A 52-year-old womanwith a history of a hearing disturbance since age 20 experienced visual hallucinations and convulsions, followed by right hemiparesis and aphasia. On the basis ofa muscle biopsy and mitochondrial DNAanalysis, she was diagnosed as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS).This case is unique in that the strokelike episodes occurred 30 years after disease onset. (Internal Medicine 35: 991-995, 1996)
There have been few case reports of pure anomic aphasia and the underlying mechanism remains to be clarified. Wereport a patient in whom pure anomic aphasia was caused by subcortical hemorrhage in the left temporo-parieto-occipital lobe. Based on magnetic resonance images and cerebral blood flow imaging, the structural lesion underlying the pure anomic aphasia was thought to be located at the left temporo-occipital junction. (Internal Medicine 38: 293-295, 1999)
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