Objectives: To describe Chinese nursing home residents' knowledge of advance directive (AD) and end-oflife care preferences and to explore the predictors of their preference for AD. Design: Population-based cross-sectional survey. Settings: Nursing homes (n ¼ 31) in Wuhan, Mainland Southern China. Participants: Cognitively intact nursing home residents (n ¼ 467) older than 60 years. Measures: Face-to-face questionnaire interviews were used to collect information on demographics, chronic diseases, life-sustaining treatment, AD, and other end-of-life care preferences. Results: Most (95.3%) had never heard of AD, and fewer than one-third (31.5%) preferred to make an AD. More than half (52.5%) would receive life-sustaining treatment if they sustained a life-threatening condition. Fewer than one-half (43.3%) chose doctors as the surrogate decision maker about lifesustaining treatment, whereas most (78.8%) nominated their eldest son or daughter as their proxy. More than half (58.2%) wanted to live and die in their present nursing homes. The significant independent predictors of AD preference included having heard of AD before (odds ratio [OR] 9.323), having definite answers of receiving (OR 3.433) or rejecting (OR 2.530) life-sustaining treatment, and higher Cumulative Illness Rating Scale score (OR 1.098). Conclusions: Most nursing home residents did not know about AD, and nearly one-third showed positive attitudes toward it. AD should be promoted in mainland China. Education of residents, the proxy decision maker, and nursing home staff on AD is very important. Necessary policy support, legislation, or practice guidelines about AD should be made with flexibility to respect nursing home residents' rights in mainland China.With the aging of China's population, the demand for nursing home care is increasing.1 In Wuhan, a southern city in Hubei province, Mainland China, there are approximately 9.79 million people.

No abstract

No abstract

Mycoplasmas are a group of microbes that can cause human diseases. The mycoplasmal lipoprotein p37 promotes cancer metastasis, at least in part, by interacting with EGFR. In this study, we show that the p37 lipoprotein binds another member of the EGFR family, HER2, through the HER2 extracellular domain. The binding of p37-HER2 promotes phosphorylation of HER2 and activates the downstream signaling molecule Erk1/2. Because the HER2 signaling pathway contributes to breast tumor metastasis, our results imply that the mycoplasmal lipoprotein p37 may also be involved in breast cancer metastasis. This study contributes to our understanding of mycoplasmal lipoprotein p37 function and its potential involvement in tumorigenesis.

To explore the association between dental anxiety and oral health-related quality of life among Chinese pregnant women. A cross-sectional survey was conducted on a consecutive 502 pregnant women in the outpatient departments of Obstetrics and Gynecology from a local general hospital. The measures included a dental anxiety questionnaire to assess dental anxiety, the Chinese version of Oral Health Impact Profile to assess oral health-related quality of life, and a self-designed questionnaire to collect data on the socio-demographic and clinical characteristics. Of the participants, 26.7% suffered from dental anxiety. The overall OHIP-14 was 9.16 ± 7.19. Both bivariate and multivariate analysis found that higher dental anxiety was significantly associated with lower oral health-related quality of life (P < 0.001). The dental anxiety of pregnant women may be a significant indicator of their oral health-related quality of life.

Abstract-This study explored the effect of Health Quotient (HQ) management on maternal quality of life and the incidence of health problem during puerperium in Cox's Interaction Model of Client Health Behavior (IMCHB). A quasi-experimental posttest design with two groups was used. Totally 60 new mothers were conveniently selected and divided into observation group (n=30) and control group (n=30). According to one's HQ level, the observation group was provided with individualized reaching under the guidance of IMCHB, while the control group was provided with conventional teaching. At 42-days postpartum clinic, the incidence of maternal health problem and the quality of life were compared between the two groups. After intervention, the incidences of low back pain, constipation and other health problems in the observation group were significantly lower than those in the control group (P < 0.05), and the scores of all dimensions of quality of life in the observation group were significantly higher than those in the control group (P < 0.05). The results indicate that, compared with conventional teaching method, the teaching mode of HQ management based on IMCHB can effectively reduce the incidence of postpartum health problems and improve maternal quality of life.

Abstract.To explore the status of perceptions of general health and future risk, and their association among Chinese elderly patients with type 2 diabetes. A descriptive cross-sectional survey was used. Totally, 142 hospitalized patients aged 60 and over with type 2 diabetes were recruited from two local general hospitals. The data on their basic information, self-rated health, and risk perception for diabetes-related complications were collected by questionnaires and/or from medical records. Among the participants, 80.2% indicated that their general health was poor or fair, and only 2.1% reported very good health. Low perception of risk for diabetes complications was observed, which was incongruent with the physiologic indexes of risk. In multiple regression analysis, self-rated health had a small but significant impact on one's perceived future risk. A better self-rate general health status was associated with a lower level of risk perception. Accordingly, it is important to develop appropriate health education programs by addressing risk factors and risk status to heighten their perceived risk for diabetes complications in this group of people.