Pharmaceutical Forms with Basil and Propolis to the Benefit of the Oral Cavity. Formulation, preparation and microbiological analysis

Abstract

The present paper aims at formulating, preparing, following the antibacterial activity of pharmaceutical forms with oral cavity applicability. Two pharmaceutical forms were prepared, a tincture and a toothpaste based on basil and propolis, being subsequently compared to the mix of basil and propolis tinctures that are commercially available; each pharmaceutical form was analyzed organoleptically and microbiologically. As a result of the measurements the conclusion was drawn that the tinctures prepared, the propolis tincture and the basil tincture show a strong sensitivity Staphylococcus aureus, Pseudomonas aeruginosa; and Enterococcus hormaechei.Candida albicans reacted more strongly to the propolis tincture, and less to the basil tincture. The scientific novelty of the paper consists in the formulation and determination of the antimicrobial activity of the toothpaste prepared in the laboratory of the Pharmacy Faculty of Galati. The results obtained were favorable on microorganisms acting on the oral cavity, i.e. gram positive germs, gram negative germs and fungi. Keyworlds:basil(Ocimum basilicum)propolis, lemon basil, tincture

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