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Article InfoIntroduction: Nasopharyngeal carcinoma is common in China and Southeast Asia, including Indonesia. The cases are often diagnosed in an advanced stage with a poor prognosis. Objective: The purpose of this study was to determine the incidence of anemia in nasopharyngeal carcinoma patients in the ENT-HNS Department West Nusa Tenggara Hospital. Methods: the methods of this research are a descriptive study that used data from the medical record of West Nusa Tenggara Hospital. The data were obtained between April 2017 to September 2017. Result: During the study periods, we obtained 32 cases. 75% of patients were male and 25% female, with ratio 3:1. According to the age, patients were distributed from 28 to 69 years old with peak incidence at 41-60 years old. Most patients were stage IV (68.75%). There was 87.51% patient with anemia in this research. However,the highest number was found mild anemia 59.38% and the most types of anemia were hypochromic microcytic. Discussion: In this study, patients with advanced stages were 93.75%, consist of stage IV (68.75%) and stage III (25%), followed by stage II 6.25%, while stage I was not found. This shows that patients usually come at an advanced stage because of the low awareness of the NPC in medical personnel in Indonesia. Conclusion: The incidence of anemia in a patient with nasopharyngeal cancer in West Nusa Tenggara Hospital is 87.51%. Most of them were mild grade and hypochromic microcytic type.

Background: Noise pollution or noise is an unwanted sound which is disturbing to human beings.However small or soft the sound, if it is undesirable it is considered as noise. Noise induced hearingloss is a sensorineural hearing loss that is commonly encountered second to presbycusis. Purpose: Toknow the effect of traffic noise exposure on hearing impairment to the employees of the Parking DistrictCompany of the Denpasar city and to improve diagnostic detection on hearing impairment caused bynoise. Method: A cross sectional study was conducted at the Parking District Company office. Thepopulations of this study were the employees of the Parking District Company. Samples of this study were the employees who were exposed to traffic noise and control samples were an employee who was unexposed. Samples were selected by simple random sampling. Results: From 40 parking attendants,27 persons (67.5%) aged above 35 years old. The parking attendants who had been working for ten to fifteen years were 36 persons (90%) and no history using ear protection when working. Seven persons(17.5%) had referred DPOAE upon examination with increase hearing threshold on audiogram result.In this study the parking attendants who had hearing deficit induced by noise were 7 persons (17.5%)and only one person (2.5%) in control group. There was a statistically significant effect of traffic noiseto hearing function deficit (p<0.05). Conclusion: Traffic noise has effect in hearing function deficit onthe parking attendants.ORLI Vol. 40 No. 2 Tahun 2010Key words: NIHL, parking attendant, audiometry, DPOAE.

Introduction: Nasopharyngeal carcinoma is the most common malignant tumor in the ENT-HNS were the highest of all malignant tumors of the head and neck. Malnutrition and cachexia is a common problem in cancer patients and impact on quality of life and survival. Anemia is a major problem in patients with nasopharyngeal cancer receiving chemotherapy or radiotherapy. Objective: Determine the relationship of nasopharyngeal carcinoma stage with anemia and nutritional status. Material and methods: This study used cross sectional analytic method. Data were obtained from medical records of patients with nasopharyngeal carcinoma who were treated in province hospital West Nusa Tenggara period January 2018 to December 2018. Data collected include the identity, diagnosis, hemoglobin value, weight and height. Having analyzed the data collected are looking for is there a relationship between stage nasopharyngeal carcinoma with anemia and nutritional status. Results: In this study, Shapiro-Wilk normality test. Anova is then performed to analyze the relationship stage nasopharyngeal carcinoma with anemia status obtained 95% CI, p value 0.847, there is no difference between stage nasopharyngeal carcinoma with anemia. Kruskal Wallis test to analyze the relationship with BMI (body mass index) with stage nasopharyngeal carcinoma obtained 95% CI, p value 0.565. There is no difference in BMI with stage nasopharyngeal carcinoma. Conclusion: There is a tendency to lower Hb in patients with nasopharyngeal cancer further stage although there is no significant difference between each stage. The same thing was found in BMI, BMI decreased tendency in patients with advanced nasopharyngeal cancer although there was no statistically significant difference.

BACKGROUND:Purple sweet potato tuber ethanol extract (PSPTEE) has been known to have benefits in various disease, including to prevent nasopharyngeal carcinoma (NPC). However, there has been no research on PSPTEE in preventing the proliferation of nasopharyngeal mucosal epithelial cells induced by formaldehyde through the oxidative stress mechanisms and inflammatory process. Studies have proven the effect of PSP on various cancer cells, but the carcinogenesis process of the nasopharyngeal mucosal epithelium is still limited. Hence, this study aimed to demonstrate the mechanism for preventing histopathology changes with PSPTEE due to formaldehyde exposure.METHODS: Thirty-two formaldehyde-induced Wistar rats were treated with or without 1g/kgBW/day PSPTEE for 16 weeks. Malondialdehyde (MDA) level were examined with spectrophotometry method, while tumor necrosis factor (TNF)-α and p53 with enzyme linked immunosorbent assay (ELISA) method. The histopathology appearance of the nasopharyngeal epithelium was observed with hematoxylin-eosin (HE) staining.RESULTS: MDA and TNF-α levels in control and treatment group were 22.89±2.84 μM; 9.83±0.89 μM and 84.18±11.58 ng/L; 73.92±10.59 ng/L, respectively, and they showed significant difference. Meanwhile, the level of p53 showed no significant difference. Histopathology appearance showed a significant difference. Path analysis for MDA, TNF-α and p53 levels contributed 28.7% to histopathology appearance. MDA have an effect on significant direct effect on TNF-α. TNF-α has a significant direct effect to histopathological appearance. Indirect influence MDA on histopatological appearance were smaller than the direct effect. TNF-α has the greatest influence on histopatological appearance.CONCLUSION: Formaldehyde induces the histopathology appearance in nasopharyngeal epithelium. This study also demonstrates the mechanism to prevent the nasopharynx epithelial histopathology appearance by administration of PSPTEE.KEYWORDS: PSP, MDA, TNF-α, p53, nasopharynx epithelial

ABSTRAKPenelitian ini bertujuan untuk : (1) mendeskripsikan serangkaian tradisi megibung mulai dari tahap persiapan, pengolahan hidangan, penyajian hidangan dan pelaksanaan megibung Di Desa Besakih, (2) memperkenalkan tradisi megibung di Desa Besakih melalui youtube. Jenis penelitian ini adalah penelitian deskriptif kualitatif. Teknik pengumpulan data menggunakan metode observasi,  wawancara, dan  dokumentasi. Instrumen penelitian mengunakan lembar observasi dan pedoman wawancara. Analisis data menggunakan teknik analisis deskriptif kualitatif. Hasil penelitian ini menunjukkan: (1) Tradisi megibung di Desa Besakih terdiri dari tahap persiapan, pengolahan hidangan, penyajian hidangan dan pelaksanaan megibung yang dilaksanakan dengan asas kekeluargaan dan gotong royong. Tahap persiapan meliputi persiapan bahan dan alat. Tahap pengolahan merupakan proses mengolah bahan makanan menjadi hidangan megibung. Hidangan yang disajikan terdiri dari nasi, olahan lawar yang meliputi lawar gecok, anyang, lawar belimbing, lawar jeruk dan lawar nangka, sate gede serta kuah trengtengan. Tahap penyajian terdiri dari gibungan yang diletakkan ditengah sele serta olahan lawar diletakkan disisi kanan dan kiri gibungan. Tahap pelaksanaan megibung, peserta duduk melingkar dengan etika tangan kanan mengadap ke gibungan dan berkhirnya acara setelah semua makanan selesai dinikmati. (2) Pengenalan tradisi megibung di Desa Besakih melaui youtube yaitu mendokumentasikan serangkaian acara megibung dengan menampilkan realita yang ada. Penggunaan teknologi menjadi fokus utama media pengenalan yaitu youtube popular  youtube untuk mengunggah video via online, sehingga dapat memberikan dampak edukasi dan pengetahuan bagi masyarakat mengenai tradisi megibung yang perlu dijaga dan dilestarikan.