Lung compliance and functional residual capacity were determined in the erect standing and the supine lying positions on six normal adults. Both lung compliance and functional residual capacity were proportionally reduced on resuming the supine from the standing position so that the ‘specific compliance’ remained the same at the two body positions. The correlation between lung compliance and FRC found in this study agrees well with that reported by others and the importance of considering the size of the system in assessing elastic properties of the lung is briefly discussed. Submitted on October 17, 1958

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The combination of DA and NAL exhibits an additive effect for both the viscoelasticity and transportability of CF sputum samples. The two agents appear to act well together in breaking down the bonding due to extracellular DNA and mucins. Clinical studies should be undertaken to see whether the additive combination at lower concentration produces the anticipated benefits of improved airway clearance and fewer side effects.

Since 1997, more than 600 individuals worldwide have been infected with the poultry-originating influenza, H5N1. This report describes the first case of avian influenza A (H5N1) in the Western hemisphere in a 28-year-old woman who had just returned from a trip to Beijing, China. The typical manifestations of H5N1 are described, and signs and symptoms are discussed.