Additionsreaktion des Mischanhydrids (IV) mit der aus den Komponenten (I) und (II) erhältlichen Schiffbase (III) gibt die isomeren Lactame (Va) (3 z2‐Isomerengemisch) und (Vb) + (Vc); (Vb) wird dann wie angegeben in die Titelverbindung (IXa) übergeführt.
The 4‐(methylsulfonyl)azetidinone (I) is desulfonated with sodium boranate, detritylated with p‐toluenesulfonic acid monohydrate and then coupled with p‐nitrobenzaldehyde (III) to form the imine (IV).
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