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There are around 60 global species including genus Sesbania, which are commonly available. The leaves of Sesbania grandiflora is used as local traditional medicine. Most of all parts of plant of S. grandiflora are used in traditional medicine as well as phytochemical investigations, seeds and roots of Sesbania grandiflora to provide scientific validation of its properties. The family of Sesbania grandiflora is fabaceae and is widely used as a traditional Indian medicine. The common name of plant Sesbania grandiflora is Agate, as well as crook wood. Various chemical constituents present in plant contain tannins, coumarone, steroids, tri-terpenes, iosflavanoids, isovestitol, and sativan and betulinic acid, flavanoid and medicarpin. The plant mainly use for colic disorder, jaundice, small pox, catarrh, headache, epilepsy. Flower juice is mainly used for eye disease.

Hence, the current study was done to delineate pharmacognosy of the stem of plant Striga Orobanchioides Benth (Scrophulariaceae). MATERIALS AND METHODS Chemicals and instruments Potassium hydroxide, hydrochloric acid, Phloroglucinol, glycerin and all other chemicals used in the study were of analytical grade. Rotary microtome was used for taking sections.

Background: Feronia elephantum (Rutaceae), frequently named wood apple, is a preferable medicinal plant. In Ayurveda, its bark has been recommended for the treatment of diabetes. In addition, it is one of the active chemical constituent decursin, shown in recent research to have significant impacts on colon cancer, breast cancer, Alzheimer's disease, inflammation, and ulcerative colitis. Objective: The present study was carried out to investigate the traditional use of Feronia elephantum bark in streptozotocin-induced diabetes and lipid-lowering action in rats. Decursin has been isolated from the bark and tested for in vitro and in vivo biological activities. Methods: The Soxhlet extraction method obtained the ethanolic extract, and fractionation was done with column chromatography and TLC. The structure of isolated decursin has been confirmed by Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopy. Results: The decursin noticeably depletes increased blood glucose levels and positively affects altered lipid profile after administering a dose of 150 mg/kg orally compared with the oral hypoglycemic drug metformin. In molecular docking simulations, decursin exhibited excellent inhibition of α-amylase, dipeptidyl peptidase-IV, and moderate activity against α-glucosidase and glucokinase. Furthermore, the enzymes 3-hydroxy-3-methylglutaryl coenzyme A and Niemann-Pick C1-Like 1 are ideal targets to control hyperlipidemia and have shown moderate inhibition by decursin. Conclusion: From these results, it has been concluded that decursin can be a perfect candidate for further optimization as a lead molecule to treat diabetes and hyperlipidemia.