The present paper is a review on hydrochlorothiazide, a diuretic frequently used in therapeutics, also underlining several particularities observed in time and correlated with the results in the literature in what concerns the phototoxic action of this diuretic on skin.

This paper aimed at the preparation and characterisation of an extractive solution of Kombucha. We have applied the method of water extraction of a species of yeast, Kombucha, grown and proliferated in the pharmaceutical technology laboratory of the Faculty of Pharmacy at Dunarea de Jos University of Galati. Samples of various sugar concentrations have been prepared, as well as samples subject to concentration, thus obtaining extracts of up to 80% concentration. The extract obtained was analysed chemically and microbiologically. The main elements highlighted in the composition of the extractive solution were: iron, zinc, magnesium, calcium and potassium. The antimicrobial activity in strains: Gram-positive: Staphylococcus aureus, Gram-negative: Pseudomonas aeruginosa, Escherichia Coli, fungi: Candida albicans.

The present paper aims at formulating, preparing, following the antibacterial activity of pharmaceutical forms with oral cavity applicability. Two pharmaceutical forms were prepared, a tincture and a toothpaste based on basil and propolis, being subsequently compared to the mix of basil and propolis tinctures that are commercially available; each pharmaceutical form was analyzed organoleptically and microbiologically. As a result of the measurements the conclusion was drawn that the tinctures prepared, the propolis tincture and the basil tincture show a strong sensitivity Staphylococcus aureus, Pseudomonas aeruginosa; and Enterococcus hormaechei.Candida albicans reacted more strongly to the propolis tincture, and less to the basil tincture. The scientific novelty of the paper consists in the formulation and determination of the antimicrobial activity of the toothpaste prepared in the laboratory of the Pharmacy Faculty of Galati. The results obtained were favorable on microorganisms acting on the oral cavity, i.e. gram positive germs, gram negative germs and fungi. Keyworlds:basil(Ocimum basilicum)propolis, lemon basil, tincture

The present paper aims at obtaining two pharmaceutical formulas based on two active principles extracted from two plants well-known for their contents of capsaicin and piperine, respectively, Capsicum Annuum and Piper Nigrum. After the extraction of the active principles, we pursued their identification using chromatographic and spectrophotometric methods. Subsequently, we produced two pharmaceutical formulas, an ointment and a cream, in view of using them in rheumatic diseases as anti-inflammatory medicine.

The present paper has as main objective the determination of the antimicrobial and antifungal activity of some pharmaceutical forms obtained in the laboratory of pharmaceutical technology of the Faculty of Pharmacy of the University "Lower Danube of Galati". We used semi-solid pharmaceutical forms with different concentrations of soft extract of Chelidonium majus L, 50%, 25% and 10% in two ointment bases, simple ointment and base III I performed the antimicrobial activity for all four ointments, compared to extract 1: 3.75 in hydroalcoholic solution (ethyl alcohol / water 35/65 by mass) from aerial parts of Chelidonium majus and alcohol 70 °. hydroalcoholic solution was obtained by cold preparation from the aerial parts of the plant Chelidonium majus. We determined the antimicrobial activity by the diffusimetric method (Kirby-Bauer) and the dilution method. The 50% concentration ointment (UNG A) shows activity on some Gram-negative and Gram-positive bacteria and not on the fungus Candida albicans.