Introduction: Ovarian tumors represent about 30% of all cancers of the female genital system and 4% of all cancers in women. Indian trend analysis reveal a steady increase in the age-standardized incidence rate of ovarian cancer over past years, comprising up to 8.7% of cancers in different parts of the country. Aim and objective: To study the morphological pattern of benign and malignant ovarian neoplasm in various age presenting at our center over a period of 5-years. Material and methods: The present study was conducted retrospectively in the department of Pathology, BPS, GMC, Khanpur Kalan, Sonipat. Data was collected after reviewing cases from 2012 to 2016 (5years). All cases of ovarian neoplasm both primary (benign and malignant) and metastatic were included in the study. Results: Of the total 152 ovarian specimens that presented during the study period, 119 were benign, 5 were borderline tumors and 28 malignant. Most of the benign tumors occurred between 20-40 years of age, while malignant tumors presented commonly after 50 years of age. Out of these only 24 cases had bilateral ovarian neoplasm. Surface epithelial tumors were the most common type followed by germ cell tumors. Conclusion: Benign ovarian tumors were more common than malignant ones across all age groups. On morphological grounds, tumors originating from surface epithelium were the most common variant.
International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.
Introduction: Sepsis in elderly patients is a critical clinical issue due to high rates of morbidity and mortality. The modern age cell counters precisely measure volume, size and internal structure of the cell thereby assessing increase in volume and cytoplasmic granularity of leukocytes as seen in cases of sepsis. The present study was done to evaluate the use of Volume Conductivity Scatter (VCS) parameters as early indicators of sepsis in elderly patients and to overcome the shortcomings of blood culture by using a more precise VCS technology to assess morphologic changes in cell populations in sepsis. Material and Method: The study included 51 patients above the age of 50 years which were divided into 2 groups Group 1, patients with localised infection (n= 39) and Group 2 with systemic infection (n=12). Group 3 included 30 controls without any signs of infection and with total leucocyte count and differential counts within normal limits. Coulter LH 750 cellular analysis system was used. Result: Significant increase in both mean neutrophil volume (MNV) and mean monocyte volume (MMV) was reported among the patients with sepsis as compared to localized infections or control. With a cut off of 145 and 170 for MNV and MMV respectively, a sensitivity of 96% and 91.4% was obtained in predicting sepsis. Conclusion: Both MNV and MMV have the potential to be used as early indicators of acute bacterial infections.
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