Background:The methanolic extract of Sargassum ilicifolium (Pheophyceae) was used to evaluate its analgesic and anti-inflammatory activity in the present study.Materials and Methods:Analgesic activity was tested using Acetic acid writhing method and Eddy hot plate method in Male albino mice and Wister rats respectively at a dose level of 1, 10, 50, 100mg/kg p.o. At the same dose, its anti-inflammatory activity was also tested using Carrageenan induced rat paw edema method Result Acetic acid writhing test and Eddy's hot plate episodes were significantly and dose dependently reduced. Carrageenan (a standard inflammatory agent) induced paw edema in rats was significantly reduced after intraperitonal administration of methanolic extract.Results:showed dose dependant significant activity in comparison with standard and control.Conclusion:Methanolic extracts of the brown seaweeds Sargassum ilicifolium have potent analgesic and anti-inflammatory activity at moderate doses.

No abstract

The present paper reports a simple, accurate and precise spectroscopic technique for estimation of Lansoprazole by first order derivative technique in tablet dosage form. The spectroscopic method for estimation of Lansoprazole by first order derivative technique was carried out using methyl alcohol as solvent. The absorbance maximum was 275nm. Beers law observed in the range of 30 - 150μg/ml concentration. The recovery studies demonstrated the accuracy of the proposed procedure and the results were established as per ICH guidelines. The technique was used successfully for the estimation of Lansoprazole in bulk and tablet and pure dosage form.

No abstract

An easy, perfect, specific, and accurate process has been studied for the estimation of acarbose pure drug form, as well as, tablet dosage forms. Using methanol as a solvent, acarbose has absorbance maxima at 206 nm, and this drug shows a linear response according to Beer’s law in the concentration range of 24 to 40 μg/mL. The outcomes of the study were validated statistically, and recovery studies were satisfactory as per ICH guidelines. Thus, the projected method can be proficiently useful for the estimation of acarbose in regular analysis effort.