Incidence and characteristics of anemia among patients with nasopharyngeal carcinoma in Lombok, Indonesia

Kadriyan, Hamsu; Sulaksana, Mochammad Alfian; Lestarini, Ima Arum; Susilawati, Ni Ketut; Punagi, Abdul Qadar; Pieter, Nova Audry L.; Gaffar, Masyita

doi:10.1063/1.5141329

Cited by 8 publications

(16 citation statements)

References 10 publications

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“…Similar with the previous reports, in this study, NPC patients was frequently found in fourth decades of life, men was more affected than women and predominantly in advanced stage [1,11]. The finding of anemia in this study also equal to the other reports (70% vs 80%) [11].…”

Section: Discussionsupporting

confidence: 91%

“…However, according to our study, there was no significant relationship between stage of NPC with anemia severity and malnutrition severity. Kadriyan et al, (2019) found the pattern of anemia was following the severity of the NPC stage, although its not significantly different between the stage [11]. A similar result was reported by Trijayanti et al,, (2016) who found there was no significant correlation between the stage and nutritional status, however the undernutrition was found predominantly in the advance stage cancer [16].…”

Section: Discussionsupporting

confidence: 69%

“…Anemia is a major problem in patients with nasopharyngeal cancer. In Indonesia found more than 80% of patients with NPC were suffered from anemia [11]. Anemia is a hemoglobin level in red blood cells less than normal.…”

Section: Introductionmentioning

confidence: 99%

“…The more advanced the cancer, the treatment would be more complex and the prognosis would be worst. Unfortunately, nutritional status and anemia were found more frequent in advanced stage [11,12]. Several question arise regarding those facts, including the relationship between the stage of NPC with anemia and nutritional status.…”

Section: Introductionmentioning

confidence: 99%

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The Relationship Between the Stage of Nasopharyngeal Carcinoma With Anemia and Nutritional Status in West Nusa Tenggara General Hospital

Susilawati¹,

Kadriyan²,

Sutirtayasa

2020

IJNPC

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Introduction: Nasopharyngeal carcinoma is the most common malignant tumor in the ENT-HNS were the highest of all malignant tumors of the head and neck. Malnutrition and cachexia is a common problem in cancer patients and impact on quality of life and survival. Anemia is a major problem in patients with nasopharyngeal cancer receiving chemotherapy or radiotherapy. Objective: Determine the relationship of nasopharyngeal carcinoma stage with anemia and nutritional status. Material and methods: This study used cross sectional analytic method. Data were obtained from medical records of patients with nasopharyngeal carcinoma who were treated in province hospital West Nusa Tenggara period January 2018 to December 2018. Data collected include the identity, diagnosis, hemoglobin value, weight and height. Having analyzed the data collected are looking for is there a relationship between stage nasopharyngeal carcinoma with anemia and nutritional status. Results: In this study, Shapiro-Wilk normality test. Anova is then performed to analyze the relationship stage nasopharyngeal carcinoma with anemia status obtained 95% CI, p value 0.847, there is no difference between stage nasopharyngeal carcinoma with anemia. Kruskal Wallis test to analyze the relationship with BMI (body mass index) with stage nasopharyngeal carcinoma obtained 95% CI, p value 0.565. There is no difference in BMI with stage nasopharyngeal carcinoma. Conclusion: There is a tendency to lower Hb in patients with nasopharyngeal cancer further stage although there is no significant difference between each stage. The same thing was found in BMI, BMI decreased tendency in patients with advanced nasopharyngeal cancer although there was no statistically significant difference.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Relationship Between the Stage of Nasopharyngeal Carcinoma With Anemia and Nutritional Status in West Nusa Tenggara General Hospital

Susilawati¹,

Kadriyan²,

Sutirtayasa

2020

IJNPC

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“…The more advanced the cancer, the more complex the treatment and the worse the prognosis. Unfortunately, nutritional status is found more frequently in advanced stages [7], [8]. Several questions related to these facts, including the relationship between NPC stage and anemia and nutritional status.…”

Section: Introductionmentioning

confidence: 99%

Nutritional Status of Patients with Nasopharyngeal Carcinoma

Dewi

Fakhrizal

Boesoirie

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Nasopharyngeal carcinoma (NPC) is the most common malignant tumor found in the otorhinolaryngology department of the head and neck. On the other hand, malnutrition is common problems among patients with cancer. AIM: The objective of the study was to determine the relationship between NPC stage and nutritional status. METHODS: Data were obtained retrospectively through medical records of NPC patients at Hasan Sadikin General Hospital Bandung and Santosa Hospital Bandung Kopo who were examined in the first examination between 2016 and 2020. Data collection included age, gender, NPC stage, and body mass index (BMI) of all patients. To analyze the association among variables, Mann–Whitney, Chi-square test with alternative Kolmogorov–Smirnov test and Fisher’s exact for categorical data, and multivariate analysis with binary logistic regression were performed. RESULTS: Patients who were included in this study found 554 people, mostly malnourished. There was a significant difference between the NPC stage and the level of malnutrition with p = 0.0001, but there was no significant difference between the NPC stage and age (p = 0.353), the NPC stage and gender (p = 0.074), BMI and age only (p = 0.194), early stage only (p =0.464), and late stage only (p = 0.368); BMI and gender in early and late stage (p = 0.411), early stage only (p = 0.583), and late stage only (p = 0.731). CONCLUSION: At an advanced stage of NPC, the BMI value will be lower.

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The trend of hemoglobin levels in nasopharyngeal cancer patients treated with chemotherapy in low human development index region in Indonesia

Lestarini

Kadriyan

Sulaksana

et al. 2021

IOP Conf. Ser.: Earth Environ. Sci.

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Nasopharyngeal cancer (NPC) is a malignant tumor in the epithelial cell of the nasopharynx. Globally, the incidence was around 80,000 new cases annually or it composed 0.7% of cancer cases in the world. In locally advanced cases, chemotherapy and radiotherapy is a treatment of choice for this cancer. Chemotherapy could be given before the radiotherapy, or simultaneous, or after the radiotherapy. Chemotherapy can affect the hemoglobin levels by inducing a suppressive effect on bone marrow and a toxic effect on erythrocytes. Thus, this study aimed to explore the trend of hemoglobin levels in every cycle of chemotherapy in patients with NPC. This study is a retrospective study with secondary data collection of patients with NPC who received chemotherapy at the West Nusa Tenggara, one of the regions with low human development index (HDI) in Indonesia, during the period 2017-2019. The data obtained were analyzed descriptively and repeated measurement ANOVA test to explore the difference of hemoglobin levels during every cycle of chemotherapy. The results showed a trend of decreasing mean hemoglobin levels in six series of chemotherapy, with p-value = 0.06 on repeated measurement test. There was a trend of decreasing mean haemoglobin levels in patients with nasopharyngeal cancer who received chemotherapy in low HDI region in Indonesia.

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Incidence and characteristics of anemia among patients with nasopharyngeal carcinoma in Lombok, Indonesia

Cited by 8 publications

References 10 publications

The Relationship Between the Stage of Nasopharyngeal Carcinoma With Anemia and Nutritional Status in West Nusa Tenggara General Hospital

The Relationship Between the Stage of Nasopharyngeal Carcinoma With Anemia and Nutritional Status in West Nusa Tenggara General Hospital

Nutritional Status of Patients with Nasopharyngeal Carcinoma

The trend of hemoglobin levels in nasopharyngeal cancer patients treated with chemotherapy in low human development index region in Indonesia

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