Dynamic electrochemical impedance study of fluoride conversion coating on AZ31 magnesium alloy to improve bio‐adaptability for orthopedic application

Abstract

In the present work, fluoride conversion coating was formed on AZ31 magnesium alloy at 40 °C and the conversion time was optimized. A smooth surface with pores were formed which was observed from SEM. The crystalline MgO and MgF2 formed on the surface were confirmed by EDAX and X‐ray diffraction (XRD). The investigation on corrosion behavior of the coating was performed using potentiodynamic polarization, potentiostatic polarization and dynamic electrochemical impedance studies (DEIS). The coating stability was studied at various potentials ranging from −1.78 to −1.09 V which depicts that the coating was stable for wide range of potentials as compared to the substrate. The in vitro biomineralization of the coating was analyzed by immersing in Earle's solution for 7 days and the formation of nanospherical carbonated apatite with fluorine and magnesium was revealed by SEM/EDAX and ATR‐IR spectroscopy. The osteointegration and proliferation of MG63 and MSC cells on the coating were examined using MTT assay.

In Vivo Corrosion Behavior of Biodegradable Magnesium Alloy by MAF Treatment

“…In this experiment, the processed AZ31 samples were processed at 190 V constant voltage mode. Figure 2 shows the rough coral-like surface morphology of the microarc fluoride treated magnesium alloy, similar to previous MAF coatings at high voltages [15,16,30]. Figure 5…”

Progress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation

“…Under chronic exposure, significant loss of dendrite and soma of neurons induced down-expressions and other behavioural deficits [ 6 , 100 ]. Fluoride Conversion Coatings (FCCs): Several authors [ [101] , [102] , [103] , [104] ] reported the development of FCCs on Mg alloys for biomedical implant applications. The coating procedure is typically performed by immersing Mg or Mg alloy substrates in 40%–48% hydrofluoric (HF) acid solution [ 69 , 105 ].…”

Facile synthesis of Silver nanoparticles with medicinal grass and its biological assessment

“…The percentage of hemolysis was calculated as, MTT assay was performed to determine the cytotoxic behavior of the SS-Ag NPs. 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) was added with the cells and incubated for 4 h. 1 mL of dimethyl sulphoxide (DMSO) was added to dissolve the formazan crystals and the optical density values were measured at 570 nm using ELISA reader (Bio-Rad 680, USA) [64]. The assay was performed in triplicate and the percentage of cell viability was calculated using the following formula.…”