In the present work, fluoride conversion coating was formed on AZ31 magnesium alloy at 40 °C and the conversion time was optimized. A smooth surface with pores were formed which was observed from SEM. The crystalline MgO and MgF2 formed on the surface were confirmed by EDAX and X‐ray diffraction (XRD). The investigation on corrosion behavior of the coating was performed using potentiodynamic polarization, potentiostatic polarization and dynamic electrochemical impedance studies (DEIS). The coating stability was studied at various potentials ranging from −1.78 to −1.09 V which depicts that the coating was stable for wide range of potentials as compared to the substrate. The in vitro biomineralization of the coating was analyzed by immersing in Earle's solution for 7 days and the formation of nanospherical carbonated apatite with fluorine and magnesium was revealed by SEM/EDAX and ATR‐IR spectroscopy. The osteointegration and proliferation of MG63 and MSC cells on the coating were examined using MTT assay.
The removal of tumors in the osseous
tissue leads to functional
disorders. To overcome this issue, biodegradable implants are used
to replace the damaged part of the system. In the study, samarium
oxide was coated on the anodic layer of AZ31 magnesium alloy. The
potentiodynamic polarization, electrochemical impedance, and localized
electrochemical impedance spectroscopy studies were carried out for
the samarium-coated magnesium alloy. The corrosion resistance of the
coating improved several folds than the bare alloy. The apatite formed
on the 3rd day of immersion in the simulated body fluid showed cuboid
and triangular structures, whereas on the 7th day, it exhibited a
sea sponge-like appearance. The coating exhibited inherent anticancer
and antibacterial properties. Our work suggests that the samarium
coating is expected to be a promising orthopedic implant for preventing
tumor relapse and metastasis.
Biogenic synthesis of silver nanoparticles (SS-Ag NPs) using the extract of Saccharum spontaneum (SS) via green chemistry route was investigated for their in-vitro cytotoxicity on osteoblast-like cells and bactericidal effect. Synthesized SS-Ag NPs were analyzed using TEM, FTIR, XRD and UV Vis spectroscopy techniques. The biomolecules present in S. spontaneum were responsible for the reduction and capping of silver nanoparticles. A heterogenous mixture of SS-Ag NPs which consists of triangle, hexagonal, spherical and rod-like structures was obtained. Furthermore, the synthesized SS-Ag NPs were tested for in a broad spectrum of antibacterial activity against E. coli, S. aureus, K. pneumonia and P. aeruginosa and it showed significant inhibitory effect. For the first time, the enhancement in the proliferation rate of MG63 cells with SS-Ag NPs is reported.
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