No abstract

Oral antioxidants in the form of a combination of multivitamins and minerals (amino acid chelated) did not improve oocyte quality and pregnancy rates in women with unexplained infertility undergoing IVF/ICSI treatment.

CRD42016041301.

There was a significantly longer duration of both first and second stages of labor with higher rates of CS and maternal and fetal complications in women with OSA <126.

Routine premarital counseling and testing by reproductive health, gynecology, and andrology specialists need to be enforced. Mass media is an essential source of knowledge about HIV and reproductive health. Premarital, reproductive health, and HIV education programs need to be improved.

The measurement of both salivary progesterone and cervical length are good predictors for development of PTB.

Most surgical wound complications were reduced if skin closure with continuous subcuticular sutures is replaced with interrupted one.

Objective Evaluation of cell-free DNA (cf-DNA) as a noninvasive tool to discriminate between malignant and benign ovarian growth.Patients and methods DNA was extracted from the plasma of 50 women with ovarian lesion. A total of 20 women with pathologically proven malignancy and 30 women with benign ovarian lesions were included. Quantification of cf-DNA was performed using real-time PCR. cf-DNA was correlated with the histopathology. ResultsThe preoperative plasma cf-DNA level was statistically significantly higher (P < 0.0001) in the malignant group (3.6 ± 1.7 ng/ll) compared with the benign group (0.71 ± 0.69 ng/ml) with 5.04-fold higher in the malignant group than in the benign counterpart. The mean level of cf-DNA in women with benign ovarian lesion (0.71 ± 0.69 ng/ml) did not reach statistically significant difference (P = 0.2) when compared with the mean level among women having endometriotic cysts (0.60 ± 0.44 ng/ml). In addition, there was no correlation between the CA-125 and cf-DNA levels (r = 0.127, P = 0.07), with sensitivity of 96% and specificity of 84%, with a cutoff limit of 1.4 ng/ml in diagnosing malignancy.Conclusion Detection of cf-DNA holds promise as a diagnostic test for women with ovarian cancer. We recommend its incorporation into the workup investigations for women attending with adnexal mass.