AbstractsBackgroundEven though, the disclosure of HIV sero- status to sexual partners, friends or relatives is the main tool for prevention and care strategies, most of the HIV/AIDS patients do not inform their close friends. The most common reasons for not disclosure of their status to the community were majorly fear of social rejection and discriminations. Therefore, this study assessed the HIV positive sero-status disclosure and its determinants among People Living with HIV /AIDS (PLWH/A) followed by the Antiretroviral therapy (ART) Clinic in Jimma University Specialized Hospital, Southwest Ethiopia.MethodsA facility based cross-sectional study design was used among 351 ART patients that selected by systematic random sampling from ART clinic of Jimma University Specialized Hospital in March-2014. Data were collected through interviewer-administered questionnaires and analyzed using SPSS version 20.0 software. In a descriptive analysis frequency, mean and percentage were calculated. Bivariate and multivariate analyses were used to identify associated factors and the association between the explanatory and dependent variables was estimated.ResultsOnly 37.6% (n = 132) were revealed their HIV positive status to anyone. Disclosure was done towards the sexual partners (88.6%), close family (72.7%) and a larger population (18.2%). Age ≤ 39 years (AOR = 0.014 [95%, CI = 0.005, 0.037]),Male sex (AOR = 3.039, [95% CI = 1.164, 7.935]), WHO stage III – IV at ART start(AOR = 2.766, [95%, CI = 1.321, 5.791]), presence of comorbidity (AOR = 2.500, [95%, CI = 1.483, 4.214]), having any clinical symptoms for HIV(AOR = 2.98, [95%, CI = 1.724, 5.152]),Low physical domain related quality of life (AOR = 3.83, [95%, CI = 2.008, 7.315]) and high social domain related quality of life (AOR = 0.053, [95%, CI = 0.022, 0.125]) were statistically significant association with their HIV sero-status disclosure.ConclusionsFindings of this study indicated, the disclosure of HIV status is very low. Discloser is more likely when the patient is older, male, and has a higher level of education. Clinical determinants for disclosure was the WHO stage III-IV, treatment duration of ≥2 years, comorbidity, presence of clinical symptoms for HIV, low physical domain related quality of life, low social domain related quality of life and low overall quality of life.
Background Neonatal sepsis, which resulted from bacterial, viral, and fungal invasions of the bloodstream, is the major cause of neonatal mortality and neurodevelopmental impairment among neonates. It is responsible for more than one-third of neonatal deaths in Ethiopia. Frequently neonates referred to health facilities are at high risk of death. Hence, assessing and preventing the predictors of mortality in neonatal sepsis helps to reduce the burden of neonatal mortality. Objectives To determine predictors of mortality among neonates admitted with sepsis at Durame general hospital, southern Ethiopia, 2020. Methods Institution-based unmatched case-control study was carried out from March 8 to 30, 2020, among 219 neonates in Durame general hospital in southern Ethiopia. Neonates admitted with sepsis and died were considered as cases and neonates admitted with sepsis and survived (discharged alive) as controls. Cases were selected by taking the deaths of neonates consecutively among those neonates admitted with the diagnosis of neonatal sepsis. The next immediate three corresponding controls were selected by lottery method from the Neonatal Intensive Care Unit (NICU) case registration book. Data was collected by using structured pretested checklists from neonates’ records and then entered into Epi data version 3.1 and exported to SPSS version 20. Logistic regression was used to identify the predictors of mortality. Statistical significance was declared at P < 0.05. Results A total of 55 cases and 164 controls were included in this study. More than three quarters (81.8%) of cases had early onset sepsis. The multivariable logistic regression analysis showed that predictors of mortality in this study were; poor feeding [AOR = 4.15; 95% CI (1.64, 10.49)], respiratory distress [AOR = 2.72; 95% CI (1.31, 5.61)], estimated gestational age less than 37 weeks [AOR = 4.64; 95% CI (2.17, 9.91)], and convulsion [AOR = 3.13; 95% CI (1.12, 8.76)]. Conclusion This study showed that prematurity, convulsion, poor feeding, and respiratory distress were the predictors of sepsis-related neonatal mortality. It is important to pay attention to septicemic babies with any of the identified predictors to reduce sepsis-related mortality.
Objective This study assessed the outcome of tuberculosis treatment and associated factors in Bale Zone, Southeast Ethiopia in 2017. Methods This was 5-year retrospective study of a health registry for tuberculosis patients, which was reviewed from 1 September 2011 to 30 August 2016. Data were analyzed, and descriptive and logistic regression analyses were used to identify the factors that were associated with tuberculosis treatment outcomes. Results Among the 7205 tuberculosis patients, 6325 (87.8%) had a successful treatment outcome and 880 (12.2%) had an unsuccessful outcome. The age groups ≤14 years (adjusted odds ratio [AOR]=2.21), 15 to 24 years (AOR=1.61), 25 to 34 years (AOR=1.86), or 35 to 44 years (AOR=1.65); being treated at a hospital (AOR=1.63) or health center (AOR=2.52); pulmonary tuberculosis-positive (AOR=0.80); or extrapulmonary tuberculosis patients (AOR= 0.78) were the factors that were significantly associated with tuberculosis treatment outcome. Conclusions Public health facilities should pay special attention to the identified variables for tuberculosis prevention and control activities, especially focusing on supporting health workers who work at a health post (lowest level of Ethiopia’s three-tiered healthcare system).
Background:HIV care of people living with HIV /AIDS (PLWH/A) is critical for fruitful HIV inhibition, treatment and provision of quality of life. The goal of Anti-Retroviral Therapy (ART) is to suppress viral replication, lessen morbidity and death, and improve patients’ quality of life. The quality of life of HIV/AIDS patients is not well appraised in the study area beforehand. Therefore, this study assessed the health-related quality of life and associated factors among people living with HIV /AIDS followed by ART Clinic in Jimma University Specialized Hospital, Southwest Ethiopia.Methods:We used facility based cross-sectional study design and 351 samples selected by systematic random sampling from Jimma University Specialized Hospital ART clinic in March-2014. Data were collected through interviewer-administered questionnaires and analyzed by using SPSS version 20.0 software. Descriptive analysis (frequency and percentage) was calculated. Bivariate and multivariate analyses were used to identify associated factors. The association between the explanatory and dependent variables was assessed at p-value of less than 0.05. The results were presented in a narrative form, tables and graphs.Results:From the total respondents, 143 (40.7%) of them have low quality of life in general. Of these, 238 (67.8%) of them had low psychological domain, 136 (38.7%) had low physical domain and 223 (63.5%) low social domain. The age ≤ 39 years (AOR = 2.381 [95% CI = 1.238, 4.579]), Currently employed (AOR= 3.509 [95% CI = 1.900, 6.482]), current CD4 count ≥ 250 cell/ml (AOR = 2.663 [95% CI = 1.363,5.203]), current WHO Stage I-II (AOR = 4.772 [95% CI = 2.308, 9.865]), good general health condition (AOR = 2.609 [95%CI = 1.372, 4.961]), no comorbidity (AOR = 7.737 [95% CI = 4.146, 4.438), friendly social relationship (AOR = 5.395 [95% CI = 2.781, 10.467]), other persons reminded their drugs took time (AOR = 3.363 [95% CI = 1.629, 6.943]) and drunk alcohol (AOR = 1.915[95% CI = 1.039, 3.529]) were identified as the predictors of health related quality of life.Conclusion:Findings of this study indicate that the significant number of participants exists on low-level- of health related quality of life in general. The age, occupation, current CD4 count level, current WHO stage status, general health conditions, comorbidity conditions, status of their social relations, their conditions due to lack of support, reminder of drugs taking time, and alcohol drinking status have been observed to have a statistically significant association with their health-related quality of life status.
Background: Colostrum is the first breast milk produced after birth and is important for promotion of health and prevention of infections of the newborn. Though breastfeeding practices are well known but the necessity of colostrum feeding is still poorly understood by mothers.Objective: To assess Knowledge, Attitude, Practices and associated factors towards colostrum feeding among mothers of infants in ambo district of west Shoa zone, Oromia, Ethiopia.Methods: A community-based cross-sectional study was conducted from March to April 2019 among 429 mothers of infants selected by simple random sampling technique. The data were collected using structured questionnaire, focus group discussion & key informant interview by semi structured guiding questionnaire. Descriptive analysis like frequency, percentage, & mean were performed. Binary and multiple logistic regression analysis were employed to identify associated factors. Variables with p-value <0.05 with 95% confidence interval identified statistically significant.Results: Among the respondents, 278 (64.8%) mothers had good knowledge & 250 (58%) had favorable attitude. But colostrum feeding was practiced only by 227(56.5%). Mothers of neonates without any illness/finding at birth (AOR =14.87 [ 95% CI: 5.00-44.27]) & postnatal care within the first 2-3 days (AOR = 3.48 [95% CI: 1.23-9.85]) were positively associated factors; but unwanted pregnancy/birth (AOR = 0.243 [95% CI: .113-.527]), mothers suffering from any health problems during pregnancy/birth (AOR = 0.380 [95% CI: .161-.903]), lack of counseling (AOR = 0.264 [95% CI: .103-.675]), home delivery (AOR = 0.239 [95% CI: .111-.516]), & lack of information on colostrum (AOR = 0.040 [95% CI: .013-.125]) were negatively associated with colostrum feeding practices. Conclusions: Majority of respondents had good knowledge & favorable attitude but with poor practices of colostrum feeding. Good neonatal health at/soon after birth & postnatal care attendance within two to three days were positively associated with colostrum feeding practices. But, unwanted pregnancy/birth, any sickness of mother at birth/during pregnancy, lack of counseling on colostrum feeding, home delivery, & lack of information on colostrum feeding were less likely to feed colostrum.Strengthening family planning service, antenatal care, institutional delivery, postnatal care, information provision for counseling & the revision of DHIS2 for inclusion of colostrum feeding indicators were recommended interventions.
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