Formulation, Preparation, Physico-chimical Analysis, Microbiological Peculiarities and Therapeutic Challenges of Extractive Solution of Kombucha

Abstract

This paper aimed at the preparation and characterisation of an extractive solution of Kombucha. We have applied the method of water extraction of a species of yeast, Kombucha, grown and proliferated in the pharmaceutical technology laboratory of the Faculty of Pharmacy at Dunarea de Jos University of Galati. Samples of various sugar concentrations have been prepared, as well as samples subject to concentration, thus obtaining extracts of up to 80% concentration. The extract obtained was analysed chemically and microbiologically. The main elements highlighted in the composition of the extractive solution were: iron, zinc, magnesium, calcium and potassium. The antimicrobial activity in strains: Gram-positive: Staphylococcus aureus, Gram-negative: Pseudomonas aeruginosa, Escherichia Coli, fungi: Candida albicans.

Formulation and Preparation of Pharmaceuticals with Anti-rheumatic Effect Using the Active Principles of Capsicum Annuum and Piper Nigrum

“…Another promising indication is related to the usage of Piper Nigrum extract in the treatment of vitiligo, a cutaneous disease which causes color losses, occurring either by itself or associated with other autoimmune diseases, where the requirement of immunosuppressing, anti-inflammatory treatment could be complemented with natural extracts [36][37][38]. Experimentally, in the future, the natural extracts, either by themselves or combined, acting synergistically, could become useful in the prophylaxis of areas described as locus minoris resistentiae, or in the Wolf isomorphic phenomenon, which entails the occurrence of another dermatosis, different from the initial one, at the spot of cutaneous healing, a phenomenon which can also be understood as Koebner phenomenon type 5 [39][40][41]. Another possible domain can be represented by its use for ameliorating zoster or post-zoster pains, where capsaicin has a clearly quantified role owing to its capacity of inhibiting the P substance involved in the mechanism of zoster pain or that of other neuropathic pains or paresthesia.…”

Nutraceutical Properties of Apples and Derived Products (Pomace, Seeds, Peels)

“…It is useful, under specific circumstances, that new substances -perhaps plant derived products of limited adverse reaction potential -and non-aggressive alternative treatments to be investigated and used [18,37,46,56] for the prevention and management of chronic diseases. is well known today to use pharmaceuticals with retarding effect in the treatment of various diseases.…”

Undesirable Effects of Some Topical Antiseptics Chemical, pharmacological and dermatological aspects

“…Plant extracts with limited side effects potential should be used in selected cases, especially in Locus minorisresistentiae cutaneous areas [86][87][88][89]. Maybe a consensus on appropriate antiseptic solutions in dermatology would minimize possible medicolegal actions and our patients'suffering and risks.…”