Background The Shenkursk Injury Registry (SHIR) was established in the Shenkursk District, Northwestern Russia in 2015 for the purposes of primary prevention. The SHIR covers all injuries (ICD-10 diagnoses from S00 to T78) for which medical aid is given at the Shenkursk central district hospital and includes data about injury circumstances. We used the SHIR data to assess the quality of the SHIR as an evidence basis and for the local preventive applications. Methods Completeness, representativeness, and reliability of the SHIR data were assessed using a sample of 1696 injuries which have occurred in July 2015–June 2016. Chi-square tests were used to assess differences between the registered and missed cases in the registry and Cohen’s kappa were applied to assess the agreement between independent data entries. Results The completeness of the SHIR with respect to the coverage of cases treated at the Shenkursk central district hospital was 86%. There were no differences between the registered and the missed injuries by sex, ICD-10 codes, weekday of admission, but there were differences in their distribution by attending physicians. Also, higher proportions of child injuries and injuries in the summer time were among the missed cases. Signs of lower injury severity (different distribution by ICD-10 codes and lower proportion of traffic injuries) were observed among injuries in rural areas which were not covered by the registry because of treatment at rural primary health care units without referrals to the central hospital. Two independent data entries from standard paper injury registration forms showed a 79–99% agreement, depending on the variable considered. Conclusion With consideration of possible insubstantial overestimates of the average injury severity, the SHIR data can be considered sufficiently complete, reliable, and representative of the injury situation in the Shenkursk District. Therefore, SHIR is an adequate evidentiary basis for planning local injury prevention.

This study aimed to investigate associations between the weather conditions and the frequency of medically-treated, non-fatal accidental outdoor fall injuries (AOFIs) in a provincial region of Northwestern Russia. Data on all non-fatal AOFIs that occurred from January 2015 through June 2018 (N = 1125) were extracted from the population-based Shenkursk Injury Registry (SHIR). Associations between the weather conditions and AOFIs were investigated separately for the cold (15 October–14 April) and the warm (15 April–14 October) seasons. Negative binomial regression was used to investigate daily numbers of AOFIs in the cold season, while zero-inflated Poisson regression was used for the warm season. The mean daily number of AOFIs was 1.7 times higher in the cold season compared to the warm season (1.10 vs. 0.65, respectively). The most typical accident mechanism in the cold season was slipping (83%), whereas stepping wrong or stumbling over something was most common (49%) in the warm season. The highest mean daily incidence of AOFIs in the cold season (20.2 per 100,000 population) was observed on days when the ground surface was covered by compact or wet snow, air temperature ranged from −7.0 °C to −0.7 °C, and the amount of precipitation was above 0.4 mm. In the warm season, the highest mean daily incidence (7.0 per 100,000 population) was observed when the air temperature and atmospheric pressure were between 9.0 °C and 15.1 °C and 1003.6 to 1010.9 hPa, respectively. Along with local weather forecasts, broadcasting warnings about the increased risks of outdoor falls may serve as an effective AOFI prevention tool.

Paramount problems of the development of the assessment of population health risks associated with the chemical exposure in Russia are considered on the ground of critical analysis of reports devoted to methodological issues of the risk assessment and guidelines published since 2010. Causes of the lack in progress of risk assessment are discussed. The information of executed research revealed the significant retardation number of Russian publications devoted to the evidence-based health risk assessment compare to worldwide trend. The analysis of publications according to evidence-based health risk assessment in Russia in 1998 - 2012 demonstrated methodical problems to be leading to the underestimation of the real risk to population’s health. There are demonstrated directions in the renewal of methodology and practice of hygienic standardization on the basis of the risk assessment. The comparative analysis of values of uncertainty factors (modifying factors, conversion factors) used for extrapolation and accepted in different countries and organizations was made. The system of extrapolation coefficients of DNEL (Derive No-Effect Level) is presented. The leading principles of modern toxicology and risk assessment based on strict scientific proofs are showed. Criteria of evidence-based toxicology and risk assessment are presented.Among actual problems which demand their decision there are considered: the assessment of combined action in regulatory toxicology; expansion of spheres of the application of health risk assessment methodology; the improvement ofpreparation and certification of experts in the field of health risk assessment; need of check of dispersion models and their replacement by more modern models; the improvement of exposure assessment with taking into account the international requirements; the assessment of regional exposure factors; expansion of atmospheric air monitoring in all the large cities of Russia

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Assessment of soil biological pollution and epidemic hazard in the Arkhangelsk region was carried out using the monitoring data in 2007–2015. The dangerous soil pollution by microorganisms of E. coli group was in Arkhangelsk, Novodvinsk and six districts, by fecal streptococcus was in Kotlas. Arkhangelsk, Severodvinsk, Novodvinsk and nine districts were territories with moderately dangerous of soil pollution by eggs, larvae of ascarids and toxocara. The level of soil contamination by microorganisms in the territory of medical and preventive treatment facility, dwellinghouses and recreation area was higher in comparison with the territory of child care facilities. The highest level of soil contamination by total biological agents connected with municipal solid waste production was registered in the residential area in Kotlas, towns and districts of the Arkhangelsk agglomeration.

Aims: This study aimed to compare the concentrations of heavy metals in reindeer and cow meat and offal originating from the Nenets Autonomous Okrug, Northwestern Russia, and to assess the risk to the health of the indigenous population associated with heavy metal intake due to the consumption of reindeer and cow. Methods: Lead, cadmium, mercury, and arsenic concentrations were measured in 39 muscle, 15 liver, and 14 kidney samples from reindeer and 33, 18, and 12 corresponding samples from cow in 2014–2016 using atomic absorption spectrometry. Estimated daily intake of investigated heavy metals, hazard quotient, hazard index and cancer risk were calculated. Results: Mean cadmium and mercury concentrations in reindeer liver and kidney exceeded the maximum permissible levels for bovine animals. However, the estimated daily intakes of heavy metals through consumption of reindeer and cow meat and offal were lower than tolerable daily intakes. Hazard quotient and hazard index values for heavy metals in reindeer and cow samples were <1. Hazard index values were in descending order: reindeer kidney (0.389)>reindeer muscle (0.382)>cow muscle (0.088)>reindeer liver (0.051)>cow kidney (0.012)>cow liver (0.004). The cancer risk related to the consumption of reindeer and cow meat and offal did not exceed acceptable levels. Conclusions: There is no human health risk associated with heavy metal intake due to the consumption of reindeer and cow meat and offal originating from the Nenets Autonomous Okrug.

Hygienic assessment of chemicals’ level in food products and health risk assessment of the population in Arkhangelsk region were carried out. Levels of heavy metal contamination of certain food groups do not exceed allowable hygienic standards. Non-cancer risk was high for a hormonal system (HI = 3,9), nervous (HI = 3,4) and immune (HI = 3,2) systems, skin (HI = 3,2). The priority pollutants of food products were arsenic and lead. Total cancer risk was high (CR = 1,4 × 10-3) and could be associated with fish contamination by inorganic arsenic (44,0 %).