This research is aimed at determining the effect of transformational leadership, organizational environment and work discipline on the performance of private universities employees in Bima. The analysis is also to determine dominant variable affecting the performance of employees performance. This research is causal associative. The population is the employees of all universities in Bima from which 69 respondent were selected. The data were collected through questionnaires. The test is conducted with validity and reliability test. The data then were analyzed with multiple linear regression along with determination test (R2) t-test (partial), standardized coefficients beta. The research showed that (1). there is significant effect partially of transformational leadership, organizational environment and work discipline on the performance of employees, (2) work discipline is the most dominant affecting variable on the employees performance.Keywords: transformational leadership, organizational environment, work discipline,

Social media is experiencing rapid development until now. Social media makes it easy for humans to be able to connect with one another. One of the social media that is widely used is Twitter. The ease of use makes social media widely used among the public, including state officials. State officials use Twitter to convey policies, opinions and interact with the public. By conducting a topic analysis of tweets shared by state officials, we can find out the relevant topics discussed by state officials. We can find out the focus of attention of state officials through topic modeling. Latent Dirichlet Allocation (LDA) is a topic modeling method that finds certain patterns in documents and produces several different topics. Tweets from the @jokowi account are collected using a scraping technique. The results of the tweet collection are then preprocessed for further analysis using the Latent Dirichlet Allocation (LDA) method. The results of the analysis model are evaluated using perplexity calculations and coherence scores. The evaluation of the model resulted in a perplexity value of -8.069 and a coherence score of 0.375 for a total of 7. This shows that the model used is good for analyzing and finding topics in tweets of state officials.

Virus Corona pertama kali terjadi di negara China pada Desember 2019 lalu, dan dengan cepat menyebar ke lebih dari 121 negara di dunia termasuk Indonesia. Kasus pertama virus corona di Indonesia terjadi pada awal Maret 2020 di kota Depok, Jawa Barat. Dengan terus meningkatnya jumlah kasus virus corona di Indonesia, pemerintah di Indonesia baik kota atau kabupaten hingga provinsi dan nasional memfasilitasi website informasi resmi terkait COVID-19 untuk memudahkan masyarakat dalam memantau penyebaran virus corona, Pemerintah Provinsi Jawa Barat merilis Aplikasi PIKOBAR (Pusat Informasi dan Koordinasi COVID-19) merupakan aplikasi resmi milik pemerintah provinsi Jawa Barat. Untuk mengetahui apakah aplikasi PIKOBAR merupakan bentuk kesigapan pemerintah provinsi Jawa Barat dalam memberikan informasi mengenai COVID-19 yang terverifikasi, transparan, akurat dan menghindari adanya hoax maka perlu dilakukannya analisis kesuksesan aplikasi dalam studi ini peneliti menggunakan metode Delone and McLean dengan hasil 57,1%.

This study aims to determine the extent of the influence of coordination on employee work effectiveness at the Regional Secretariat of Kendari City. By using questionnaire data collection techniques, documentation and interviews with informants who are considered potential to provide information about the coordination system and work effectiveness at the Kendari City Regional Secretariat.Then to test the hypothesis, statistical analysis techniques are used through simple linear regression, which is to find out the relationship between the independent variables (X), namely coordination and non-independent variables (Y), namely the effectiveness of employees in Kendari City. Testing the hypothesis is used version 22 of the Statistics Package for Social Science (SPSS) program. The results of this study indicate that coordination has a significant influence on the effectiveness of Employee Work in the Regional Secretariat of Kendari City. The results of testing the Spearman-Brown Correlation coefficient indicate that coordination has a relatively large contribution to work effectively in the Regional Secretariat of Kendari City. This means that the better the coordination is carried out, the higher the work effectiveness of employees. In this study, it was also found that the implementation of the main tasks and functions of the ten sections and twenty-nine sub-sections had not been implemented properly.

Background: Ovarian cancer is one of the leading cancers in women. Seventy percent were founded in the advanced stage, with a 5-year survival rate of only 46%. The current treatment modality is cytoreduction with platinum-based adjuvant chemotherapy as the first line. The effectiveness of chemotherapy is only 60% in the advanced stage, later developing into recurrent. Therefore, additional types of therapy are required based on agents that work specifically in cancer cells and synergize with current standard treatments. This study aimed to know the anti-proliferation effect and apoptosis effect of combination cisplatin with nanocurcumin on SKOV3 cells. Methods: This experimental study was conducted in vitro using the biological cell line SKOV3 to determine the anti-proliferation effect (expression Ki67) and the apoptosis effect (caspase 3 and 8) of combination cisplatin with combination with cisplatin nanocurcumin on the cell. The data were analyzed with unpaired T when regular distribution / Mann Whitney test when the distribution is abnormal and using Graph Pad Prism. Results: Based on this result, 50cc of nanocurcumin is 67 μm, and 50cc of cisplatin is 54 μm, using the MTT Assay method. The viability of the cells in this study decreased according to the dose-dependent, whereas the combined dose of 134 μm nanocurcumin with 108 μm cisplatin found the lowest life cell, 24.3% (p <0.001). Ki67 expression was low in the SKOV3 cells post-exposure to cisplatin, but increased post-exposure to nanocurcumin, suspected nanocurcumin at certain doses of pro-oxidant properties that triggered proliferation. Caspase 3 and 8 cannot be detected in this cell by the ELISA method. Conclusions: Nanocurcumin has a potential effect on chemosensitive cells. However, our study shows no healing effect in chemoresistance cells, particularly SKOV3.

Computer technology is neutral information technology without any subjectivities and biases. The advantages of computer technology can help to minimize intervention and subjectivity in the interpretation of the Quran. The problem of subjectivity in interpretation of the Quran is a long discussion. However, Interpretation of Quran has interrelated each other called tafsir al-Quran bil Quran method. This article proposes objective methodology and design of machine learning of Tafsir al-Quran using the advances in data science technology. Using the latest artificial intelligence technology that is Machine Learning and Natural Language Processing (NLP). Furthermore, this proposal proves the novelty of the role of technology in the preparation of religious material in millennial life from a secondary role to a primary role.

Permasalahan yang diteliti berkaitan dengan apakah ada pengaruh kepemimpinan, motivasi, komunikasi, disiplin kerja dan kepemimpinan terhadap kinerja pegawai. Adapun tujuan dari penelitian ini yaitu untuk mengetahui pengaruh kepemimpinan, motivasi, komunikasi, disiplin kerja dan kepemimpinan baik secara parsial maupun simultan terhadap kinerja pegawai. Penelitian inidilakukan pada Badan Pengelolaan Pajak Dan Retribusi Daerah Kabupaten Empat Lawang. Penelitian ini merupakan penelitian kuantitaif yang menggunakan regresi. Data dikelola dengan menggunakan SPSS. Adapun sample dalam penelitian ini berjumlah 40 responden. Berdasarkan uji secara parsial variable kepemimpinan, motivasi kerja, dan disiplin kerja berpengaruh secara parsial terhadap kinerja. Namun variable komunikasi menunjukkan hasil tidak signifikan. Hasil uji simultan menunjukkan bahwa semua variable berpengaruh signifikan terhadap Kinerja pegawai secara simultan. Berdasarkan hasil temuan penelitian maka kepemimpinan hendaknya memberikan teladan kepada pegawai, memberikan motivasi supaya pegawai tidak amals, selalu menjaga komunikasi dan memberikan sanksi terhadap pelanggaran disiplin kerja.

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