The effect of treatment with combined butylparaben and triclosan on male gonadal toxicity in weanling rats was investigated. All treated groups experienced atrophy in the ventral prostate and seminal vesicle, likewise significant depletion in the number and motility of sperm. Given individually or combined butylparaben and triclosan, significantly decreased testosterone, luteinizing hormone, and follicle-stimulating hormone levels. Individual treatment with tested compounds caused significant elevation in the E level, whereas combined treatment did not alter the E level. Testicular DNA damage was recorded in all treated groups. Moreover, the testicular malondialdehyde level was significantly elevated, along with a significant decrease in catalase enzyme activity in all treated groups. Superoxide dismutase enzyme activity was significantly decreased in the butylparaben-treated group, increased in the triclosan-treated group, and nonsignificantly changed the butylparaben-triclosan-treated group. The combined treatment produced an endocrine disturbance with a concomitant induction of testicular oxidative stress, which may represent a common mechanism of endocrine disruptor-mediated dysfunction.

No abstract

No abstract

Diabetes is the most common endocrine disorder contributing to high morbidity and mortality globally. Due to the side effects reported for anti-diabetic drugs, there is a rising interest in herbal medicine for diabetes mitigation. However, rare studies were performed to analyze the molecular effects of natural agents on diabetes. Therefore, this study is the first to assess the possible ameliorating effects of avocado and cinnamon extracts on streptozotocin (STZ)-induced disturbances in the gene expression of PDX1 and Ins1 in type-2 diabetic rats, in comparison to metformin. A total number of 50 male Albino rats were randomly divided into five groups; normal control, STZ-induced diabetic group (65 mg/kg b.w divided into three doses 5 days apart), three other STZ-

The barrier layer at a free surface of a PbI, crystal surrounded by a non-polar gas has been found to exhibit pronounced voltage rectification when passed by an alternating current of constant amplitude Io. The rectified voltage Us is found proportional to I:, and its temperature dependence at low temperatures is of the form 1/T. The rectification may be quenched by weakly absorbed light in a certain wavelengths range. The light-induced relaxation of U , has a half-life time t l / z = to exp u/kT where u is the activation energy.There is direct proportionality between Us and the ambient gas pressure P, but the pressure dependence of t i p is of the form P -W . Heat treatment of PbI, enhances, while iodine vapour suppresses Us and t 1 / 2 . Correlation of this behaviour with ion adsorption-desorp tion processes is pointed out. On avait trouv6 que la couche barrikre sup une surface libre d'un cristal PbI, entour6 par un gaz non-polair montre une rectification de voltage prononcbe lorsqu' elle est traversbe par une courant alternatif d'amplitude constante I,. Le voltage rectifib Us est proportionnel iL I:, e t son d6pendance de la temperature (basses temperatures) a la forme 1/T. La rectification peut atre eteinte par une lumiere faiblement absorbbe, comprise dans une bande des longeurs d'onde. La relhchement de U s produite optiquement, a un temps de demie-vie t1/2 = to exp ulkT, o h u est l'energie d'activation. I1 y a une proportionnalitb directe entre U s et la pression P de gaz ambiant, mais la dbpendance de tlp de pression a la forme P-1/2. Le traitement thbrmique de PbI, augmente U s et t 1 / 2 , tandis que la vapeur d'iode supprime tous les deux. La correlation de la conduite observbe avec des processus adsorption-desorption ionique est indiqube.

Abdelaziz was also the former Head of the Public Relations and Advertising Department and the former Dean of the Faculty of Mass Communication, Cairo University. He is also an expert of social marketing and media campaigns in Egypt and the Arab world and a member of the Board of Trustees of the Egyptian Radio and TV Union. Taking into consideration his wide experience in the media field, prof. Abdelaziz was appointed as the head of the Media Studies Sector Committee at the Supreme Council of Universities. Moreover, Prof. Abdelaziz is a renowned expert in public opinion measuring studies and political marketing. He is also the founder and owner of Ro2yaa advertising agency.

Abdelaziz was also the former Head of the Public Relations and Advertising Department and the former Dean of the Faculty of Mass Communication, Cairo University. He is also an expert of social marketing and media campaigns in Egypt and the Arab world and a member of the Board of Trustees of the Egyptian Radio and TV Union. Taking into consideration his wide experience in the media field, prof. Abdelaziz was appointed as the head of the Media Studies Sector Committee at the Supreme Council of Universities. Moreover, Prof. Abdelaziz is a renowned expert in public opinion measuring studies and political marketing. He is also the founder and owner of Ro2yaa advertising agency.

Some observations are reported on voltage rectification across a barrier layer at a free surface of a high-resistivity CdS crystal traversed by a low-frequency alternating current of small constant amplitude. The rectified voltage is found to depend sensitively on the nature of the ambient gas and to quench out completely in the presence of traces of vapours of alcohols. It is confirmed that chemisorbed oxygen is largely responsible for the surface charge in crystals surrounded by atmospheric air. In addition to chemical quenching of rectification, optical quenching due to photodesorption is observed at a critical wavelength (outside the fundamental absorption band) which is characteristic of the ambient gas. The temperature dependence of the rectified voltage in the range -20-80°c exhibits a sharp drop above room temperature which may be interpreted as due to a decrease of barrier resistance rather than to thermal desorption. At low temperatures the rectified voltage is inversely proportional to the absolute temperature, in accordance with theoretical prediction.