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Highlights (Up to four bullet points. The length of each highlight cannot exceed 85 characters, including spaces) ! Stress induces phase-separated TDP-43 NBs to alleviate cytotoxicity ! The two RRMs interact with different RNAs and act distinctly in the assembly of TDP-43 NBs ! LncRNA NEAT1 promotes TDP-43 LLPS and is upregulated in stressed neurons ! The ALS-causing D169G mutation is NB-defective and forms pTDP-43 cytoplasmic foci .

Fusarium stalk rot (FSR) caused by Fusarium graminearum (FG) significantly affects the productivity of maize grain crops. Application of agrochemicals to control the disease is harmful to environment. In this regard, use of biocontrol agent (BCA) is an alternative to agrochemicals. Although Trichoderma species are known as BCA, the selection of host-pathogen specific Trichoderma is essential for the successful field application. Hence, we screened a total of 100 Trichoderma isolates against FG, selected Trichoderma harzianum (CCTCC-RW0024) for greenhouse experiments and studied its effect on changes of maize rhizosphere microbiome and biocontrol of FSR. The strain CCTCC-RW0024 displayed high antagonistic activity (96.30%), disease reduction (86.66%), biocontrol-related enzyme and gene expression. The root colonization of the strain was confirmed by eGFP tagging and qRT-PCR analysis. Pyrosequencing revealed that exogenous inoculation of the strain in maize rhizosphere increased the plant growth promoting acidobacteria (18.4%), decreased 66% of FG, and also increased the plant growth. In addition, metabolites of this strain could interact with pathogenicity related transcriptional cofactor FgSWi6, thereby contributing to its inhibition. It is concluded that T. harzianum strain CCTCC-RW0024 is a potential BCA against FSR.

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The India‐Asia collision resulted in the Cenozoic framework of faults, ranges, and tectonic basins and the high topography of the northeastern Tibetan Plateau, but how and when these features formed remains poorly understood, leading to conflicting tectonic models. However, information on the tectonic evolution of these active orogenic belts is well preserved in synorogenic basin sediments. In this study, we carefully analyze the detrital apatite fission track ages of Cenozoic synorogenic sediments from the Jiuquan Basin to decipher the entire exhumation process of the adjacent Qilian Shan throughout the Cenozoic. Our data indicate that initially rapid Cenozoic exhumation occurred in the Qilian Shan during the late Paleocene‐early Eocene (~60–50 Ma), almost synchronous with the India‐Asia collision. The Qilian Shan subsequently experienced long‐lived exhumation that continued until at least the middle Miocene (~45–10 Ma). During this period of exhumation in the Qilian Shan, tectonic deformation occurred throughout the northeastern Tibetan Plateau. The early Cenozoic deformation in the northeastern Tibetan Plateau may have been caused by the transfer of tectonic stress from the distant India‐Asia collision boundary through the complex lithospheric environment of the Tibetan Plateau. The present tectonic configuration and topography of the Qilian Shan and the northeastern Tibetan Plateau likely became established since the middle Miocene and after the long‐lived deformation began in the early Cenozoic.

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