progenitor Cells (HPC) are from the patient; allogeneic when HPC come from donors with compatible Human Leukocyte Antigen (HLA), related when they are of the same family and not related if it is not from an inbred donor; or syngeneic transplantation, when HPC are from identical twins [3].…”
Section: Introductionmentioning
confidence: 99%
“…The graft-versus-host disease (GVHD) is presented as the main complication after HSCT, more frequently in allogeneic transplantations [1][2][3]. This can affect many organ systems and cause consequences to transplant patients, both in an acute form, in the first 100 days after HSCT as in the chronic form after this period [4].…”
Section: Introductionmentioning
confidence: 99%